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Oxidoreductase required for tumor suppression. Additionally we are shipping HIV-1 Tat Interactive Protein 2, 30kDa Proteins (14) and HIV-1 Tat Interactive Protein 2, 30kDa Kits (1) and many more products for this protein.
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Human Polyclonal HTATIP2 Primary Antibody for ELISA, WB - ABIN250207
Shtivelman: A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma. in Oncogene 1997
TIP30 expression is associated with a good prognosis in patients with tumors.
these data suggest that positive MCM2 (show MCM2 Antibodies) and negative TIP30 expression are closely correlated with the clinical, pathological and biological parameters, in addition to poor prognosis in patients with gallbladder cancer.
The results of the present study indicated that TIP30 may suppress oncogenesis and glioma progression, thereby improving the prognosis of patients with glioma.
combination of sorafenib and metformin inhibits proliferation and invasion in vitro, prolongs median survival, and reduces lung metastasis of HCC (show FAM126A Antibodies) in vivo. This effect is closely associated with the upregulation of TIP30
Increased HMGB1 (show HMGB1 Antibodies) and cleaved caspase-3 (show CASP3 Antibodies) stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer
Data iindicate TIP30 was a marker in predicting the prognosis of esophageal squamous cell carcinoma (ESCC).
the present study showed that loss of HTATIP2 expression was a frequent event in glioma and is associated with poor prognosis.
The results suggest a novel and critical role of TIP30 involved in hepatocellular carcinoma progression and aggressiveness.
Meta-analysis suggests that the rs2230199 C/G, rs1047286 C/T, rs11569536 G/A and rs2250656 A/G SNPs in the CC3 (show CCL14 Antibodies) gene may be associated with age-related macular degeneration risk.
The combination of HTATIP2 and MVD (show MVD Antibodies) predicts the converse survival of HCC (show FAM126A Antibodies) with or without sorafenib intervention.
Overexpression or knockdown of Htatip2 in hepatocytes affected fatty acid storage and oxidation, consistent with a novel role in mediating the differential effects of PKC isoforms on lipid metabolism.
Data suggest that TIP30 plays a negative regulatory role in oligodendroglial differentiation.
TIP30 is a key regulator for maintaining ER(+) and ER(-)luminal pools in the mammary luminal lineage, and loss of it promotes expansion of ER(+) luminal progenitors and mature cells and ER(+) mammary tumorigenesis.
TIP30 functions as a tumor suppressor to inhibit EGFR (show EGFR Antibodies) cytoplasmic and nuclear signaling and suppress adenocarcinogenesis in the lung.
TIP30 complex regulates EGFR (show EGFR Antibodies) endocytosis by facilitating the transport of V-ATPases from trans-Golgi network to early endosomes.
Results suggest that Tip30 is an intrinsic and negative regulator of MEC proliferation partly through the inhibition of Wisp2 and Igf-1 expression, and its absence in the mammary gland may predispose MECs to neoplastic transformation.
Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
HIV-1 Tat interactive protein 2, 30kDa
, HIV-1 tat interactive protein 2, homolog
, oxidoreductase HTATIP2
, tat-interacting protein 30 kDa
, 30 kDa HIV-1 TAT-interacting protein
, HIV-1 TAT-interactive protein 2
, Tat-interacting protein (30kD)
, short chain dehydrogenase/reductase family 44U, member 1
, HIV-1 tat interactive protein 2, 30 kDa homolog