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anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) Antibodies

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Additionally we are shipping HACE1 Kits (7) and HACE1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HACE1 57531 Q8IYU2
HACE1 209462 Q3U0D9
HACE1 361866 D3ZBM7
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Top anti-HACE1 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-HACE1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Hela cell lysate Host: Rabbit  Target Name: HACE1  Sample Tissue: Hela Whole cell  Lane A:  Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 5 µg/mL Lysate Quantity: 41 µg/lane/LaneGel Concentration:.12 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon labeled with Anti HACE1 Polyclonal Antibody, Unconjugated (ABIN761141) followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB HACE1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$510.36
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Biotin IF, IHC (p), ELISA, WB   100 μg Log in to see 8 to 10 Days
$449.17
Details
Human Mouse FITC IF, IHC (p), ELISA, WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 8 to 10 Days
$478.50
Details

HACE1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-HACE1 Antibodies

  1. Chicken Polyclonal HACE1 Primary Antibody for WB - ABIN2774769 : Zhang, Anglesio, OSullivan, Zhang, Yang, Sarao, Mai, Cronin, Hara, Melnyk, Li, Wada, Liu, Farrar, Arceci, Sorensen, Penninger: The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers. in Nature medicine 2007 (PubMed)

More Antibodies against HACE1 Interaction Partners

Human HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) interaction partners

  1. HACE1 as a specific E3 ligase that polyubiquitinates YB-1 through non-canonical K27 linked ubiquitin chains.

  2. Biallelic loss-of-function mutations in HACE1 are associated with an autosomal recessive neurodevelopmental syndrome.

  3. supports a critical role for HACE1 in breast cancer progression and identifies patients that may benefit from Rac (show AKT1 Antibodies)-targeted therapies

  4. contrary to previous report, overexpression of HACE1 by transduction of recombinant protein did not affect proliferation or survival of NKTCL cell lines. We therefore conclude that HACE1 is not directly involved in NKTCL pathophysiology

  5. HACE1-OPTN (show OPTN Antibodies) axis synergistically suppresses growth and tumorigenicity of lung cancer cells.

  6. Ubiquitylation and activation of RAB11a (show RAB11A Antibodies) is promoted by a beta2 adrenergic receptor (show ADRB2 Antibodies)-HACE1 complex.

  7. HACE1 reduces oxidative stress and mutant Huntingtin (show HTT Antibodies) toxicity by promoting the NRF2 (show GABPA Antibodies) response.

  8. All stages of HCCs (show HCCS Antibodies) presented HACE1 methylation, indicating that the HACE1 gene has been methylated from the early stages of HCCs (show HCCS Antibodies).

  9. HACE1 is tumor suppressor gene located within the 6q21 region, and loss of function of multiple tumor suppressor genes within 6q21 may be a critical determinant of NK cell lymphomagenesis.

  10. HACE1 is an antagonist of cell migration through its ability to degrade active Rac1.

Mouse (Murine) HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) interaction partners

  1. Increased reactive oxygen species (ROS (show ROS1 Antibodies)) production due to Hace1 loss leads to glutamine (show GFPT1 Antibodies) addiction as a mechanism to cope with increased ROS (show ROS1 Antibodies)-induced oxidative stress.

  2. Data indicate that HECT E3 ubiquitin ligase (show MUL1 Antibodies) HACE1 deficiency accelerates pressure overload-induced heart failure.

  3. HACE1-OPTN (show OPTN Antibodies) axis synergistically suppresses growth and tumorigenicity of lung cancer cells.

  4. Hace1 controls ROS (show ROS1 Antibodies) generation of vertebrate Rac1-dependent NADPH oxidase (show NOX1 Antibodies) complexes.

HACE1 Antigen Profile

Protein Summary

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB (By similarity).

Gene names and symbols associated with HACE1

  • HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (HACE1) antibody
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (HACE1) antibody
  • HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (hace1) antibody
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (LOC100342048) antibody
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (hace1) antibody
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (Hace1) antibody
  • 1700042J16Rik antibody
  • A730034A22Rik antibody
  • BC025474 antibody
  • HACE1 antibody

Protein level used designations for HACE1

HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 , E3 ubiquitin-protein ligase HACE1 , HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1 , E3 ubiquitin-protein ligase HACE1-like , e3 ubiquitin-protein ligase HACE1-like

GENE ID SPECIES
100071887 Equus caballus
462900 Pan troglodytes
734146 Xenopus (Silurana) tropicalis
100342048 Oryctolagus cuniculus
100399774 Callithrix jacchus
100438368 Pongo abelii
100475389 Ailuropoda melanoleuca
100548893 Meleagris gallopavo
100562508 Anolis carolinensis
100581995 Nomascus leucogenys
446912 Xenopus laevis
421788 Gallus gallus
57531 Homo sapiens
475010 Canis lupus familiaris
100156102 Sus scrofa
527565 Bos taurus
209462 Mus musculus
361866 Rattus norvegicus
Selected quality suppliers for anti-HACE1 (HACE1) Antibodies
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