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HLA Class II DO alpha (HLA-DOA) ELISA Kits

HLA-DOA belongs to the HLA class II alpha chain paralogues. Additionally we are shipping HLA-DOA Antibodies (29) and HLA-DOA Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human HLA-DOA HLA-DOA 3111 P06340
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More ELISA Kits for HLA-DOA Interaction Partners

Human HLA Class II DO alpha (HLA-DOA) interaction partners

  1. significant association was found between white wine liking and rs9276975:C>T polymorphism in the HLA-DOA gene.

  2. TAP2 (show TAP2 ELISA Kits), HLA-DOA, HLA-DOB (show HLA-DOB ELISA Kits), and tapasin (show TAPBP ELISA Kits) loci are novel candidate regions for susceptibility to HCV infection and viral clearance in the Chinese population

  3. HLA-DO regulates surface presentation of human leukocyte antigen class II-restricted antigens on B cell malignancies.

  4. HLA-DOA, HLA-DRA, and HLA-DQA1 associated with spontaneous autoimmunity

  5. HLA-DOA mutations were analyzed for association with autoimmune diseases and B-cell leukemias.

  6. In transgenic mice expressing human HLA-DOA & HLA-DOB from a DC-specific promoter, as DO increased, A(b)-CLIP increased & class II-peptides decreased. DO impaired H-2M function, causing Ag-specific downmodulation of class II Ag processing/presentation.

  7. four novel HLA-DOA alleles, DOA*010106, DOA*0102, DOA*0103, and DOA*0104N, were identified by sequence-based typing

  8. minor allele of the SNP rs9296068 is significantly associated with liver transplantation rejection and with enhanced B-lymphocyte (show AKAP17A ELISA Kits) participation in rejection, likely because of a dysfunctional HLA-DOA gene product.

  9. HLA-DOA polymorphisms are associated with Diabetes Mellitus, Type 1.

HLA-DOA Antigen Profile

Antigen Summary

HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

Gene names and symbols associated with HLA-DOA

  • major histocompatibility complex, class II, DO alpha (HLA-DOA) antibody
  • HLA-DNA antibody
  • HLA-DZA antibody
  • HLADZ antibody

Protein level used designations for HLA-DOA

HLA class II histocompatibility antigen, DO alpha chain , HLA-D0-alpha , MHC DN-alpha , MHC DZ alpha , MHC class II antigen DOA , lymphocyte antigen , major histocompatibility complex, class II, DN alpha

3111 Homo sapiens
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