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anti-HLA Class II DR beta 3 (HLA-DRB3) Antibodies

HLA-DRB3 belongs to the HLA class II beta chain paralogues. Additionally we are shipping HLA-DRB3 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HLA-DRB3 3125 P79483
HLA-DRB3    
HLA-DRB3    
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Top anti-HLA-DRB3 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HLA-DRB3 AntibodyTitration: 1.0 µg/mL  Positive Control: U937 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF ICC/IF Image Immunofluorescence analysis of methanol-fixed A549, using HLA-DRB3, antibody at 1:500 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated ICC   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of HepG2 cell lines, using HLA-DRB3 antibody. 100 μL Log in to see 9 Days
$302.50
Details
Human Mouse Un-conjugated FACS, WB Western Blot analysis of HLA-DRB3 expression in transfected 293T cell line by HLA-DRB3 MaxPab polyclonal antibody.Lane 1: HLA-DRB3 transfected lysate(29.26 KDa).Lane 2: Non-transfected lysate. HLA-DRB3 MaxPab polyclonal antibody. Western Blot analysis of HLA-DRB3 expression in human liver. 50 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of HLA-DRB3 expression in transfected 293T cell line by HLA-DRB3 MaxPab polyclonal antibody.Lane 1: HLA-DRB3 transfected lysate(29.37 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ICC, IF, WB   100 μL Log in to see 5 to 7 Days
$452.81
Details
Human Rabbit Un-conjugated IHC   100 μL Log in to see 8 to 10 Days
$581.17
Details

HLA-DRB3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
,

Mouse (Murine)


Rat (Rattus)


More Antibodies against HLA-DRB3 Interaction Partners

Human HLA Class II DR beta 3 (HLA-DRB3) interaction partners

  1. HLA-DRB3 affects type 1 diabetes risk and islet autoantibodies.

  2. this mouse model unravels a critical role for HLA-DR3 (show TNFRSF25 Antibodies) in generating an autoimmune response to SmD and lupus nephritis in the NZM2328 background.

  3. Haplotyping was done on 91 Southern Europe celiac patients. HLA-DR3 (show TNFRSF25 Antibodies)-DQ2 (show TOR1A Antibodies) without HLA-DR7-DQ2 (show TOR1A Antibodies) was present in 62.6%, HLA-DR7-DQ2 (show TOR1A Antibodies) without HLA-DR3 (show TNFRSF25 Antibodies)-DQ2 (show TOR1A Antibodies) was present in 16.5% and HLA-DR4 (show HLADRB4 Antibodies)-DQ8 without HLA-DQ2 (show TOR1A Antibodies) was present in 3.3%.

  4. Children with the HLA haplotype DR3 (show TNFRSF25 Antibodies)-DQ2 (show TOR1A Antibodies), especially homozygotes, were found to be at high risk for celiac disease autoimmunity and celiac disease early in childhood.

  5. The unusual DRB1 (show RBM45 Antibodies)*08:01 haplotype carrying DRB3*02:02 has been confirmed in a Dutch family.

  6. HLA-DRB3*02:02 on the DRB1 (show RBM45 Antibodies)*03:01 haplotype can contribute to type 1 diabetes risk.

  7. Prospective evaluation of matching for HLA-DRB3/4/5, -DQ, and -DP loci is warranted to reduce posttransplant risks in donor-recipient pairs matched for 7/8 HEL.

  8. Three sets of HLA-DR3 (show TNFRSF25 Antibodies)-positive haplotypes are designed that provide maximum risk of type 1 diabetes development in Indians and suggest a common Caucasian ancestor from which multiple haplotypes evolve independently.

  9. Heterozygosity of HLA-DRB3*01:01 and HLA-DRB4 (show HLADRB4 Antibodies)*01:01 as a potential predictor of fetal neonatal alloimmune thrombocytopenia.

  10. There was a strong sporadic inclusion body myositis association with the carriage of the DRB3*01:01 allele which was accounted for by its linkage disequilibrium with DRB1 (show RBM45 Antibodies)*03:01.

HLA-DRB3 Antigen Profile

Protein Summary

HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

Gene names and symbols associated with HLA-DRB3

  • major histocompatibility complex, class II, DR beta 3 (HLA-DRB3) antibody
  • HLA-DR3B antibody

Protein level used designations for HLA-DRB3

DR7 , HLA class II histocompatibility antigen, DR beta 3 chain , HLA class II histocompatibility antigen, DRB1-7 beta chain , MHC class II HLA-DR beta 3 chain , MHC class II antigen DR beta 3 chain , MHC class II antigen DRB3 , human leucocyte antigen DRB3

GENE ID SPECIES
3125 Homo sapiens
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