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anti-Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 2 (GNAT2) Antibodies

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. Additionally we are shipping GNAT2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GNAT2 2780 P19087
GNAT2 365901  
GNAT2 14686 P50149
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Top anti-GNAT2 Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human Kidney tissue reacted with GNAT2 / GNATC Antibody (Center) Cat.-No AP51876PU-N peroxidase conjugated to the secondary antibody and followed by  DAB staining. Western blot analysis of GNAT2 / GNATC Antibody (Center) in mouse spleen tissue lysates (35ug/lane). This demonstrates the GNAT2 antibody detected the GNAT2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COLO cells, using GNAT2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB GNAT2 antibody (Center) (ABIN655029) immunohistochemistry analysis in formalin fixed and paraffin embedded human Kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry (IHC) analyzes of Gαt2 antibody in paraffin-embedded human testis tissue. Western blot (WB) analysis of Gα t2 antibody in extracts from COLO cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details

GNAT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GNAT2 Antibodies

  1. Human Polyclonal GNAT2 Primary Antibody for EIA, IHC (p) - ABIN952564 : Oldham, Van Eps, Preininger, Hubbell, Hamm: Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins. in Nature structural & molecular biology 2006 (PubMed)
    Show all 2 references for ABIN952564

  2. Human Polyclonal GNAT2 Primary Antibody for ELISA, WB - ABIN1534970 : Morris, Fong: Characterization of the gene encoding human cone transducin alpha-subunit (GNAT2). in Genomics 1993 (PubMed)
    Show all 2 references for ABIN1534970

More Antibodies against GNAT2 Interaction Partners

Zebrafish Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 2 (GNAT2) interaction partners

  1. this study describes several functional differences between transducin (show GNAT1 Antibodies) gene duplicates resulting from the teleost-specific tetraploidisation.

  2. identifed cis (show CISH Antibodies)-regulatory elements in upstream promoter region of the TalphaC gene; found PRE-1 is a novel cis (show CISH Antibodies)-regulatory module that is sufficient to enhance initiation of photoreceptor-specific gene expression in differentiating rod and cone photoreceptors

  3. Ca2 (show CA2 Antibodies)+ also regulates the extent of phosphorylation of unbleached cone pigments. Immunocytochemical analyses revealed that neither light nor cytoplasmic Ca2 (show CA2 Antibodies)+ influences the localization of transducin (show GNAT1 Antibodies) in zebrafish cones.

Human Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 2 (GNAT2) interaction partners

  1. The majority (n = 12) of patients were either homozygotes or compound heterozygotes for known achromatopsia alleles, two in CNGB3 (show CNGB3 Antibodies) (p.T383fsX and p.T296YfsX9) and three in CNGA3 (show CNGA3 Antibodies) (p.R283Q, p.R427C and p.L527R).

  2. Single nucleotide polymorphisms in GNAT2 gene is associated with obesity.

  3. Expression of GNAT2 transgene, when found in rod photoreceptor cells rather than in cones, demonstrates different mechanisms of amplification in the body's G-protein alpha (show GNAO1 Antibodies) cascades and the activation of phosphodiesterase 6.

  4. Clinical and genetic investigation of a large Tunisian family with complete achromatopsia: identification of a new nonsense mutation in GNAT2 gene.

  5. mutations in GNAT2 are implicated in achromatopsia

  6. We detected a deletion of a highly conserved lysine at codon 270 in a critical functional area of the alpha-cone transducin (show GNAT1 Antibodies) molecule, and therefore is not the disease causing mutation.

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 2 (GNAT2) interaction partners

  1. Data suggest light reduces oxygen consumption rate (OCR) of retina; light does not affect OCR in retinas of Gnat1 (show GNAT1 Antibodies)-/- knockout mice (phototransduction disabled). Light reduces cGMP in retina; light does not alter cGMP in Gnat1 (show GNAT1 Antibodies)-/- plus Gnat2-/- retina.

  2. The Gnat2(c.518A>G) mouse contains a missense mutation that results in no cone function due to a misfolding of transducin (show GNAT1 Antibodies). Cone photoreceptors also show signs of opsin (show RHO Antibodies) mislocalization, retinal remodeling and degeneration.

  3. The Gnat2(cpfl3) mutation leads to cone dysfunction and the progressive loss of cone alpha-transducin (show GNAT1 Antibodies) immunolabeling.

  4. rod and cone transducin alpha-subunits are functionally interchangeable and their signaling properties do not contribute to the intrinsic light sensitivity differences between rods and cones

GNAT2 Antigen Profile

Protein Summary

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones.

Gene names and symbols associated with GNAT2

  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (gnat2) antibody
  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (GNAT2) antibody
  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (Gnat2) antibody
  • guanine nucleotide binding protein, alpha transducing 2 (Gnat2) antibody
  • ACHM4 antibody
  • AW490837 antibody
  • Gnat-2 antibody
  • GNATC antibody
  • Gt-2 antibody
  • Tcalpha antibody

Protein level used designations for GNAT2

GNAT3 , Galpha t2 , T alpha C , Tc alpha , cone transducin alpha subunit , guanine nucleotide-binding protein G(t) subunit alpha-2 , no optokinetic response f , nof , transducin alpha (cone) , cone-type transducin alpha subunit , transducin alpha-2 chain , transducin, cone-specific, alpha polypeptide , guanine nucleotide binding protein (G protein), alpha transducing 2 , guanine nucleotide binding protein, alpha transducing 2

GENE ID SPECIES
140429 Danio rerio
2780 Homo sapiens
281795 Bos taurus
395425 Gallus gallus
490119 Canis lupus familiaris
365901 Rattus norvegicus
14686 Mus musculus
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