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Guanylate Binding Protein 1, Interferon-Inducible Proteins (GBP1)

Guanylate binding protein expression is induced by interferon. Additionally we are shipping Guanylate Binding Protein 1, Interferon-Inducible Antibodies (75) and Guanylate Binding Protein 1, Interferon-Inducible Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GBP1 2633 P32455
Rat GBP1 GBP1 304266  
GBP1 14468  
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Top Guanylate Binding Protein 1, Interferon-Inducible Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

GBP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced Guanylate Binding Protein 1, Interferon-Inducible Proteins

  1. Human GBP1 Protein expressed in Human Cells - ABIN2005263 : Naschberger, Lubeseder-Martellato, Meyer, Gessner, Kremmer, Gessner, Stürzl: Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis. in The American journal of pathology 2006 (PubMed)

More Proteins for Guanylate Binding Protein 1, Interferon-Inducible (GBP1) Interaction Partners

Human Guanylate Binding Protein 1, Interferon-Inducible (GBP1) interaction partners

  1. GBP1 promotes lymph node metastasis and has a positive correlation with EGFR (show EGFR Proteins) expression in esophageal squamous cell carcinoma.

  2. Molecular dynamics studies showed that only GTP (show AK3 Proteins) decreases the formation of the GBP1:PIM1 (show PIM1 Proteins) complex through an allosteric mechanism, outlining the rational for the identification of new compounds potentially able to revert resistance to paclitaxel.

  3. GBP1 overexpression is necessary for the radioresistant phenotype in clinically relevant radioresistant cells

  4. GBP-1 is a downstream processor of IFN-gamma (show IFNG Proteins).

  5. IFN-gamma-induced (show SAMHD1 Proteins) Guanylate Binding Protein-1 is a novel Actin Cytoskeleton Remodeling Factor. GBP-1 may induce actin remodeling via globular actin sequestering and/or filament capping. GBP-1 is a novel member within the family of actin remodeling proteins, specifically mediating IFN-gamma (show IFNG Proteins)-dependent defense strategies.

  6. Data indicate that among three deductive p53 (show TP53 Proteins) response element (p53RE) present in the hGBP1 promoter region, two p53REs were found to be transactivated by p53 (show TP53 Proteins).

  7. GBP1/2 are critical effectors of antichlamydial interferon (IFN)gamma (show IFNA Proteins)-mediated pathogen clearance via rerouting of bacterial inclusions in macrophages for lysosomal degradation.

  8. Cytokine-induced GBP-1 retards cell proliferation by forming a negative feedback loop that suppresses beta-catenin (show CTNNB1 Proteins) / TCF (show HNF4A Proteins) signaling.

  9. GBP1 inhibits proliferation, migration, invasion and tumor formation of colon tumor cells.

  10. Data indicate that GBP1 guanine cap (i.e., C-terminal guanine-binding amino acid motif, particularly Arg240/Arg244) is key structural element responsible for dimerization and is essential for self-activation of GTPase (show RACGAP1 Proteins) activity.

Pig (Porcine) Guanylate Binding Protein 1, Interferon-Inducible (GBP1) interaction partners

  1. GBP1 is associated with resistance against porcine reproductive and respiratory syndrome infection and efficient T cell activation in pigs.

  2. Allele A in GBP1, the unfavourable allele, is associated with higher PRRSV viremia levels and lower weight gain following infection

  3. cDNA sequences were cloned and the genomic structure of porcine GBP1 (poGBP1) and GBP2 (show GBP2 Proteins) (poGBP2), was analyzed.

Mouse (Murine) Guanylate Binding Protein 1, Interferon-Inducible (GBP1) interaction partners

  1. GBP1 GBP2 (show GBP2 Proteins) enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.

  2. These findings demonstrate that Gbp1 plays an important role in the IFN-gamma (show IFNG Proteins)-dependent, cell-autonomous control of toxoplasmosis and predict a broader role for this protein in host defense.

  3. findings show that at least 4 IFN-gamma (show IFNG Proteins)-inducible Gbps--Gbp1, Gbp6 (show GBP6 Proteins), Gbp7 (show GBP7 Proteins), and Gbp10--conferred cell-autonomous immunity to listerial or mycobacterial infection within macrophages and gene-deficient animals

  4. These findings identify a role for IFN-alphaA (show IFNA2 Proteins)-mediated GBP-1 expression in the prevention of intestinal epithelial apoptosis by commensal bacteria.

Guanylate Binding Protein 1, Interferon-Inducible (GBP1) Protein Profile

Protein Summary

Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.

Gene names and symbols associated with GBP1

  • guanylate binding protein 1, interferon-inducible (GBP1)
  • guanylate binding protein 1, interferon-inducible (Gbp1)
  • guanylate binding protein 1, interferon-inducible, 67kD (GBP1)
  • guanylate binding protein 2b (Gbp2b)
  • 5830475C06 protein
  • Gbp-1 protein
  • Gbp1 protein
  • Mag-1 protein
  • Mpa-1 protein
  • Mpa1 protein

Protein level used designations for GBP1

GBP-1 , GTP-binding protein 1 , guanine nucleotide-binding protein 1 , guanylate binding protein 1, interferon-inducible, 67kDa , huGBP-1 , interferon-induced guanylate-binding protein 1 , guanylate binding protein 1 , guanylate nucleotide binding protein 1 , interferon-gamma-inducible protein MAG-1 , mGBP-1 , mGBP1

GENE ID SPECIES
2633 Homo sapiens
304266 Rattus norvegicus
100172437 Pongo abelii
490172 Canis lupus familiaris
100151938 Sus scrofa
281185 Bos taurus
14468 Mus musculus
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