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Guanylate Cyclase Activator 2B (Uroguanylin) Proteins (GUCA2B)

GUCA2B encodes a member of the guanylin family, and is expressed in the stomach and intestine. Additionally we are shipping GUCA2B Antibodies (55) and GUCA2B Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat GUCA2B GUCA2B 64055 P70668
Mouse GUCA2B GUCA2B 14916 O09051
GUCA2B 2981 Q16661
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Top GUCA2B Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 10 μg Log in to see 15 to 19 Days
$314.16
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 2 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Human Human Un-conjugated 20 μg Log in to see 9 to 11 Days
$785.40
Details

GUCA2B Proteins by Origin and Source

Origin Expressed in
Human ,

More Proteins for Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B) Interaction Partners

Mouse (Murine) Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B) interaction partners

  1. UGN exerts its inhibitory activity on the prendrin gene promoter likely via heat shock factor 1 action at a defined heat shock element site.

  2. findings establish a role for uroguanylin in an enteric-renal communication axis as well as a fundamental principle of this axis in the maintenance of salt homeostasis in vivo

  3. act on the mouse kidney, in part, through a cGMP-dependent, GC-C (show GUCY2C Proteins)-independent mechanism, causing significant natriuresis by renal tubular processes.

  4. existence of two signaling pathways for guanylin (show GUCA2A Proteins) peptides in principal cells of mouse cortical collecting duct of kidney

  5. Role for uroguanylin in fluid homeostasis and as an integral component of a signaling mechanism that mediates changes in Na excretion in response to an enteral salt loading.

Human Guanylate Cyclase Activator 2B (Uroguanylin) (GUCA2B) interaction partners

  1. Uroguanylin concentrations are increased in patients with chronic renal failure, nephrotic syndrome, or those on dialysis.

GUCA2B Protein Profile

Protein Summary

This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues.

Gene names and symbols associated with GUCA2B

  • guanylate cyclase activator 2B (uroguanylin) (GUCA2B)
  • guanylate cyclase activator 2B (Guca2b)
  • guanylate cyclase activator 2b (retina) (Guca2b)
  • AV066530 protein
  • GCAP-II protein
  • Gcap2 protein
  • GUCA2B protein
  • UGN protein

Protein level used designations for GUCA2B

guanylate cyclase activator 2B (uroguanylin) , guanylate cyclase activator 2B , guanylate cyclase activator 2b (retina) , uroguanylin , granule cell antiserum positive 2 , guanylyl cyclase activating peptide II

GENE ID SPECIES
469301 Pan troglodytes
699525 Macaca mulatta
515664 Bos taurus
64055 Rattus norvegicus
14916 Mus musculus
100135535 Cavia porcellus
2981 Homo sapiens
100301561 Sus scrofa
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