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The protein encoded by H19 is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide.
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Human H19 ELISA Kit for Sandwich ELISA - ABIN416970
Awojoodu, Keegan, Lane, Zhang, Lynch, Platt, Botchwey: Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD. in Blood 2014
ASM (show SMPD1 ELISA Kits) activation may be involved in the pathophysiology of Kawasaki disease
These results indicate that increased EGR1 (show EGR1 ELISA Kits)/3 and ASMase (show SMPD1 ELISA Kits) expression play an important role in cellular ceramide increase by RSV treatment.
The results of this study suggested that disruptive mutations in SMPD1 (show SMPD1 ELISA Kits) constitute a risk factor for parkindon disease.
This is the first evidence that supports the possibility that sphingolipid metabolism is affected via the induction of ASMase (show SMPD1 ELISA Kits) by the Nrf2 (show GABPA ELISA Kits) pathway.
ASM (show SMPD1 ELISA Kits) has a pivotal role in adaptive immune T-cell responses.
Patterns of alternatively spliced SMPD1 (show SMPD1 ELISA Kits) transcripts are significantly different in patients with systemic inflammatory response syndrome and severe sepsis/septic shock compared to control subjects allowing discrimination of respective disease entity.
The mechanisms by which pyocyanin induces the release of mitochondrial ROS (show ROS1 ELISA Kits) and by which ROS (show ROS1 ELISA Kits) induce neutrophil death via mitochondrial acid sphingomyelinase (show SMPD1 ELISA Kits) was identified.
Results show four novel mutations in SMPD1 (show SMPD1 ELISA Kits) in Iranian patients with type A or B Niemann-Pick disease extending the genotypic spectrum of the disease.
The relationship between autophagy and A-SMase (show SMPD1 ELISA Kits). [Review]
Data suggest ASM (acid sphingomyelinase (show SMPD1 ELISA Kits)) activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2 (show NPC2 ELISA Kits) (Niemann Pick protein type C2); hydrolysis of sphingomyelin by ASM (show SMPD1 ELISA Kits) may be crucial for endosomal lipid degradation/sorting.
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
, sphingomyelin phosphodiesterase