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Guanylate Binding Protein 2, Interferon-Inducible Proteins (GBP2)

Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. Additionally we are shipping Guanylate Binding Protein 2, Interferon-Inducible Antibodies (123) and Guanylate Binding Protein 2, Interferon-Inducible Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GBP2 54676 Q9BX10
GBP2 56055 Q3UJK4
GBP2 363195  
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Top Guanylate Binding Protein 2, Interferon-Inducible Proteins at antibodies-online.com

Showing 7 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cryphonectria parasitica His tag   1 mg Log in to see 56 to 66 Days
$2,979.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,685.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GBP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced Guanylate Binding Protein 2, Interferon-Inducible Proteins

  1. Human GBP2 Protein expressed in Human Cells - ABIN2006014 : Wistow, Bernstein, Wyatt, Fariss, Behal, Touchman, Bouffard, Smith, Peterson: Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. in Molecular vision 2002 (PubMed)
    Show all 2 references for ABIN2006014

More Proteins for Guanylate Binding Protein 2, Interferon-Inducible (GBP2) Interaction Partners

Xenopus laevis Guanylate Binding Protein 2, Interferon-Inducible (GBP2) interaction partners

  1. Gtpbp2 is required for BMP signaling and mesoderm patterning in Xenopus embryos.

Human Guanylate Binding Protein 2, Interferon-Inducible (GBP2) interaction partners

  1. Low GBP2 expression is associated with metastasis in breast cancer.

  2. GBP1 (show GBP1 Proteins)/2 are critical effectors of antichlamydial interferon (IFN)gamma (show IFNA Proteins)-mediated pathogen clearance via rerouting of bacterial inclusions in macrophages for lysosomal degradation.

  3. Downregulation of MIR (show MLXIP Proteins)-433 is associated with myeloproliferative neoplasms.

  4. The in vivo localization of GBP-2 at cellular membranes is regulated by isoprenylation and dimerization.

  5. hGBP-1, hGBP-2 showed dimerization-related GTPase (show RACGAP1 Proteins) activity for GMP (show NT5C2 Proteins) formation.

  6. Guanylate-binding protein 2 mRNA in peripheral blood leukocytes may have a role in acute cellular rejection after liver transplantation

  7. Sky1p utilizes the same docking groove to bind yeast SR-like protein (show PNN Proteins) Gbp2p and phosphorylates all three serines present in a contiguous RS dipeptide stretch

  8. GBP-2 is regulated by p53 (show TP53 Proteins) and may have a role in esophageal squamous cell carcinomas

Mouse (Murine) Guanylate Binding Protein 2, Interferon-Inducible (GBP2) interaction partners

  1. GBP1 (show GBP1 Proteins) GBP2 enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.

  2. this study identified guanylate-binding proteins GBP2 and GBP5 as key activators of AIM2 (show AIM2 Proteins) during infection with F. novicida.

  3. This study begins to define the properties of mGBP-2 responsible for inhibiting cell spreading.

  4. these results not only define GTPBP2 as a ribosome rescue factor but also unmask the disease potential of mutations in nuclear-encoded tRNA genes.

  5. Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.

  6. the inducible multimerization of mGBP2 is dependent on a functional GTPase (show RACGAP1 Proteins) domain.

  7. IRGM (show IRGM Proteins) proteins indirectly modulate the localization of GBP2 through a distinct mechanism from that through which they regulate IRG protein localization

  8. mGBP-2 inhibits TNF-alpha (show TNF Proteins) activation of endogenous Rac1 and constitutively activate Rac (show AKT1 Proteins) can restore NF-kappaB (show NFKB1 Proteins) transcription in the presence of mGBP-2. This is a novel mechanism by which IFNs can inhibit the cytokine induction of MMP-9 (show MMP9 Proteins) expression.

  9. Both IFN-gamma (show IFNG Proteins) and mGBP-2 also inhibit cell spreading initiated by platelet-derived growth factor treatment, which is also accompanied by inhibition of Rac (show AKT1 Proteins) activation by mGBP-2.

  10. inhibits replication of both vesicular stomatitis virus (VSV) and encephalomyocarditis virus (EMCV); a wild type GTP binding (show RND2 Proteins) motif was not required for VSV inhibition but was required for inhibition of EMCV

Pig (Porcine) Guanylate Binding Protein 2, Interferon-Inducible (GBP2) interaction partners

  1. cDNA sequences were cloned and the genomic structure of porcine GBP1 (show GBP1 Proteins) (poGBP1) and GBP2 (poGBP2), was analyzed.

Guanylate Binding Protein 2, Interferon-Inducible (GBP2) Protein Profile

Protein Summary

Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.

Gene names and symbols associated with GBP2

  • GTP binding protein 2 (gtpbp2)
  • GTP binding protein 2 (GTPBP2)
  • GTP binding protein 2 (Gtpbp2)
  • guanylate binding protein 2 (Gbp2)
  • guanylate binding protein 2, interferon-inducible (gbp2)
  • guanylate binding protein 2, interferon-inducible (GBP2)
  • guanylate binding protein 2, interferon-inducible (Gbp2)
  • si:ch211-151i8.2 protein
  • si:dkeyp-34c12.3 protein

Protein level used designations for GBP2

GTP-binding protein 2 , GTP-binding-like protein 2 , GBP-2 , guanine nucleotide-binding protein 2 , guanylate nucleotide binding protein 2 , interferon-induced guanylate-binding protein 2 , mGBP-2 , mGBP2 , isoprenylated 67 kDa protein , p67

GENE ID SPECIES
100101330 Xenopus laevis
54676 Homo sapiens
481818 Canis lupus familiaris
513605 Bos taurus
56055 Mus musculus
363195 Rattus norvegicus
570143 Danio rerio
14469 Mus musculus
779422 Xenopus laevis
2634 Homo sapiens
100153137 Sus scrofa
514143 Bos taurus
171164 Rattus norvegicus
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