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anti-Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1) Antibodies

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Additionally we are shipping GNAT1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GNAT1 2779 P11488
GNAT1 363143  
GNAT1 14685 P20612
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Top anti-GNAT1 Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Flow cytometric analysis of Jurkat cells using GNAT1 Antibody (C-term) Cat.-No AP51875PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded moouse heart tissue reacted with GNAT1 Antibody (C-term) followed which was  peroxidase conjugated to the secondary antibody and followed by AB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COLO cells, using GNAT1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of GNAT1 Antibody (C-term) (ABIN653740) in Jurkat cell line lysates (35 µg/lane). GNAT1 (arrow) was detected using the purified polyclonal antibody. GNAT1 Antibody (C-term) (ABIN653740) IHC analysis in formalin fixed and paraffin embedded moouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: U87-MG 10% SDS PAGE antibody diluted at 1:3000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of GNAT1 staining in human heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of GNAT1 expression in U87MG (A), mouse brain (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

GNAT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,
Rat (Rattus)


Mouse (Murine)


Top referenced anti-GNAT1 Antibodies

  1. Human Polyclonal GNAT1 Primary Antibody for FACS, IHC (p) - ABIN955309 : Szabo, Kreienkamp, Rosenberg, Gal: p.Gln200Glu, a putative constitutively active mutant of rod alpha-transducin (GNAT1) in autosomal dominant congenital stationary night blindness. in Human mutation 2007 (PubMed)
    Show all 4 references for ABIN955309

  2. Human Polyclonal GNAT1 Primary Antibody for ELISA, WB - ABIN1534969 : Lerea, Bunt-Milam, Hurley: Alpha transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina. in Neuron 1990 (PubMed)

More Antibodies against GNAT1 Interaction Partners

Cow (Bovine) Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1) interaction partners

  1. These results indicated that efficient Gt activation by rhodopsin (show RHO Antibodies), resulting from an optimized active state of rhodopsin (show RHO Antibodies), is one of the causes of the high amplification efficiency of rods.

Human Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1) interaction partners

  1. These data suggest that some truncating GNAT1 variants can indeed cause a recessive, mild, late-onset retinal degeneration in human beings rather than just stationary night-blindness as reported previously.

  2. Three candidate tumor-suppressor genes, SEMA3B (show SEMA3B Antibodies), AXUD1 (show CSRNP1 Antibodies) and GNAT1 may be involved in oral squamous cell carcinoma.

  3. These data suggest that a homozygous missense mutation in GNAT1 is associated with autosomal recessive stationary night blindness.

  4. Expression of GNAT1 gene is down-regulated or absent in nasopharyngeal carcinoma tissues.

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1) interaction partners

  1. Data suggest light reduces oxygen consumption rate (OCR) of retina; light does not affect OCR in retinas of Gnat1-/- knockout mice (phototransduction disabled). Light reduces cGMP in retina; light does not alter cGMP in Gnat1-/- plus Gnat2 (show GNAT2 Antibodies)-/- retina.

  2. Biochemical changes, including reduced transducin protein levels and enhanced transducin GTPase (show RACGAP1 Antibodies) activity, explain the shift in light intensity threshold for Galphat1 translocation in Rs1 (show RS1 Antibodies)-knockout mice.

  3. The results from shaker1 and whirler (show DFNB31 Antibodies) mice suggest that defective transducin translocation may be functionally related to light-induced degeneration.

  4. ectopically expressed cTalpha (show PCYT1A Antibodies) 1) forms a heterotrimeric complex with rod Gbeta (show SUCLG2 Antibodies)(1)gamma(1), and substitutes equally for rTalpha in generating photoresponses initiated by either rhodopsin (show RHO Antibodies) or S-cone opsin (show RHO Antibodies)

  5. Oligomerization incompetent retinal degeneration slow (show PRPH2 Antibodies) is associated with mislocalization of cone opsins and cone transducin.

  6. Data show that visual responses in TKO (show MRPS12 Antibodies) mice extend beyond the retina to encompass the lateral margins of the lateral geniculate nucleus and components of the visual cortex.

  7. Thus our results showed that IRD1 and IRD2 mice harbor a nonsense mutation in the Gnat1 gene, resulting in the absence or suppressed expression of the Tralpha protein, which is the likely cause of rod dysfunction in both mutants.

  8. alpha-transducin can function in taste receptor cells and transduce some taste cell responses

  9. data suggest that phosducin (show PDC Antibodies) action is based on the reduction of transducin affinity to the membranes of rod outer segments, achieved by keeping the transducin beta gamma subunits apart from the alpha subunit (show POLG Antibodies).

  10. Alpha-transducin played no role in regulating adaptive response to light. Degeneration does not require transducin-mediated signaling.

GNAT1 Antigen Profile

Protein Summary

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.

Gene names and symbols associated with GNAT1

  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (GNAT1) antibody
  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (gnat1) antibody
  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (Gnat1) antibody
  • guanine nucleotide binding protein, alpha transducing 1 (Gnat1) antibody
  • CSNBAD3 antibody
  • GBT1 antibody
  • Gnat-1 antibody
  • GNAT1 antibody
  • GNATR antibody
  • Ird1 antibody
  • Ird2 antibody
  • irdc antibody
  • irdr antibody
  • Tralpha antibody
  • transducin antibody
  • wu:fk56e06 antibody

Protein level used designations for GNAT1

guanine nucleotide-binding protein G(t) subunit alpha-1 , rod-type transducin alpha subunit , guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 , guanine nucleotide binding protein, alpha transducing activity polypeptide 1 , guanine nucleotide-binding protein G(t) subunit alpha-1-like , transducin alpha-1 chain , guanine nucleotide-binding protein G(T), alpha-1 subunit , transducin, rod-specific , guanine nucleotide binding protein (G protein), alpha transducing 1 , guanine nucleotide binding protein, alpha transducing 1 , Galpha t1 , fk56e06 , rod transducin alpha subunit , transducin alpha (rod) , rod photoreceptor transducin alpha 1 subunit , transducin alpha subunit GNAT1

GENE ID SPECIES
395426 Gallus gallus
703881 Macaca mulatta
744813 Pan troglodytes
100124843 Xenopus (Silurana) tropicalis
100457419 Pongo abelii
281794 Bos taurus
2779 Homo sapiens
363143 Rattus norvegicus
140428 Danio rerio
403613 Canis lupus familiaris
444825 Xenopus laevis
14685 Mus musculus
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