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Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) Proteins (GUCY2C)

guanylyl cyclase\; functions as receptor for heat-stable enterotoxin responsible for acute diarrhea [RGD, Feb 2006].. Additionally we are shipping GUCY2C Antibodies (29) and GUCY2C Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GUCY2C 100359629  
GUCY2C 14917 Q3UWA6
GUCY2C 2984 P25092
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Top GUCY2C Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,129.50
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,138.67
Details
Yeast Guinea Pig His tag   1 mg Log in to see 56 to 66 Days
$3,138.67
Details

GUCY2C Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) Interaction Partners

Mouse (Murine) Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) interaction partners

  1. Findings show how caloric suppression of the guanylin (show GUCA2A Proteins)-GUCY2C signaling axis links obesity to negation of a universal tumor suppressor pathway in colorectal cancer.

  2. The GC-C signaling pathway blunts colonic mucosal inflammation that is initiated by systemic cytokine burst or loss of mucosal immune cell immunosuppression.

  3. GC-C signaling is an essential component of host defense during murine enteric infection by reducing bacterial load and preventing systemic dissemination of attaching/effacing-lesion forming bacterial pathogens such as C. rodentium.

  4. Intestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21.

  5. guanylate cyclase-C

  6. GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT (show AKT1 Proteins)-dependent intestinal barrier integrity

  7. The role for GUCY2C-directed CD8 (show CD8A Proteins)(+) T cells targeting specific epitopes in antitumor efficacy.

  8. Data show that silencing of GUCY2C in mice disrupts satiation, resulting in hyperphagia and subsequent obesity and metabolic syndrome.

  9. a novel role for GC-C signaling in facilitating mucosal wounding and inflammation, and further suggest that this may be mediated, in part, through control of RELMbeta (show RETNLB Proteins) production

  10. midbrain dopamine neurons express GC-C; GC-C activation potentiates excitatory response mediated by glutamate (show GRIN1 Proteins) and acetylcholine receptors via activity of PKG (show PRKG1 Proteins); GC-C knockout mice exhibit hyperactivity and attention deficit

Human Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) interaction partners

  1. Findings show how caloric suppression of the guanylin (show GUCA2A Proteins)-GUCY2C signaling axis links obesity to negation of a universal tumor suppressor pathway in colorectal cancer.

  2. Data show that individuals affected with meconium ileus (MI) had either homozygous or compound heterozygous variants in enterotoxin receptor GUCY2C.

  3. High guanylyl cyclase C expression is associated with colon cancer recurrence.

  4. Transmission disequilibrium tests (TDT (show DNTT Proteins)), case-control studies and quantitative analyses indicated association between GUC2C with Attention-deficit/hyperactivitydisorder and its core symptoms.

  5. Intestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21 (show CDKN1A Proteins).

  6. GUCY2C signaling constitutes a direct link between the initiation of colorectal cancer and the induction of its associated desmoplastic stromal niche.

  7. Data show that lower survival (OS) and disease-free survival (DFS (show FST Proteins)) rates were significantly associated with guanylate cyclase C (GCC) and CK20 (show KRT20 Proteins) mRNA levels.

  8. Interaction with VIP36 (show LMAN2 Proteins) is dependent on glycosylation at the same sites that allow GC-C to fold and bind ligand.

  9. GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT (show AKT1 Proteins)-dependent intestinal barrier integrity

  10. Mutations in GUCY2C were associated with the Meconium ileus phenotype. downregulation of GUCY2C leads to a cystic fibrosis (show S100A8 Proteins)-like intestinal phenotype.

GUCY2C Protein Profile

Protein Summary

guanylyl cyclase\; functions as receptor for heat-stable enterotoxin responsible for acute diarrhea

Gene names and symbols associated with GUCY2C

  • guanylate cyclase 2c (LOC100359629)
  • guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C)
  • guanylate cyclase 2C (heat stable enterotoxin receptor) (gucy2c)
  • guanylyl cyclase C (GCC)
  • guanylate cyclase 2C (Gucy2c)
  • guanylate cyclase 2c (Gucy2c)
  • AI893437 protein
  • DIAR6 protein
  • GC-C protein
  • Gcc protein
  • GUC2C protein
  • Gucy2c protein
  • gucy2c-A protein
  • MECIL protein
  • MUCIL protein
  • STAR protein

Protein level used designations for GUCY2C

guanylate cyclase 2c , heat stable enterotoxin receptor , heat-stable enterotoxin receptor , guanylate cyclase 2C , guanylate cyclase 2C (heat stable enterotoxin receptor) , heat-stable enterotoxin receptor-like , guanylyl cyclase C , GC-C , Guanylate cyclase 2C (heat stable enterotoxin receptor) , STA receptor , intestinal guanylate cyclase , hSTAR

GENE ID SPECIES
100359629 Rattus norvegicus
282244 Bos taurus
378662 Xenopus laevis
417968 Gallus gallus
473375 Pan troglodytes
486671 Canis lupus familiaris
699191 Macaca mulatta
100406002 Callithrix jacchus
100460918 Pongo abelii
100563369 Anolis carolinensis
100594944 Nomascus leucogenys
100008740 Oryctolagus cuniculus
25711 Rattus norvegicus
14917 Mus musculus
100135536 Cavia porcellus
2984 Homo sapiens
397193 Sus scrofa
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