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Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. Additionally we are shipping GNB1 Kits (29) and GNB1 Proteins (4) and many more products for this protein.
Showing 10 out of 58 products:
Human Polyclonal GNB1 Primary Antibody for FACS, WB - ABIN651226
Ahmed, Daulat, Meunier, Angers: G protein betagamma subunits regulate cell adhesion through Rap1a and its effector Radil. in The Journal of biological chemistry 2010
Show all 4 references for ABIN651226
Dog (Canine) Polyclonal GNB1 Primary Antibody for WB - ABIN2785813
Ueda, Nagae, Kozawa, Morishita, Kimura, Nagase, Ohara, Yoshida, Asano: Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42. in The Journal of biological chemistry 2008
Human Polyclonal GNB1 Primary Antibody for WB - ABIN4315227
Stockton, Gomes, Liu, Moraje, Hipólito, Jones, Maayan, Morón, Li, Devi: Morphine Regulated Synaptic Networks Revealed by Integrated Proteomics and Network Analysis. in Molecular & cellular proteomics : MCP 2015
During corticogenesis, a cilium-transduced, noncanonical IGF-1R (show IGF1R Antibodies)-Gbetagamma-phospho(T94)Tctex-1 (show DYNLT1 Antibodies) signaling pathway promotes the proliferation of neural progenitors through modulation of ciliary resorption and G1 length.
ectopically expressed cTalpha (show PCYT1A Antibodies) 1) forms a heterotrimeric complex with rod Gbeta (show SUCLG2 Antibodies)(1)gamma(1), and substitutes equally for rTalpha in generating photoresponses initiated by either rhodopsin (show RHO Antibodies) or S-cone opsin (show RHO Antibodies)
Results suggest a model in which the Gbetagamma dimer that is released as a result of the dissociation from Galpha(o (show GNAO1 Antibodies)) upon activation of mGluR6 (show GRM6 Antibodies) closes the TRPM1 (show TRPM1 Antibodies) channel, perhaps via a direct interaction.
WDR26 (show WDR26 Antibodies) is a novel Gbetagamma-binding protein that is required for the efficacy of Gbetagamma signaling and leukocyte migration
Our data suggest that the G-protein beta(1)gamma(2) dimer may play an important regulatory role in skeletal muscle excitation-contraction coupling.
G protein subunits beta1 and beta2 have different roles in neutrophil function, as revealed by gene expression silencing in primary mouse neutrophils
G betagamma binds HDAC5 (show HDAC5 Antibodies) and inhibits its transcriptional co-repression activity
G protein betagamma subunits stimulate type V and VI adenylyl cyclases
signaling pathway by which G(i)-coupled receptor specifically induces Rac (show AKT1 Antibodies) and Cdc42 (show CDC42 Antibodies) activation through direct interaction of Gbetagamma with FLJ00018.
Gbeta1 is the predominant Gbeta (show SUCLG2 Antibodies) subunit expressed in olfactory sensory neurons.
PhLP1 binding stabilizes the Gbeta (show SUCLG2 Antibodies) fold, disrupting interactions with CCT (show FLVCR2 Antibodies) and releasing a PhLP1-Gbeta (show SUCLG2 Antibodies) dimer for assembly with Ggamma.
GNB1 and GNB2 alterations confer transformed and resistance phenotypes across a range of human tumors and may be targetable with inhibitors of G protein signaling.
Data indicate that endogenous mTOR (show FRAP1 Antibodies) interacts with Gbetagamma.
GNB1 plays an important role in the mTOR (show FRAP1 Antibodies)-related anti-apoptosis pathway and can potentially be targeted in the treatment of human breast cancer.
Findings suggest a wide-ranging mechanism by which direct interaction of Gbetagamma with specific chromatin bound transcription factors regulates functional gene networks in response to GPCR (show NMUR1 Antibodies) activation in cells including the angiotensin II type 1 receptor (show AGTR1 Antibodies).
This study provided evidence that GNB1 gene polymorphisms are related to rapid virological response in HCV-1 and HCV-2 (show BMPER Antibodies) infected patients. GNB1 may play an important role in activating the antiviral response prior to treatment.
Gbetagamma inhibits Epac (show RAPGEF3 Antibodies)-induced Ca 2 (show CA2 Antibodies)+ elevation in melanoma cells. Cross talk of Ca 2 (show CA2 Antibodies)+ signaling between Gbetagamma & Epac (show RAPGEF3 Antibodies) plays a major role in melanoma cell migration.
Data implicate the domain I-II linker region as an important contributor to voltage dependent Gbeta1/Ggamma2 modulation of Cav2.2 (show CACNA1B Antibodies) calcium channels.
Gbeta1gamma2-mediated epithelial sodium channel (ENaC (show SCNN1A Antibodies)) inhibition involves activation of phospholipase C-beta (show PLCb4 Antibodies) and its enzymatic products that induce protein kinase C (show PKC Antibodies) and ERK1/2 (show MAPK1/3 Antibodies) signaling pathways.
determined the crystallographic structure of GRK2 in complex with G protein beta1gamma2 subunits
conclude that GNB1 constitutes over 99% of the GNbeta expressed in bovine rod outer segments and displays structural heterogeneity that is due to post-translational modification, some of which is due to phosphorylation of GNB1.
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals.
guanine nucleotide binding protein, beta 1
, guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
, transducin beta chain 1
, G protein, beta-1 subunit
, beta subunit, signal-transducing proteins GS/GI
, guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1
, Guanine nucleotide-binding protein beta 1
, guanine nucleotide binding protein (G protein), beta 1
, guanine nucleotide-binding protein, beta-1 subunit
, rod transducin
, beta 1 subunit of heterotrimeric GTP-binding protein