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anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLAE) Antibodies

HLA-E belongs to the HLA class I heavy chain paralogues. Additionally we are shipping HLA Class I Histocompatibility Antigen, alpha Chain E Kits (13) and HLA Class I Histocompatibility Antigen, alpha Chain E Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HLAE 3133 P13747
HLAE    
HLAE    
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Top anti-HLA Class I Histocompatibility Antigen, alpha Chain E Antibodies at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS, IHC (p), IP Immunohistochemistry staining of human spleen (paraffin sections) with anti-HLA-E (clone MEM-E/06). Commercially tested by LifeSpan BioSciences. 0.1 mg Log in to see 4 to 5 Days
$277.20
Details
Human Mouse Un-conjugated FACS, IHC (p), IP Immunohistochemistry staining of human spleen (paraffin sections) with anti-HLA-E (clone MEM-E/07). Commercially tested by LifeSpan BioSciences. 0.1 mg Log in to see 4 to 5 Days
$277.20
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Biotin FACS, IHC (p), IP Immunohistochemistry staining of human spleen (paraffin sections) with anti-HLA-E (clone MEM-E/07). Commercially tested by LifeSpan BioSciences. 0.1 mg Log in to see 4 to 5 Days
$381.15
Details
Human Mouse Un-conjugated IHC (p), WB Human Spleen (formalin-fixed, paraffin-embedded) stained with HLA-E antibody ABIN364251 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated FACS, IHC (p), IP Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse APC ICFC 100 Tests Log in to see 10 to 12 Days
$266.33
Details
Human Mouse Un-conjugated IHC (p), WB   0.1 mg Log in to see 4 to 5 Days
$277.20
Details
Human Mouse PE FACS, IHC 100 Tests Log in to see 10 to 12 Days
$326.12
Details

HLAE Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Monkey , ,


Mouse (Murine)


Top referenced anti-HLA Class I Histocompatibility Antigen, alpha Chain E Antibodies

  1. Human Monoclonal HLAE Primary Antibody for FACS, IHC (p) - ABIN94356 : Soni, Karande: Glycodelin A suppresses the cytolytic activity of CD8+ T lymphocytes. in Molecular immunology 2010 (PubMed)
    Show all 6 references for ABIN94356

  2. Human Monoclonal HLAE Primary Antibody for ICFC - ABIN2658335 : Sullivan, Clements, Rossjohn, Brooks: The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity. in Tissue antigens 2008 (PubMed)
    Show all 6 references for ABIN2658335

  3. Human Monoclonal HLAE Primary Antibody for FACS, IHC - ABIN2663742 : Koller, Geraghty, Shimizu, DeMars, Orr: HLA-E. A novel HLA class I gene expressed in resting T lymphocytes. in Journal of immunology (Baltimore, Md. : 1950) 1988 (PubMed)
    Show all 6 references for ABIN2663742

  4. Human Monoclonal HLAE Primary Antibody for FACS, IHC (p) - ABIN94354 : Das, Long: Lytic granule polarization, rather than degranulation, is the preferred target of inhibitory receptors in NK cells. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 5 references for ABIN94354

  5. Human Monoclonal HLAE Primary Antibody for IHC (p), WB - ABIN94352 : Platonova, Cherfils-Vicini, Damotte, Crozet, Vieillard, Validire, André, Dieu-Nosjean, Alifano, Régnard, Fridman, Sautès-Fridman, Cremer: Profound coordinated alterations of intratumoral NK cell phenotype and function in lung carcinoma. in Cancer research 2011 (PubMed)
    Show all 4 references for ABIN94352

  6. Human Monoclonal HLAE Primary Antibody for FACS, IHC (p) - ABIN1302714 : Lo Monaco, Tremante, Cerboni, Melucci, Sibilio, Zingoni, Nicotra, Natali, Giacomini: Human leukocyte antigen E contributes to protect tumor cells from lysis by natural killer cells. in Neoplasia (New York, N.Y.) 2011 (PubMed)
    Show all 2 references for ABIN1302714

More Antibodies against HLA Class I Histocompatibility Antigen, alpha Chain E Interaction Partners

Human HLA Class I Histocompatibility Antigen, alpha Chain E (HLAE) interaction partners

  1. HLA-E regulates NKG2C (show KLRC2 Antibodies)+ natural killer cell function through presentation of a restricted peptide repertoire

  2. HLA-E is capable of presenting a highly conserved peptide from HIV-1 capsid (AISPRTLNA) that is not recognized by NKG2A (show KLRC1 Antibodies)/CD94 (show KLRD1 Antibodies).

  3. over-expression of HLA-E is associated with melanoma

  4. Peptide-induced HLA-E expression in human PBMCs is dependent on peptide sequence and the HLA-E genotype.

  5. this study suggests that minor histocompatibility antigens presented by HLA-E can represent an additional risk factor following lung transplantation.

  6. These results indicate that E*01:01 is a novel protective genetic factor in EBV-associated cHL and support a role for HLA-E recognition on the control of EBV infection and lymphomagenesis.

  7. HLA-E molecules traffic differently from the HLA-class I (show MICA Antibodies) molecules and can play a fundamental role in the protection against intracellular pathogens and susceptibility to several diseases.

  8. Functional differences and the immunological impact of HLA-E allelic variant Arg107Gly

  9. increased risk of recurrent miscarriage in mothers carrying HLA-E*01:01 allele; meta-analysis

  10. The results derived from this study imply that HLA-E polymorphisms may influence RA susceptibility and affect clinical outcome of anti-TNF (show TNF Antibodies) therapy in female RA patients.

HLA Class I Histocompatibility Antigen, alpha Chain E (HLAE) Antigen Profile

Protein Summary

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Gene names and symbols associated with HLAE

  • major histocompatibility complex, class I, E (HLA-E) antibody
  • EA1.2 antibody
  • EA2.1 antibody
  • HLA-6.2 antibody
  • MHC antibody
  • QA1 antibody

Protein level used designations for HLAE

HLA class I histocompatibility antigen, E alpha chain , HLA class I histocompatibility antigen, alpha chain E , MHC HLA-E alpha-1 , MHC HLA-E alpha-2.1 , MHC class I antigen E , lymphocyte antigen

GENE ID SPECIES
3133 Homo sapiens
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