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HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) ELISA Kits

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Additionally we are shipping HACE1 Antibodies (25) and HACE1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HACE1 57531 Q8IYU2
HACE1 209462 Q3U0D9
HACE1 361866 D3ZBM7
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Top HACE1 ELISA Kits at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 6.25 pg/ml 25-1600 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 0.78-50 ng/mL 96 Tests Log in to see 11 to 13 Days
$875.60
Details
Rat
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
Details
Chicken
96 Tests Log in to see 11 to 13 Days
$1,095.60
Details

More ELISA Kits for HACE1 Interaction Partners

Human HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) interaction partners

  1. HACE1 as a specific E3 ligase that polyubiquitinates YB-1 through non-canonical K27 linked ubiquitin chains.

  2. Biallelic loss-of-function mutations in HACE1 are associated with an autosomal recessive neurodevelopmental syndrome.

  3. supports a critical role for HACE1 in breast cancer progression and identifies patients that may benefit from Rac (show AKT1 ELISA Kits)-targeted therapies

  4. contrary to previous report, overexpression of HACE1 by transduction of recombinant protein did not affect proliferation or survival of NKTCL cell lines. We therefore conclude that HACE1 is not directly involved in NKTCL pathophysiology

  5. HACE1-OPTN (show OPTN ELISA Kits) axis synergistically suppresses growth and tumorigenicity of lung cancer cells.

  6. Ubiquitylation and activation of RAB11a (show RAB11A ELISA Kits) is promoted by a beta2 adrenergic receptor (show ADRB2 ELISA Kits)-HACE1 complex.

  7. HACE1 reduces oxidative stress and mutant Huntingtin (show HTT ELISA Kits) toxicity by promoting the NRF2 (show GABPA ELISA Kits) response.

  8. All stages of HCCs (show HCCS ELISA Kits) presented HACE1 methylation, indicating that the HACE1 gene has been methylated from the early stages of HCCs (show HCCS ELISA Kits).

  9. HACE1 is tumor suppressor gene located within the 6q21 region, and loss of function of multiple tumor suppressor genes within 6q21 may be a critical determinant of NK cell lymphomagenesis.

  10. HACE1 is an antagonist of cell migration through its ability to degrade active Rac1.

Mouse (Murine) HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) interaction partners

  1. Increased reactive oxygen species (ROS (show ROS1 ELISA Kits)) production due to Hace1 loss leads to glutamine (show GFPT1 ELISA Kits) addiction as a mechanism to cope with increased ROS (show ROS1 ELISA Kits)-induced oxidative stress.

  2. Data indicate that HECT E3 ubiquitin ligase HACE1 deficiency accelerates pressure overload-induced heart failure.

  3. HACE1-OPTN (show OPTN ELISA Kits) axis synergistically suppresses growth and tumorigenicity of lung cancer cells.

  4. Hace1 controls ROS (show ROS1 ELISA Kits) generation of vertebrate Rac1-dependent NADPH oxidase (show NOX1 ELISA Kits) complexes.

HACE1 Antigen Profile

Antigen Summary

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB (By similarity).

Gene names and symbols associated with HACE1

  • HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (HACE1) antibody
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (HACE1) antibody
  • HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (hace1) antibody
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (LOC100342048) antibody
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (hace1) antibody
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (Hace1) antibody
  • 1700042J16Rik antibody
  • A730034A22Rik antibody
  • BC025474 antibody
  • HACE1 antibody

Protein level used designations for HACE1

HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 , E3 ubiquitin-protein ligase HACE1 , HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1 , E3 ubiquitin-protein ligase HACE1-like , e3 ubiquitin-protein ligase HACE1-like

GENE ID SPECIES
100071887 Equus caballus
462900 Pan troglodytes
734146 Xenopus (Silurana) tropicalis
100342048 Oryctolagus cuniculus
100399774 Callithrix jacchus
100438368 Pongo abelii
100475389 Ailuropoda melanoleuca
100548893 Meleagris gallopavo
100562508 Anolis carolinensis
100581995 Nomascus leucogenys
446912 Xenopus laevis
421788 Gallus gallus
57531 Homo sapiens
475010 Canis lupus familiaris
100156102 Sus scrofa
527565 Bos taurus
209462 Mus musculus
361866 Rattus norvegicus
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