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Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) ELISA Kits

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. Additionally we are shipping GNAI1 Antibodies (38) and GNAI1 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse GNAI1 GNAI1 14677 B2RSH2
Anti-Human GNAI1 GNAI1 2770 P63096
Anti-Rat GNAI1 GNAI1 25686 P10824
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More ELISA Kits for GNAI1 Interaction Partners

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) interaction partners

  1. stimulation of GPR17 (show GPR17 ELISA Kits) by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreases myelin basic protein (show MBP ELISA Kits) expression levels mainly by triggering the Galphai/o signaling pathway.

  2. Gnai1 missense mutation is responsible of hyperpigmentation in mouse model.

  3. acidosis in inflamed tissues may be a decisive factor to regulate switching of PKA and PKCepsilon dependence via proton-sensing G-protein-coupled receptors.

  4. Data show that guanine nucleotide-binding protein G(i) subunit alpha-1 and alpha-3 (Galphai1/3) can interact with CD14 antigen/Grb2-associated binding protein Gab1, which modulates macrophage polarization in vitro and in vivo.

  5. By using mice deficient in individual Galphai/o G-protein subunits, authors demonstrate that Galphai1 and Galphai3 are the critical in vivo targets of ADP-ribosylation underlying vasoactive amine sensitization elicited by pertussis toxin exposure.

  6. leucine can directly facilitate insulin (show INS ELISA Kits) signaling through a Galphai protein-dependent intracellular signaling pathway

  7. Inactive Galpha(i1)-GDP enhances the affinity of RGS14 for H-Ras-GTP in live cells, resulting in a ternary signaling complex that is further regulated by G protein-coupled receptors.

  8. Mice with mutations of Gnai1 or Gnai2 (show GNAI2 ELISA Kits) have neither fusions of ribs nor lumbar vertebrae, but loss of both Gnai3 (show GNAI3 ELISA Kits) and one of the other two genes increases the number and severity of rib fusions without affecting the lumbar fusions.

  9. Results suggest a model in which the Gbetagamma dimer that is released as a result of the dissociation from Galpha(o (show GNAO1 ELISA Kits)) upon activation of mGluR6 (show GRM6 ELISA Kits) closes the TRPM1 (show TRPM1 ELISA Kits) channel, perhaps via a direct interaction.

  10. RGS14 (show RGS16 ELISA Kits) can form complexes with GPCRs in cells that are dependent on Galpha (show SUCLG1 ELISA Kits)(i/o) and these RGS14 (show RGS16 ELISA Kits).Galpha (show SUCLG1 ELISA Kits)(i1).GPCR (show GPBAR1 ELISA Kits) complexes may be substrates for other signaling partners such as Ric-8A (show RIC8A ELISA Kits)

Human Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) interaction partners

  1. Data indicate that hydroxyurea (HU) induces SAR1 (show IQGAP1 ELISA Kits) protein expression, which in turn activates gamma-globin (show HBG1 ELISA Kits) expression, predominantly through the Gialpha/JNK (show MAPK8 ELISA Kits)/Jun (show JUN ELISA Kits) pathway.

  2. Gi alpha subunit (show POLG ELISA Kits) was found to be a key modulator of GABAB-receptors signaling in analgesia.

  3. AC5, by binding active Galphai1, interferes with G-protein deactivation and reassembly and thereby might sensitize its own regulation.

  4. Data indicate that focal adhesion kinase (FAK) activation and cell migration require Src, Gi/Go, COX-2 and LOXs activities.

  5. resistin (show RETN ELISA Kits) contributes to the pro-inflammatory state of SMC (show DYM ELISA Kits) by the up-regulation of CX3CL1 (show CX3CL1 ELISA Kits) and CX3CR1 (show CX3CR1 ELISA Kits) expression via a mechanism involving NF-kB, AP-1 (show FOSB ELISA Kits), and STAT1 (show STAT1 ELISA Kits)/3 transcription factors, (2) resistin (show RETN ELISA Kits) employs TLR4 (show TLR4 ELISA Kits) and Gi-protein signaling.

  6. leucine can directly facilitate insulin (show INS ELISA Kits) signaling through a Galphai protein-dependent intracellular signaling pathway

  7. Data suggest that chemokine (show CCL1 ELISA Kits) binding to CCX-CKR (show CCRL1 ELISA Kits) (a) recruits Gi proteins and beta-arrestin (beta-arr (show SAG ELISA Kits)) with high affinity.

  8. This study support a role for RGS (show PITX2 ELISA Kits) proteins as negative regulators of opioid supraspinal antinociception and also reveal a potential novel function of RGS (show PITX2 ELISA Kits) proteins as positive regulators of opioid spinal antinociceptive pathways.

  9. Galpha(o (show GNAO1 ELISA Kits)) protein contributes to maximally efficient mu-opioid receptor (show OPRM1 ELISA Kits) signaling and antinociception in Galpha(o (show GNAO1 ELISA Kits)) null transgenic mice.

  10. CXCL12 (show CXCL12 ELISA Kits) signaling via CXCR7 (show CXCR7 ELISA Kits) is Gialpha independent.

GNAI1 Antigen Profile

Antigen Summary

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GNAI1

  • guanine nucleotide binding protein (G protein), alpha inhibiting 1 (Gnai1) antibody
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (gnai1-b) antibody
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (GNAI1) antibody
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (Gnai1) antibody
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (gnai1) antibody
  • AU046200 antibody
  • BPGTPB antibody
  • Gi antibody
  • Gialpha1 antibody
  • Gnai-1 antibody
  • gnai1 antibody
  • zgc:63957 antibody

Protein level used designations for GNAI1

adenylate cyclase-inhibiting G alpha protein , guanine nucleotide binding protein, alpha inhibiting 1 , guanine nucleotide-binding protein G(i) subunit alpha-1 , Gi1 protein alpha-subunit , alpha-subunit of G-protein, type G-alpha-i-1 , guanine nucleotide-binding protein G(i), alpha-1 subunit , Gi1 protein alpha subunit , Gi-alpha-1 protein , guanine nucleotide binding protein (G protein), alpha inhibiting 1 , Galpha i1a

GENE ID SPECIES
14677 Mus musculus
100135528 Cavia porcellus
399463 Xenopus laevis
396368 Gallus gallus
2770 Homo sapiens
397505 Sus scrofa
281790 Bos taurus
25686 Rattus norvegicus
393946 Danio rerio
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