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GMPR encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. Additionally we are shipping GMPR Proteins (11) and GMPR Kits (3) and many more products for this protein.
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Human Polyclonal GMPR Primary Antibody for IHC, IHC (p) - ABIN4315219
Wawrzyniak, Bianchi-Smiraglia, Bshara, Mannava, Ackroyd, Bagati, Omilian, Im, Fedtsova, Miecznikowski, Moparthy, Zucker, Zhu, Kozlova, Berman, Hoek, Gudkov, Shewach, Morrison, Nikiforov: A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion. in Cell reports 2013
GMPR as a suppressor of melanoma invasion is downregulated at the early invasive stages of melanoma progression and whose activity inhibits melanoma cell invasion by depleting intracellular GTP (show AK3 Antibodies) pools.
This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.
GMP reductase 1
, guanosine monophosphate reductase
, GMP reductase 1-like
, guanine monophosphate reductase
, guanosine 5'-monophosphate oxidoreductase 1
, guanosine monophosphate reductase 1