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Essential for normal spermatogenesis and male fertility. Additionally we are shipping H1 Histone Family, Member N, Testis-Specific Antibodies (3) and H1 Histone Family, Member N, Testis-Specific Proteins (3) and many more products for this protein.
h-HANP1 is expressed in the testes and its genomic construct also intronless as mouse Hanp1. We found that the h-HANP1 coding region have 5 single-nucleotide polymorphisms in Japanese men.
H1T2 is a protein required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis.
HANP1/H1T2 is essential for nuclear formation in functional spermatozoa and is specifically involved in the replacement of histones with protamines during spermiogenesis
H1T2 can be a useful molecular marker revealing chromatin disorganization in spermatids.
Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone- protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1 (By similarity).
, haploid germ cell-specific nuclear protein 1
, histone H1t2
, testis-specific H1 histone
, expressed in haploid spermatids during spermiogenesis, specifically at the apical pole of round and elongating spermatids