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anti-Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3) Antibodies

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3, catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide (NO) and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM, Mar 2008].. Additionally we are shipping GUCY1B3 Proteins (5) and GUCY1B3 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GUCY1B3 2983 Q02153
GUCY1B3 54195 O54865
GUCY1B3 25202 P20595
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Top anti-GUCY1B3 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GUCY1B3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101921 concentration 5 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Rat Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$405.17
Details
Human Rabbit Un-conjugated IHC (p) Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN1804019 concentration 10 µg/mL. Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN1804019 concentration 10 µg/mL. 250 μL Log in to see 8 to 10 Days
$451.00
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of GUCY1B3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of GUCY1B3 expression in HEK293T (A), mouse kidney (B), rat kidney (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details

GUCY1B3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) , , ,


Top referenced anti-GUCY1B3 Antibodies

  1. Human Polyclonal GUCY1B3 Primary Antibody for EIA, WB - ABIN360701 : Lucas, Pitari, Kazerounian, Ruiz-Stewart, Park, Schulz, Chepenik, Waldman: Guanylyl cyclases and signaling by cyclic GMP. in Pharmacological reviews 2000 (PubMed)
    Show all 4 references for ABIN360701

  2. Human Polyclonal GUCY1B3 Primary Antibody for EIA, IHC (p) - ABIN493446 : Wedel, Garbers: Guanylyl cyclases: approaching year thirty. in Trends in endocrinology and metabolism: TEM 2008 (PubMed)
    Show all 3 references for ABIN493446

  3. Cow (Bovine) Polyclonal GUCY1B3 Primary Antibody for WB - ABIN2782430 : Mateos-Cáceres, Garcia-Cardoso, Lapuente, Zamorano-León, Sacristán, de Prada, Calahorra, Macaya, Vela-Navarrete, López-Farré: Soluble guanylate cyclase beta1-subunit expression is increased in mononuclear cells from patients with erectile dysfunction. in International journal of impotence research 2006 (PubMed)

More Antibodies against GUCY1B3 Interaction Partners

Human Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3) interaction partners

  1. The kinetics of heme loss from oxidized sGC (show SGCB Antibodies) was monitored by a new method based on the heme group de-quenching the fluorescence of FlAsH-EDT2.

  2. Dynamic interplay between hsp90 (show HSP90 Antibodies), apo (show C9orf3 Antibodies)-sGC (show SGCB Antibodies)-beta1, and sGC (show SGCB Antibodies)-alpha1 in response to NO is unprecedented and represent new steps by which cells can modulate the heme content and activity of sGC (show SGCB Antibodies) for signaling cascades.

  3. Gene expression in dendritic cells of CCL5 (show CCL5 Antibodies) and CXCL5 (show CXCL5 Antibodies) as well as TIMP1 (show TIMP1 Antibodies) and GUCY1B3 showed a significant increase within the first 4 days after trauma.

  4. The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclase

  5. We concluded that the alpha-subunit (show POLG Antibodies) and the beta(1)(191-619) domain exert structural strains on the heme domain.

  6. Data show that show that it is possible to directly monitor the sGC (show SGCB Antibodies) haem oxidation state in intact cells. By inserting the TC motif into the coding sequence of the beta1 subunit of sGC (show SGCB Antibodies) in transiently transfected Chinese hamster ovary cells.

  7. recombinant soluble guanylate cyclase (sGC (show SGCB Antibodies)) beta1 subunit and truncated N-terminal fragments expressed in E. coli; studied interaction between NO and sGC (show SGCB Antibodies) and schematic mechanism was proposed; study provides insights into structure and NO-binding of sGC (show SGCB Antibodies)

  8. Results show that NOGCbeta1 and GC-A (show NPR1 Antibodies) interact and that NOGCbeta1 regulates atrial natriuretic peptide (show NPPA Antibodies) signaling in HK-2 (show HK2 Antibodies) cells.

  9. Although soluble guanylate cyclase(sGC (show SGCB Antibodies)) beta1-subunit expression was increased in mononuclear cells from patients with erectile dysfunction, the sGC (show SGCB Antibodies) activity was reduced

Pig (Porcine) Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3) interaction partners

  1. expression of sGC (show NPR1 Antibodies) beta(1)-subunit in pulmonary arteries increased with postnatal age both at the level of mRNA and protein

Cow (Bovine) Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3) interaction partners

  1. These results suggest a means by which the hsp90beta (show HSP90AB1 Antibodies) interaction could prevent apo (show C9orf3 Antibodies)-sGCbeta1 from associating with its partner sGCalpha1 subunit while enabling structural changes to assist heme insertion into the H-NOX domain.

  2. We concluded that the alpha-subunit (show POLG Antibodies) and the beta(1)(191-619) domain exert structural strains on the heme domain.

Mouse (Murine) Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3) interaction partners

  1. Apo (show C9orf3 Antibodies)-sGC (show NPR1 Antibodies) mice expressing haem-free sGC (show NPR1 Antibodies) are viable and develop hypertension. The haemodynamic effects of NO are abolished, but those of the sGC (show NPR1 Antibodies) activator cinaciguat are enhanced.

  2. sGC (show NPR1 Antibodies) and cGMP-dependent signaling are necessary and sufficient for HNO-induced vasodilation in vivo but are not required for positive inotropic action.

  3. Deletion of GCbeta1 specifically in smooth muscle cells abolishes NO-induced corpus cavernosum relaxation but does not lead to infertility.

  4. A VASP (show VASP Antibodies) to Rac (show AKT1 Antibodies) to soluble guanylyl cyclase negative feedback loop limited cGMP production, thereby regulating adipogenesis and energy homeostasis.

  5. These data suggests a novel physiological role for PDE5 (show PDE5A Antibodies) in restricting the effects of NOS3 (show NOS3 Antibodies)/sGC (show NPR1 Antibodies)/PKG (show PRKG1 Antibodies) signaling pathway to modulating beta-AR stimulated I(Ca), while limiting effects on cardiac contraction.[sGC (show NPR1 Antibodies)]

  6. Pressure overload results in translocation of sGC (show NPR1 Antibodies) out of membrane microdomains, depressing NO/heme-dependent activation in the heart, consistent with enhanced oxidation.

  7. Important roles of sGC (show NPR1 Antibodies) in stimulating platelet activation and in vivo thrombosis and hemostasis.

  8. findings identify a crucial role of the NO/sGCalpha1beta1/cGMP pathway in modulating lymphatic vessel function [soluble guanylate cyclase alpha1beta1]

  9. Knockout of GCbeta1 completely disrupts the NO/cGMP signaling cascade and provides evidence for the unique role of NO-GC as NO receptor.

  10. cGMP generated by sGC (show NPR1 Antibodies)(alpha)(1)beta(1) protects against cardiac dysfunction and mortality in murine inflammatory shock models

GUCY1B3 Antigen Profile

Protein Summary

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3, catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide (NO) and nitrovasodilator drugs (Zabel et al., 1998

Gene names and symbols associated with GUCY1B3

  • guanylate cyclase 1, soluble, beta 3 (GUCY1B3) antibody
  • guanylate cyclase 1, soluble, beta 3 (gucy1b3) antibody
  • guanylate cyclase, soluble, beta 1 (Gycbeta1) antibody
  • soluble guanylyl cyclase beta subunit (gucy1b3) antibody
  • guanylate cyclase 1, soluble, beta 3 (Gucy1b3) antibody
  • AMGC1 antibody
  • AmsGC-beta1 antibody
  • AmsGCbeta1 antibody
  • GB20021 antibody
  • GC-S-beta-1 antibody
  • GC-SB3 antibody
  • GCbeta1 antibody
  • GUC1B3 antibody
  • GUCB3 antibody
  • GUCSB3 antibody
  • Gucy1b1 antibody
  • gucy1b3 antibody
  • SGC antibody
  • SGCB1 antibody

Protein level used designations for GUCY1B3

guanylate cyclase 1, soluble, beta 3 , guanylate cyclase soluble subunit beta-1-like , guanylate cyclase soluble subunit beta-1 , soluble guanylyl cyclase beta subunit , GCS-beta-1 , GCS-beta-3 , guanylate cyclase soluble subunit beta-3 , soluble guanylate cyclase small subunit , soluble guanylate cyclase 1 beta 3 , soluble guanylyl cyclase beta 1 subunit , NO-sensitive GC beta 1 subunit , nitric oxide-sensitive guanylyl cyclase beta 1 subunit , NO-sensitive guanylyl cyclase beta 1 subunit , beta 1 sGC , soluble guanylate cyclase beta-1 subunit , guanylate cyclase, soluble, beta 1

GENE ID SPECIES
422408 Gallus gallus
461565 Pan troglodytes
100379900 Xenopus (Silurana) tropicalis
100395297 Callithrix jacchus
100424944 Macaca mulatta
408880 Apis mellifera
100049178 Oryzias latipes
100583335 Nomascus leucogenys
432281 Xenopus laevis
2983 Homo sapiens
553102 Canis lupus familiaris
444999 Sus scrofa
282433 Bos taurus
54195 Mus musculus
25202 Rattus norvegicus
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