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The protein encoded by HECTD3 transfers ubiquitin from an E2 ubiquitin-conjugating enzyme to targeted substrates, leading to the degradation of those substrates. Additionally we are shipping HECT Domain Containing 3 Proteins (4) and many more products for this protein.
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Syntaxin 8 (show STX8 Antibodies) and HECTd3 have similar subcellular localization.
Overexpression of MALT1 (show MALT1 Antibodies) partially rescues HECTD3 depletion-induced apoptosis.
All these findings suggest that HECTD3 may facilitate cell cycle progression via regulating ubiquitination and degradation of Tara (show TRIOBP Antibodies).
The protein encoded by this gene transfers ubiquitin from an E2 ubiquitin-conjugating enzyme to targeted substrates, leading to the degradation of those substrates. The encoded protein has been shown to transfer ubiquitin to TRIOBP to facilitate cell cycle progression, and to STX8.
HECT domain containing 3
, E3 ubiquitin-protein ligase HECTD3
, HECT domain-containing protein 3
, probable E3 ubiquitin-protein ligase HECTD3