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HIV-1 Rev Binding Protein Proteins (HRB)

The protein encoded by HRB is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. Additionally we are shipping HIV-1 Rev Binding Protein Antibodies (55) and HIV-1 Rev Binding Protein Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat HRB HRB 689529  
HRB 3267 P52594
HRB 15463 Q8K2K6
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Top HIV-1 Rev Binding Protein Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

HRB Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for HIV-1 Rev Binding Protein (HRB) Interaction Partners

Human HIV-1 Rev Binding Protein (HRB) interaction partners

  1. HRB knock-down affected CD4 (show CD4 Proteins) downregulation induced by Nef but not by HIV-1 Vpu.

  2. Selenite caused CYLD (show CYLD Proteins) upregulation via LEF1 (show LEF1 Proteins) and cIAP downregulation, both of which contribute to the degradation of ubiquitin chains on RIP1 (show UQCRFS1 Proteins) and subsequent caspase-8 (show CASP8 Proteins) activation and colorectal tumor cell apoptosis.

  3. The top primary GWAS association of Airway hyperresponsiveness was in rs6731443 (P-value 2.5E-06) located within the AGFG1 genes.

  4. Association ofalpha-synuclein with Rab attachment receptor protein and soluble sensitive factor attachment receptors (SNAREs) highlights a key role for membrane transport defects in alpha-synuclein-mediated pathology.

  5. The authors show that cells lacking functional HRB have significantly reduced production of influenza virus progeny and that this defect results from impaired viral ribonucleoprotein (vRNP) delivery to the plasma membrane.

  6. hRIP is an essential cellular Rev cofactor, which acts at a previously unanticipated step in HIV-1 RNA export.

  7. Study demonstrates that the clathrin-mediated endocytosis of the SNARE VAMP7 is directly mediated by Hrb, a clathrin adaptor and ArfGAP.

  8. HRB is involved in clathrin-dependent endocytosis and recruits TI-VAMP (show VAMP7 Proteins) in this process

Mouse (Murine) HIV-1 Rev Binding Protein (HRB) interaction partners

  1. Lack of an acrosome in Hrb mutant spermatids does not prevent the development of the acroplaxome. In the Hrb mutant, myosin-Va (show MYO5A Proteins)-bound proacrosome vesicles tether to the acroplaxome, where they flatten and form a flat sac (show ADCY10 Proteins), designated pseudoacrosome.

  2. Study demonstrates that the clathrin-mediated endocytosis of the SNARE VAMP7 is directly mediated by Hrb, a clathrin adaptor and ArfGAP.

HIV-1 Rev Binding Protein (HRB) Protein Profile

Protein Summary

The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HRB

  • ArfGAP with FG repeats 1a (agfg1a)
  • ArfGAP with FG repeats 1 (AGFG1)
  • ArfGAP with FG repeats 1 (agfg1)
  • hiv-1 rev binding protein (AaeL_AAEL000708)
  • HIV-1 Rev binding protein (LOC100358680)
  • Agfg1-ps1, ArfGAP with FG repeats 1, pseudogene 1 (Agfg1-ps1)
  • ArfGAP with FG repeats 1 (Agfg1)
  • agfg1 protein
  • AU045498 protein
  • C85612 protein
  • C130049H11Rik protein
  • D730048C23Rik protein
  • Hrb protein
  • MGC83726 protein
  • MGC97591 protein
  • RAB protein
  • Rip protein
  • wu:fb14f05 protein
  • wu:fi19d11 protein

Protein level used designations for HRB

ArfGAP with FG repeats 1 , HIV-1 Rev binding protein , arf-GAP domain and FG repeats-containing protein 1 , nucleoporin-like protein RIP , hiv-1 rev binding protein , HIV-1 Rev-binding protein , Rab, Rev/Rex activation domain-binding protein , arf-GAP domain and FG repeat-containing protein 1 , hRIP, Rev interacting protein , rev-interacting protein , rev/Rex activation domain-binding protein , HIV-1 Rev-binding protein homolog

GENE ID SPECIES
327597 Danio rerio
424793 Gallus gallus
432032 Xenopus laevis
459990 Pan troglodytes
477396 Canis lupus familiaris
548956 Xenopus (Silurana) tropicalis
708910 Macaca mulatta
5565923 Aedes aegypti
100358680 Oryctolagus cuniculus
689529 Rattus norvegicus
3267 Homo sapiens
536149 Bos taurus
15463 Mus musculus
363266 Rattus norvegicus
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