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anti-Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D) Antibodies

GUCY2D encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Additionally we are shipping Guanylate Cyclase 2D, Membrane (Retina-Specific) Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GUCY2D 3000 Q02846
GUCY2D    
GUCY2D    
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Top anti-Guanylate Cyclase 2D, Membrane (Retina-Specific) Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of Ramos cells using GUCY2D / GUCY2D / RETGC1 Antibody (Center) Cat..-No AP51984PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue reacted with GUCY2D / GUCY2D / RETGC1 Antibody (Center) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB GUCY2D Antibody (Center)  western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the GUCY2D antibody detected the GUCY2D protein (arrow). GUCY2D Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GUCY2D Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged GUCY2D is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.73 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Biotin FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to GUCY2D on HeLa cell. [antibody concentration 10 ug/ml] Western Blot detection against Immunogen (37.73 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.1 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated FACS, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

GUCY2D Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Top referenced anti-Guanylate Cyclase 2D, Membrane (Retina-Specific) Antibodies

  1. Human Polyclonal GUCY2D Primary Antibody for WB - ABIN493348 : Birdsall, Hulme: Biochemical studies on muscarinic acetylcholine receptors. in Journal of neurochemistry 1976 (PubMed)
    Show all 3 references for ABIN493348

  2. Human Polyclonal GUCY2D Primary Antibody for EIA, FACS - ABIN952663 : Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: Dengue hemorrhagic fever is associated with polymorphisms in JAK1. in European journal of human genetics : EJHG 2010 (PubMed)
    Show all 2 references for ABIN952663

More Antibodies against Guanylate Cyclase 2D, Membrane (Retina-Specific) Interaction Partners

Human Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D) interaction partners

  1. Two novel mutations causing phenotypic LCA (show CLTA Antibodies) and Alstrom syndrome in Saudi patients from consanguineous families expand the genotypic spectrum of congenital retinal dystrophies.

  2. Data suggest that GCAP1 (guanylate cyclase activator 1A (show GUCA1A Antibodies); Mg2 (show MUC7 Antibodies)+ vs. Ca2 (show CA2 Antibodies)+) exhibits conformational changes in Ca2 (show CA2 Antibodies)+ switch helix that are important in activation of RetGC1; myristoylation of GCAP1 (show GUCA1A Antibodies) is important as well in attaining activator conformation.

  3. Gc1s/Gc1s phenotype variant of DBP (show GC Antibodies) and the unbound fraction of plasma RBP4 (show POLR2D Antibodies) may be considered as factors related with the incidence, and possibly the risk, of IR in CHC (show CLTC Antibodies) patients.

  4. Guanylate cyclase signaling pathway is down regulated in the pathogenesis of inflammatory bowel diseases.

  5. Studies indicate that mutations in retinal guanylate cylase-1 (GUCY2D) are associated with a leading cause of recessive Leber congenital amaurosis (LCA1).

  6. The GUCY2D mutations were frequent in Chinese families with autosomal dominant cone or cone-rod dystrophies. All mutations were found in exon 13.

  7. Dimerization domain of RETGC1 is an essential part of GCAP1 (show GUCA1A Antibodies) and GCAP2 (show GUCA1B Antibodies) binding interface.

  8. The GCAP1 and GCAP2 binding site(s) overlaps within the kinase homology and/or dimerization domains of retinal GC1.

  9. Cardiac fibrosis and the endogenous natriuretic peptide system were evaluated in end-stage heart failure to assess the anti-fibrotic actions of the dual GC-A (show NPR1 Antibodies)/-B activator.

  10. A deletion mutation in the GUCY2D gene is associated with Leber congenital amaurosis in a consanguineous Pakistani family.

Cow (Bovine) Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D) interaction partners

  1. The findings define a new regulatory mechanism of the ROS-GC system that affects visual transduction and is likely to affect the course of retinal diseases caused by cGMP toxicity.

  2. The coexpression of ROS-GC1 and its activators in spermatozoa suggests that the Ca(2+)-modulated ROS-GC1 transduction system may be a part of the fertilization machinery

  3. Mg(2 (show MCOLN1 Antibodies)+) binding to GCAPs is critical for setting the actual dynamic range of RetGC regulation by GCAPs at physiological levels of free Ca(2 (show CA2 Antibodies)+)

  4. The Tyr965-Asn981 region of rod outer segment membrane guanylate cyclase type 1 (ROS-GC1) houses both the structural and functional components that mediate guanylate cyclase activating protein type 2 (GCAP2 (show GUCA1B Antibodies)) regulation.

Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D) Antigen Profile

Protein Summary

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.

Gene names and symbols associated with GUCY2D

  • guanylate cyclase 2D, membrane (retina-specific) (GUCY2D) antibody
  • CORD5 antibody
  • CORD6 antibody
  • CYGD antibody
  • GUC1A4 antibody
  • GUC2D antibody
  • LCA antibody
  • LCA1 antibody
  • RCD2 antibody
  • retGC antibody
  • RETGC-1 antibody
  • ROS-GC1 antibody
  • ROSGC antibody

Protein level used designations for GUCY2D

ROS-GC , cone rod dystrophy 6 , guanylate cyclase 2D, retinal , retinal guanylyl cyclase 1 , rod outer segment membrane guanylate cyclase , GC-E , RETGC-1 , guanylate cyclase E

GENE ID SPECIES
3000 Homo sapiens
282245 Bos taurus
403863 Canis lupus familiaris
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