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GHSR encodes a member of the G-protein coupled receptor family. Additionally we are shipping GHSR Kits (15) and GHSR Proteins (4) and many more products for this protein.
Showing 10 out of 79 products:
Human Polyclonal GHSR Primary Antibody for EIA, IHC (p) - ABIN952512
Landgren, Jerlhag, Hallman, Oreland, Lissner, Strandhagen, Thelle, Zetterberg, Blennow, Engel: Genetic variation of the ghrelin signaling system in females with severe alcohol dependence. in Alcoholism, clinical and experimental research 2010
Show all 2 references for ABIN952512
The effects of dietary energy on the metabolism of ghrelin (show GHRL Antibodies), leptin (show LEP Antibodies) and growth hormone secretagogue receptor in blood and tissues of steers are reported.
The coding regions of GHSR and SLC2A2 (show SLC2A2 Antibodies) were sequenced in 12 animals with extreme phenotypes for feed intake and gain; Sixteen SNPs were identified in SLC2A2 (show SLC2A2 Antibodies), and three were detected in GHSR.
provided conclusive evidence that the 19-TG allele of the 5'UTR (show UTS2R Antibodies) microsatellite of the bovine GHSR1a gene affects growth and carcass traits in Japanese Black cattle
We evaluated the haplotype variety and characterized the microsatellite ((TG)(n) , 5'-UTR (show UTS2R Antibodies)) and nucleotide polymorphisms of the bovine GHSR1a gene.
The data indicates that GHSR hypermethylation is a pan (show SUPT6H Antibodies)-cancer marker regardless of the tissue from which the tumor originates.
the single nucleotide polymorphism of GHSR might be weaker association with cancer risk, especially with breast cancer risk
Data (including data from knockout mice) suggest ghrelin (show GHRL Antibodies) produced in pancreatic islets regulates insulin (show INS Antibodies) secretion and thereby regulates blood glucose; ghrelin (show GHRL Antibodies) signaling via growth hormone secretagogue-receptor appears to be involved. [REVIEW]
This study suggests that the rs696217 and rs2075356 ghrelin (show GHRL Antibodies) gene (GHRL (show GHRL Antibodies)) polymorphisms may protect carriers against breast cancer, and the rs4684677 GHRL (show GHRL Antibodies) and rs572169 GHSR polymorphisms may increase the risk among carriers.[Meta-analysis]
The Ghr (show GHR Antibodies) and GHSR-1a were co-expressed by the pigmented epithelium (PE) of the CB, by the retinal pigmented epithelium (RPE (show RPE Antibodies)) and by the anterior limiting layer (ALL) of the iris.
Data indicate that activation of growth hormone secretagogue receptor (GHSR) may trigger a diversity of signaling mechanisms and subsequent distinct physiological responses.
Immunohistochemical staining revealed expression of ghrelin (show GHRL Antibodies) and GHSR1alpha both in glandular endometrioid epithelium and in some stromal cells, particularly in some fibroblasts, blood vessels and infiltrating leukocytes.
Ghrelin (show GHRL Antibodies) induces cell proliferation, migration and invasion via GHS-R/NF-kappaB (show NFKB1 Antibodies) signaling pathway in gastric cancer cells.
We found that ghrelin (show GHRL Antibodies) and GHSR1a are expressed in ovarian epithelial carcinoma in vivo and in vitro. Ghrelin (show GHRL Antibodies) inhibits the proliferation and growth of HO-8910 cells by G1 phase arrest.
In the posterior segment, the ghrelin (show GHRL Antibodies)-GHSR-1a system interferes with the development of oxygen-induced retinopathy, being protective in the vaso-obliterative phase and deleterious in the vaso-proliferative stage of the disease. (Review)
Study demonstrated that NMDAR (show GRIN1 Antibodies) functions are regulated by ghrelin (show GHRL Antibodies) in a GHSR1a-dependent manner: NMDAR (show GRIN1 Antibodies)-mediated synaptic currents are increased as a result of GluN1 (show GRIN1 Antibodies) subunit phosphorylation in the hippocampal pyramidal neurons and synapses
Ghsr mediates the beneficial effects of Caloric restriction on enhancing adult hippocampal neurogenesis and memory.
Data show that chronic caloric restriction (CR) alters hypothalamic agouti-related protein (Agrp (show AGRP Antibodies)) and neuropeptide Y (Npy (show NPY Antibodies)) gene expression similarly in Ghrelin (show GHRL Antibodies)+/+, Ghrelin (show GHRL Antibodies)-/-, ghrelin receptor Ghsr+/+, and Ghsr-/- mice.
The expression of ghrelin (show GHRL Antibodies) and GH secretagogue receptor 1a [GHSR1a] in cerebral arteries and the effects of ghrelin (show GHRL Antibodies) analogs on cerebrovascular function are reproted.[GHSR1a]
Thus, GHSR1a differentially inhibits CaV2 (show CAV2 Antibodies) channels by Gi/o or Gq protein pathways depending on its mode of activation.
The results of this study indicated that ghrelin receptor signaling is not required for flavor preferences conditioned by the oral or post-oral actions of sugar and fat.
Findings identify a previously unrecognized mechanism essential for DRD1 (show DRD1 Antibodies) initiation of hippocampal synaptic plasticity that is dependent on GHSR1a, and independent of cAMP signaling.
The expressions of both ghrelin (show GHRL Antibodies) and its receptor were observed in NPCs using RT-PCR, Interestingly, the exposure of fetal NPCs to ghrelin (show GHRL Antibodies) suppressed their proliferation, and caused them to differentiate into neurons
This study demonistrated that Ghsr expression in hippocampus and brainstem.
Ghrl (show GHRL Antibodies)-/- mice had lower cortical bone mass, whereas Ghsr-/- mice had lower trabecular bone mass. This demonstrates bone compartment-specific effects of acetylated ghrelin (show GHRL Antibodies) and a role for unacetylated Ghrelin (show GHRL Antibodies) in bone metabolism.
GHSR-1a is present in prepubertal pig ovary; no influence of GH on GHSR-1a expression is found.
This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein\; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin\; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
, growth hormone secretagogue receptor type 1
, growth hormone secretagogue receptor
, ghrelin/growth hormone secretagogue receptor
, growth hormone secretagogue receptor type 1A
, growth hormone secretagogue receptor, type 1A
, growth hormone secretagogue receptor type 1-like
, GH-releasing peptide receptor
, G-protein coupled receptor
, growth hormone secretagogue receptor type 1b