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Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D) ELISA Kits

GUCY2D encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Additionally we are shipping Guanylate Cyclase 2D, Membrane (Retina-Specific) Antibodies (43) and Guanylate Cyclase 2D, Membrane (Retina-Specific) Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human GUCY2D GUCY2D 3000 Q02846
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More ELISA Kits for Guanylate Cyclase 2D, Membrane (Retina-Specific) Interaction Partners

Human Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D) interaction partners

  1. Two novel mutations causing phenotypic LCA (show CLTA ELISA Kits) and Alstrom syndrome in Saudi patients from consanguineous families expand the genotypic spectrum of congenital retinal dystrophies.

  2. Data suggest that GCAP1 (guanylate cyclase activator 1A (show GUCA1A ELISA Kits); Mg2 (show MUC7 ELISA Kits)+ vs. Ca2 (show CA2 ELISA Kits)+) exhibits conformational changes in Ca2 (show CA2 ELISA Kits)+ switch helix that are important in activation of RetGC1; myristoylation of GCAP1 (show GUCA1A ELISA Kits) is important as well in attaining activator conformation.

  3. Gc1s/Gc1s phenotype variant of DBP (show GC ELISA Kits) and the unbound fraction of plasma RBP4 (show POLR2D ELISA Kits) may be considered as factors related with the incidence, and possibly the risk, of IR in CHC (show CLTC ELISA Kits) patients.

  4. Guanylate cyclase signaling pathway is down regulated in the pathogenesis of inflammatory bowel diseases.

  5. Studies indicate that mutations in retinal guanylate cylase-1 (GUCY2D) are associated with a leading cause of recessive Leber congenital amaurosis (LCA1).

  6. The GUCY2D mutations were frequent in Chinese families with autosomal dominant cone or cone-rod dystrophies. All mutations were found in exon 13.

  7. Dimerization domain of RETGC1 is an essential part of GCAP1 (show GUCA1A ELISA Kits) and GCAP2 (show GUCA1B ELISA Kits) binding interface.

  8. The GCAP1 and GCAP2 binding site(s) overlaps within the kinase homology and/or dimerization domains of retinal GC1.

  9. Cardiac fibrosis and the endogenous natriuretic peptide system were evaluated in end-stage heart failure to assess the anti-fibrotic actions of the dual GC-A (show NPR1 ELISA Kits)/-B activator.

  10. A deletion mutation in the GUCY2D gene is associated with Leber congenital amaurosis in a consanguineous Pakistani family.

Cow (Bovine) Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D) interaction partners

  1. The findings define a new regulatory mechanism of the ROS-GC system that affects visual transduction and is likely to affect the course of retinal diseases caused by cGMP toxicity.

  2. The coexpression of ROS-GC1 and its activators in spermatozoa suggests that the Ca(2+)-modulated ROS-GC1 transduction system may be a part of the fertilization machinery

  3. Mg(2 (show MCOLN1 ELISA Kits)+) binding to GCAPs is critical for setting the actual dynamic range of RetGC regulation by GCAPs at physiological levels of free Ca(2 (show CA2 ELISA Kits)+)

  4. The Tyr965-Asn981 region of rod outer segment membrane guanylate cyclase type 1 (ROS-GC1) houses both the structural and functional components that mediate guanylate cyclase activating protein type 2 (GCAP2 (show GUCA1B ELISA Kits)) regulation.

Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D) Antigen Profile

Antigen Summary

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.

Gene names and symbols associated with GUCY2D

  • guanylate cyclase 2D, membrane (retina-specific) (GUCY2D) antibody
  • CORD5 antibody
  • CORD6 antibody
  • CYGD antibody
  • GUC1A4 antibody
  • GUC2D antibody
  • LCA antibody
  • LCA1 antibody
  • RCD2 antibody
  • retGC antibody
  • RETGC-1 antibody
  • ROS-GC1 antibody
  • ROSGC antibody

Protein level used designations for GUCY2D

ROS-GC , cone rod dystrophy 6 , guanylate cyclase 2D, retinal , retinal guanylyl cyclase 1 , rod outer segment membrane guanylate cyclase , GC-E , RETGC-1 , guanylate cyclase E

3000 Homo sapiens
282245 Bos taurus
403863 Canis lupus familiaris
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