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HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 2 Proteins (HECW2)

E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Additionally we are shipping HECW2 Antibodies (47) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat HECW2 HECW2 316395  
HECW2 57520 Q9P2P5
HECW2 329152 Q6I6G8
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Top HECW2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

HECW2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 2 (HECW2) Interaction Partners

Human HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 2 (HECW2) interaction partners

  1. Low HECW2 expression is associated with cervical cancer.

  2. NEDL2 is a novel substrate of APC (show APC Proteins)/C-Cdh1 (show CDH1 Proteins) as cells exit mitosis and functions as a regulator of the metaphase to anaphase transition

Mouse (Murine) HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 2 (HECW2) interaction partners

  1. NEDL2 positively regulates enteric neural precursor proliferation through the GDNF (show GDNF Proteins)/Akt (show AKT1 Proteins) signaling pathway.

  2. Grk2 (show ADRBK1 Proteins) phosphorylates the C terminus of the Na-channel beta subunit (show POLG Proteins) and renders the channels insensitive to inhibition by Nedd4-2 (show NEDD4L Proteins)

HECW2 Protein Profile

Protein Summary

E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (By similarity).

Gene names and symbols associated with HECW2

  • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 (Hecw2)
  • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 (HECW2)
  • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 (hecw2)
  • A730039N16Rik protein
  • D030049F17Rik protein
  • Gm971 protein
  • HECW2 protein
  • mKIAA1301 protein
  • Nedl2 protein

Protein level used designations for HECW2

E3 ubiquitin-protein ligase HECW2 , HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 , E3 ubiquitin-protein ligase HECW2-like , e3 ubiquitin-protein ligase HECW2-like , HECT, C2 and WW domain-containing protein 2 , NEDD4-like E3 ubiquitin-protein ligase 2 , NEDD4-related E3 ubiquitin ligase NEDL2

GENE ID SPECIES
316395 Rattus norvegicus
424050 Gallus gallus
459844 Pan troglodytes
531691 Bos taurus
100055015 Equus caballus
100331355 Danio rerio
100411186 Callithrix jacchus
100444189 Pongo abelii
100469664 Ailuropoda melanoleuca
100560989 Anolis carolinensis
100602550 Nomascus leucogenys
57520 Homo sapiens
329152 Mus musculus
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