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H3F3AP4 encodes a core component of the exosome.
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Human Monoclonal H3F3AP4 Primary Antibody for IHC (fro) - ABIN966727
Murao, Epstein, Clevenger, Huberman: Expression of maturation-specific nuclear antigens in differentiating human myeloid leukemia cells. in Cancer research 1985
association of hCsl4p with the exosome is mediated by protein-protein interactions with hRrp42p (show EXOSC7 Antibodies) and hRrp46p (show EXOSC5 Antibodies)
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase (show PNPT1 Antibodies)-like ring.
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
3'-5' exoribonuclease CSL4 homolog
, CSL4 exosomal core protein homolog
, exosomal core protein CSL4
, exosome complex component CSL4
, homolog of yeast exosomal core protein CSL4