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Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 2 Proteins (GNAT2)

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. Additionally we are shipping GNAT2 Antibodies (45) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GNAT2 2780 P19087
Rat GNAT2 GNAT2 365901  
GNAT2 14686 P50149
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Top GNAT2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,960.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

GNAT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 2 (GNAT2) Interaction Partners

Zebrafish Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 2 (GNAT2) interaction partners

  1. this study describes several functional differences between transducin (show GNAT1 Proteins) gene duplicates resulting from the teleost-specific tetraploidisation.

  2. identifed cis (show CISH Proteins)-regulatory elements in upstream promoter region of the TalphaC gene; found PRE-1 is a novel cis (show CISH Proteins)-regulatory module that is sufficient to enhance initiation of photoreceptor-specific gene expression in differentiating rod and cone photoreceptors

  3. Ca2 (show CA2 Proteins)+ also regulates the extent of phosphorylation of unbleached cone pigments. Immunocytochemical analyses revealed that neither light nor cytoplasmic Ca2 (show CA2 Proteins)+ influences the localization of transducin (show GNAT1 Proteins) in zebrafish cones.

Human Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 2 (GNAT2) interaction partners

  1. The majority (n = 12) of patients were either homozygotes or compound heterozygotes for known achromatopsia alleles, two in CNGB3 (show CNGB3 Proteins) (p.T383fsX and p.T296YfsX9) and three in CNGA3 (show CNGA3 Proteins) (p.R283Q, p.R427C and p.L527R).

  2. Single nucleotide polymorphisms in GNAT2 gene is associated with obesity.

  3. Expression of GNAT2 transgene, when found in rod photoreceptor cells rather than in cones, demonstrates different mechanisms of amplification in the body's G-protein alpha (show GNAO1 Proteins) cascades and the activation of phosphodiesterase 6.

  4. Clinical and genetic investigation of a large Tunisian family with complete achromatopsia: identification of a new nonsense mutation in GNAT2 gene.

  5. mutations in GNAT2 are implicated in achromatopsia

  6. We detected a deletion of a highly conserved lysine at codon 270 in a critical functional area of the alpha-cone transducin (show GNAT1 Proteins) molecule, and therefore is not the disease causing mutation.

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 2 (GNAT2) interaction partners

  1. Data suggest light reduces oxygen consumption rate (OCR) of retina; light does not affect OCR in retinas of Gnat1 (show GNAT1 Proteins)-/- knockout mice (phototransduction disabled). Light reduces cGMP in retina; light does not alter cGMP in Gnat1 (show GNAT1 Proteins)-/- plus Gnat2-/- retina.

  2. The Gnat2(c.518A>G) mouse contains a missense mutation that results in no cone function due to a misfolding of transducin. Cone photoreceptors also show signs of opsin mislocalization, retinal remodeling and degeneration.

  3. The Gnat2(cpfl3) mutation leads to cone dysfunction and the progressive loss of cone alpha-transducin (show GNAT1 Proteins) immunolabeling.

  4. rod and cone transducin alpha-subunits are functionally interchangeable and their signaling properties do not contribute to the intrinsic light sensitivity differences between rods and cones

GNAT2 Protein Profile

Protein Summary

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones.

Gene names and symbols associated with GNAT2

  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (gnat2)
  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (GNAT2)
  • guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (Gnat2)
  • guanine nucleotide binding protein, alpha transducing 2 (Gnat2)
  • ACHM4 protein
  • AW490837 protein
  • Gnat-2 protein
  • GNATC protein
  • Gt-2 protein
  • Tcalpha protein

Protein level used designations for GNAT2

GNAT3 , Galpha t2 , T alpha C , Tc alpha , cone transducin alpha subunit , guanine nucleotide-binding protein G(t) subunit alpha-2 , no optokinetic response f , nof , transducin alpha (cone) , cone-type transducin alpha subunit , transducin alpha-2 chain , transducin, cone-specific, alpha polypeptide , guanine nucleotide binding protein (G protein), alpha transducing 2 , guanine nucleotide binding protein, alpha transducing 2

GENE ID SPECIES
140429 Danio rerio
2780 Homo sapiens
281795 Bos taurus
395425 Gallus gallus
490119 Canis lupus familiaris
365901 Rattus norvegicus
14686 Mus musculus
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