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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Additionally we are shipping H1 Histone Family, Member X Proteins (2) and many more products for this protein.
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Human Polyclonal H1FX Primary Antibody for WB - ABIN657653
Warneboldt, Haller, Horstmann, Danner, Füzesi, Doenecke, Happel: Histone H1x is highly expressed in human neuroendocrine cells and tumours. in BMC cancer 2009
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comparison of primary aa sequence with other human H1 subtypes, and H1x from different species, generation of specific antibody, expression in different cell lines
These results suggest that the differential localization of H1x provides a mechanism for a control of H1x activity by means of shuttling between nuclear subcompartments instead of a controlled turnover of the protein.
study concludes that the high expression of histone H1x in neuroendocrine tumours is probably due to the abundance of this protein in the cells from which these tumours originate
expressed on the membranes of phagocytic cells, NK cells, and APCs (show APCS Antibodies) as well as in the granules of macrophages; may participate as a bifunctional protein
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H1 family.
, H1 histone family, member X