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anti-HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1) Antibodies

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HECW1 23072 Q76N89
Anti-Mouse HECW1 HECW1 94253 Q8K4P8
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Top anti-HECW1 Antibodies at antibodies-online.com

Showing 1 out of 2 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) 0.1 mL Log in to see 8 to 11 Days
$483.66
Details

HECW1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human


More Antibodies against HECW1 Interaction Partners

Human HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1) interaction partners

  1. Ndel1 (show NDEL1 Antibodies) acts as a novel upstream regulator of the trichoplein-Aurora A (show AURKA Antibodies) pathway to inhibit primary cilia assembly.

  2. Ndel1 (show NDEL1 Antibodies) regulates Dyn2 (show DNM2 Antibodies) GTPase (show RACGAP1 Antibodies) activity and impacts GluR1 (show GRIA1 Antibodies)-containing membranes distribution in a manner reminiscent of Dyn2 (show DNM2 Antibodies).

  3. These findings suggest that the human NEDL1 transgenic mice might develop Amyotrophic lateral sclerosis-like symptoms, showing signs of motor abnormalities, accompanied with significant reduction in muscle strength.

  4. These findings suggest that RNF43 (show RNF43 Antibodies) is associated with p53 (show TP53 Antibodies)-mediated apoptosis in collaboration with NEDL1 in colorectal carcinogenesis.

  5. interaction among misfolded SOD1 (show SOD1 Antibodies), NEDL1, translocon-associated protein-delta (show SSR4 Antibodies), and Dishevelled-1 (show DVL1 Antibodies) forms a ubiquitinated protein complex that is included in potentially cytotoxic protein aggregates

  6. functional interaction of NEDL1 with p53 (show TP53 Antibodies) might contribute to the induction of apoptosis in cancerous cells bearing wild-type p53 (show TP53 Antibodies).

Mouse (Murine) HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1) interaction partners

  1. Ndel1 (show NDEL1 Antibodies) acts as a novel upstream regulator of the trichoplein-Aurora A (show AURKA Antibodies) pathway to inhibit primary cilia assembly.

HECW1 Antigen Profile

Protein Summary

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.

Gene names and symbols associated with HECW1

  • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (HECW1) antibody
  • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (Hecw1) antibody
  • 9330116H24Rik antibody
  • AV273951 antibody
  • E130207I19Rik antibody
  • Nedl1 antibody

Protein level used designations for HECW1

E3 ubiquitin-protein ligase HECW1 , HECT type E3 ubiquitin ligase , HECT, C2 and WW domain-containing protein 1 , NEDD4-like E3 ubiquitin-protein ligase 1 , NEDD4-like ubiquitin-protein ligase 1 , mNEDL1

GENE ID SPECIES
23072 Homo sapiens
94253 Mus musculus
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