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E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Additionally we are shipping and many more products for this protein.
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Ndel1 (show NDEL1 Antibodies) acts as a novel upstream regulator of the trichoplein-Aurora A (show AURKA Antibodies) pathway to inhibit primary cilia assembly.
Ndel1 (show NDEL1 Antibodies) regulates Dyn2 (show DNM2 Antibodies) GTPase (show RACGAP1 Antibodies) activity and impacts GluR1 (show GRIA1 Antibodies)-containing membranes distribution in a manner reminiscent of Dyn2 (show DNM2 Antibodies).
These findings suggest that the human NEDL1 transgenic mice might develop Amyotrophic lateral sclerosis-like symptoms, showing signs of motor abnormalities, accompanied with significant reduction in muscle strength.
These findings suggest that RNF43 (show RNF43 Antibodies) is associated with p53 (show TP53 Antibodies)-mediated apoptosis in collaboration with NEDL1 in colorectal carcinogenesis.
interaction among misfolded SOD1 (show SOD1 Antibodies), NEDL1, translocon-associated protein-delta (show SSR4 Antibodies), and Dishevelled-1 (show DVL1 Antibodies) forms a ubiquitinated protein complex that is included in potentially cytotoxic protein aggregates
functional interaction of NEDL1 with p53 (show TP53 Antibodies) might contribute to the induction of apoptosis in cancerous cells bearing wild-type p53 (show TP53 Antibodies).
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
E3 ubiquitin-protein ligase HECW1
, HECT type E3 ubiquitin ligase
, HECT, C2 and WW domain-containing protein 1
, NEDD4-like E3 ubiquitin-protein ligase 1
, NEDD4-like ubiquitin-protein ligase 1