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HAUS6 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. Additionally we are shipping HAUS Augmin-Like Complex, Subunit 6 Proteins (3) and many more products for this protein.
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Hice1 (show HAUS8 Antibodies) and hDgt6 are core components of distinct augmin sub-complexes.
Results suggest that an important mitotic function for gamma-tubulin (show TUBG1 Antibodies) may lie within the spindle, where augmin (Dgt2-6; FAM29A) and gamma-tubulin (show TUBG1 Antibodies) function cooperatively to amplify the number of microtubules.
FAM29A promotes microtubule amplification via recruitment of the NEDD1 (show NEDD1 Antibodies)-gamma-tubulin (show TUBG1 Antibodies) complex to the mitotic spindle.
The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in microtubule attachment to the kinetochore and central spindle formation. This protein may have a role in efficient chromosome congression and segregation by promoting microtubule-dependent microtubule amplification. Pseudogenes of this gene are located on chromosomes 7 and 20. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
HAUS augmin-like complex subunit 6
, dim gamma-tubulin homolog
, family with sequence similarity 29, member A