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H2.0-Like Homeobox (HLX) ELISA Kits

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Additionally we are shipping HLX Antibodies (53) and HLX Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human HLX HLX 3142 Q14774
Anti-Mouse HLX HLX 15284 Q61670
Anti-Rat HLX HLX 364069 A0JPN1
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More ELISA Kits for HLX Interaction Partners

Zebrafish H2.0-Like Homeobox (HLX) interaction partners

  1. Hlx1 selectively marks sprouting endothelial cells during zebrafish development.Hlx1 is required for intersegmental vessel angiogenesis in zebrafish embryos.Hlx1 cell-autonomously maintains endothelial stalk cell potential.

Human H2.0-Like Homeobox (HLX) interaction partners

  1. Studies have identified HLX as a novel key transcription factor involved in the regulation of early hematopoiesis and AML (show RUNX1 ELISA Kits) pathogenesis.

  2. The expression levels of Hlx, T-bet, and IFN-gamma (show IFNG ELISA Kits) were significantly decreased.

  3. Data suggest that HLX1 is downstream mediator of hepatocyte growth factor- (HGF (show HGF ELISA Kits)-) induced cell survival, cell proliferation, and invasive properties of trophoblast cells; thus, both HGF (show HGF ELISA Kits) and HLX1 appear to be involved in normal placental development.

  4. This study identifies HLX as a key regulator in immature hematopoietic and leukemia cells and as a prognostic marker and therapeutic target in acute myeloid leukemia (show BCL11A ELISA Kits).

  5. This study investigated the influence of TBX21 and HLX1 single nucleotide polymorphisms (SNPs), which have previously been shown to be associated with asthma, on T(H)1/T(H)2 lineage cytokines at birth.

  6. a functional polymorphism in HLX in combination with the TBX21 polymorphism is also associated with the prognosis of Graves' disease.

  7. These data suggest that HLX may function to balance attractive with repulsive vessel guidance by up-regulating UNC5B (show UNC5B ELISA Kits) and to down-modulate sprouting under normoxic conditions.

  8. HLX is a mediator of HGF/c-met-dependent trophoblast migration but is not involved in the regulation of trophoblast invsion.

  9. Cell cycle regulatory genes RB1 (show RB1 ELISA Kits), MYC (show MYC ELISA Kits), CCNB1 (show CCNB1 ELISA Kits), ELK1 (show ELK1 ELISA Kits), JUN (show JUN ELISA Kits), and CDKN1C (show CDKN1C ELISA Kits), which control important trophoblast cell functions, are targets of HLX.

  10. Decreased HLX1 expression is associated with idiopathic fetal growth restriction

Mouse (Murine) H2.0-Like Homeobox (HLX) interaction partners

  1. methyl-CpG-binding domain protein 2 (MBD2 (show MBD2 ELISA Kits)), an epigenetic regulator, controls autoimmunity and EAE through T-bet/Hlx.

  2. Hlx regulates sprouting in vitro, but its role in sprouting is nonessential in vivo. HLX is regulated by shear stress and a subtle defect in vascular remodeling is present in knockout embryos.

  3. Results shown that over-expressed Hlx in DC2.4 up-regulated the transcription and expression of IFN-gamma, increased the expression of maturation makers including CD40, CD80, CD86, MHC-I and MHC-II

  4. Transient over-expression of Hlx in DC2.4 promotes DC2.4 maturation and up-regulates IL-12, IL-10 and TGF-beta expression. H1x modified DC2.4 cells seem to function as regulatory dendritic cells

  5. Hlx expression in activated NK cells temporally controls and limits the monokine-induced production of interferon-gamma (show IFNG ELISA Kits)

HLX Antigen Profile

Antigen Summary

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).

Gene names and symbols associated with H2.0-Like Homeobox (HLX) ELISA Kits

  • H2.0-like homeobox (BRAFLDRAFT_290377) antibody
  • H2.0-like homeo box 1 (Drosophila) (hlx1) antibody
  • H2.0-like homeobox (HLX) antibody
  • H2.0-like homeobox (Hlx) antibody
  • fa28a07 antibody
  • HB24 antibody
  • Hlx1 antibody
  • wu:fa28a07 antibody
  • zgc:76923 antibody

Protein level used designations for H2.0-Like Homeobox (HLX) ELISA Kits

H2.0-like homeobox , H2.0-like homeobox protein , H2.0-like homeo box 1 , H2.0-like homeo box-1 , H2.0-like homeobox 1 , homeobox protein HB24 , homeobox protein HLX1

7217998 Branchiostoma floridae
327096 Danio rerio
3142 Homo sapiens
519165 Bos taurus
15284 Mus musculus
364069 Rattus norvegicus
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