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The protein encoded by HOPX is a homeodomain protein that lacks certain conserved residues required for DNA binding. Additionally we are shipping HOP Homeobox Proteins (16) and HOP Homeobox Kits (3) and many more products for this protein.
Showing 10 out of 59 products:
Yeast Polyclonal HOPX Primary Antibody for WB - ABIN1686660
Honoré, Leffers, Madsen, Rasmussen, Vandekerckhove, Celis: Molecular cloning and expression of a transformation-sensitive human protein containing the TPR motif and sharing identity to the stress-inducible yeast protein STI1. in The Journal of biological chemistry 1992
Show all 4 references for ABIN1686660
Human Polyclonal HOPX Primary Antibody for EIA, FACS - ABIN952770
Yang, Sim, Kim, Park: Expression of the homeobox gene, HOPX, is modulated by cell differentiation in human keratinocytes and is involved in the expression of differentiation markers. in European journal of cell biology 2010
Show all 3 references for ABIN952770
Human Polyclonal HOPX Primary Antibody for FACS, WB - ABIN655402
Kovárová, Plachy, Kosla, Trejbalová, ?ermák, Hejnar: Downregulation of HOPX controls metastatic behavior in sarcoma cells and identifies genes associated with metastasis. in Molecular cancer research : MCR 2013
Human Polyclonal HOPX Primary Antibody for ICC, IF - ABIN4319670
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
The results suggest that HOPX may contribute to pathogenesis or manifestation of hypertrophic cardiomyopathy as a modifier gene.
Data show that binding of heat shock proteins Hsp70 (show HSP70 Antibodies) and Hsp90 (show HSP90 Antibodies) requires prior binding of Hop (show STIP1 Antibodies) protein to Hsp90 (show HSP90 Antibodies).
HOPX is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer.
GATA6 (show GATA6 Antibodies) and HOPX are critical nodes in a lineage-selective pathway that directly links effectors of airway epithelial specification to the inhibition of metastasis in the lung ADC (show ADC Antibodies) subtype.
HOPX-beta promoter methylation is a frequent and cancer-specific event in CRC (show CALR Antibodies) progression.
Knockdown of Hop (show STIP1 Antibodies) caused a decrease in the level of RhoC GTPase (show RHOC Antibodies), and significantly inhibited pseudopodia formation in Hs578T cells. Our data suggest that Hop (show STIP1 Antibodies) regulates directional cell migration by multiple unknown mechanisms.
HOPX/Hopx expression is reduced in multiple examples of human and murine cardiac hypertrophy and failure.
results identify distinct functions for the Hop (show STIP1 Antibodies) cochaperone, revealing an asymmetric mechanism for Hsp90 (show HSP90 Antibodies) regulation and client loading
HOP (show STIP1 Antibodies) is a novel modulator of late terminal differentiation in keratinocytes
Hopx regulates the expression of genes involved in regulation of apoptosis and survival and makes them refractory to Fas (show FAS Antibodies)-induced apoptosis.
Analysis of the hematopoietic stem/progenitor cell pool in Hopx-/- mice demonstrated significantly reduced cell frequencies and impaired engraftment in competitive repopulation assays, thus providing functional validation of this positional candidate gene
Type I alveolar cells expressing Hopx manifest plasticity to regenerate type II alveolar cells in the lung.
Peripherally Induced Tolerance Depends on Peripheral Regulatory T Cells That Require Hopx To Inhibit Intrinsic IL-2 (show IL2 Antibodies) Expression.
Hopx integrates Bmp and Wnt (show WNT2 Antibodies) signaling by physically interacting with activated Smads and repressing Wnt (show WNT2 Antibodies) genes.
Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells.
Hopx is required for the function of regulatory T cells induced by DCs and the promotion of DC-mediated T cell unresponsiveness in vivo.
Hdac2 (show HDAC2 Antibodies), Hopx, and Gata4 (show GATA4 Antibodies) coordinately regulate cardiac myocyte proliferation during embryonic development.
data show that Hop (show STIP1 Antibodies) can inhibit serum response factor-dependent transcriptional activation by recruiting histone deacetylase (HDAC (show HDAC1 Antibodies)) activity and can form a complex that includes HDAC2 (show HDAC2 Antibodies)
The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene.
, homeodomain-only protein
, Homeodomain-only protein
, lung cancer-associated Y protein
, not expressed in choriocarcinoma clone 1
, not expressed in choriocarcinoma protein 1
, odd homeobox 1 protein
, odd homeobox protein 1
, homeobox only domain
, homeobox-only protein
, homeodomain only protein
, odd homeobox 1
, global ischemia induced protein GIIG15B
, global ischemia-induced gene 15B protein
, global ischemia-induced protein 15B