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may play a role in D5 dopamine receptor signal transduction and renal sodium transport. Additionally we are shipping GNA12 Antibodies (53) and and many more products for this protein.
the current studies provide evidence showing that c-Jun (show JUN ELISA Kits) directly binds to a consensus binding sequence within the GNA12-5' regulatory region, thereby regulating GNA12 transcription.
we conclude that Galpha12 protects HUVECs[ human umbilical vein endothelial cells ] from serum withdrawal-induced apoptosis by retaining miR (show MLXIP ELISA Kits)-155 expression.
RGS22 acts as a tumor suppressor, repressing human pancreatic adenocarcinoma cell migration by coupling to GNA12/13.
preeclampsia is associated with decreased methylation of the GNA12 promoter
Data show that N-linked glycosylation of protease-activated receptor-1 (PAR1 (show F2R ELISA Kits)) at extracellular loop 2 (ECL2) controls G12 (show TCF3 ELISA Kits)/13 versus Gq G-proteins coupling specificity in response to thrombin (show F2 ELISA Kits) stimulation.
Significance of Galpha12 upregulation in liver tumor progression, implicating Galpha12 as an attractive therapeutic target.
Results show that RMP (show ABCA4 ELISA Kits) serves as a potent factor contributing to portal vein tumor thrombus by promoting IL-6 (show IL6 ELISA Kits) transcription.
A tyrosine residue at the C-terminus of the Galpha subunit plays an important role in controlling activation of G-protein coupled receptors.
Galpha12gep oncogene (show RAB1A ELISA Kits) inhibits FOXO1 (show FOXO1 ELISA Kits), which may result from the inhibition of FOXO1 (show FOXO1 ELISA Kits) de novo synthesis by miR (show MLXIP ELISA Kits)-135b in conjunction with MDM2 (show MDM2 ELISA Kits)-mediated destabilization of FOXO1 (show FOXO1 ELISA Kits).
CREB (show CREB1 ELISA Kits) is a critical signaling node in Lysophosphatidic acid-Lysophosphatidic acid receptor and Galpha12/gep proto-oncogene (show RAB1A ELISA Kits) stimulated oncogenic signaling in ovarian cancer cells.
Gpr56 (show GPR56 ELISA Kits) regulates oligodendrocyte development via interactions with Galpha12/13 and RhoA (show RHOA ELISA Kits)
Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton.
Galpha12 is required for the development of kidney cysts induced by Pkd1 (show PKD1 ELISA Kits) mutation in mouse autosomal dominant polycystic kidney disease.
Our data reveal a previously unknown role for Galpha12 in regulating efferocytosis and that renal tubular epithelial cells require KIM-1 (show HAVCR1 ELISA Kits) to mediate this process.
Selective inhibition of G12 (show TCF3 ELISA Kits)/13 signaling in macrophages can augment atheroprotective B-cell populations and ameliorate atherosclerosis.
results suggest that KIM-1 (show HAVCR1 ELISA Kits) is an endogenous protective mechanism against renal ischemia-reperfusion injury through inhibition of Galpha12.
Pkd1 (show PKD1 ELISA Kits) mutation or deletion leads to the activation of Galpha12, which promotes the maturation of ADAM10 (show ADAM10 ELISA Kits) that increases the shedding of E-cadherin (show CDH1 ELISA Kits) in kidney epithelial cells.
Galpha12 may play an important role in promoting membrane trafficking and exocytosis for basal and thrombin (show F2 ELISA Kits)-induced vWF (show VWF ELISA Kits) secretion, in a process involving SNAP, Galpha12/13 and Galphaq (show GNAQ ELISA Kits)/11
Data indicate that Pyk2 (show PTK2B ELISA Kits) is a common signaling effector downstream of both G12 (show TCF3 ELISA Kits)/13 and integrin alphaIIbbeta3 signaling, which contributes to thromboxane generation.
PRR5L (show PRR5L ELISA Kits) degradation promotes mTORC2 (show CRTC2 ELISA Kits)-mediated PKC-delta (show PKCd ELISA Kits) phosphorylation and cell migration downstream of Galpha12 in fibroblasts and pulmonary fibrosis.
Expression analysis reveals that production of 5-HT7 and Galpha12 proteins in the hippocampus undergoes strong regulation with a pronounced transient increase during early postnatal stages.
may play a role in D5 dopamine receptor signal transduction and renal sodium transport
G-protein subunit alpha-12
, g alpha-12
, guanine nucleotide-binding protein subunit alpha-12
, guanine nucleotide binding protein, alpha 12
, Galpha 12
, guanine nucleotide binding protein (G protein) alpha 12