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anti-Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) Antibodies

HEY1 encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Additionally we are shipping HEY1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HEY1 23462 Q9Y5J3
HEY1 15213  
HEY1 155437  
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Top anti-HEY1 Antibodies at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-HEY1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged HEY1 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, WB Detection limit for recombinant GST tagged HEY1 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of HEY1 expression in transfected 293T cell line by HEY1 monoclonal antibody (M02), clone 2F10.Lane 1: HEY1 transfected lysate(32.613 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged HEY1 is approximately 0.1ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, ELISA, WB Western Blot analysis of HEY1 expression in transfected 293T cell line by HEY1 monoclonal antibody (M01), clone 3B3.Lane 1: HEY1 transfected lysate(32.613 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged HEY1 is approximately 0.3ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

HEY1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
, ,
,
Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-HEY1 Antibodies

  1. Human Monoclonal HEY1 Primary Antibody for IF, WB - ABIN394054 : Buas, Kabak, Kadesch: The Notch effector Hey1 associates with myogenic target genes to repress myogenesis. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN394054

  2. Human Monoclonal HEY1 Primary Antibody for ELISA - ABIN394327 : Villaronga, Lavery, Bevan, Llanos, Belandia: HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions. in Oncogene 2010 (PubMed)
    Show all 5 references for ABIN394327

  3. Human Monoclonal HEY1 Primary Antibody for IF, ELISA - ABIN525186 : Tsuru, Setoguchi, Matsunoshita, Nagao-Kitamoto, Nagano, Yokouchi, Maeda, Ishidou, Yamamoto, Komiya: Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression. in British journal of cancer 2015 (PubMed)

  4. Dog (Canine) Polyclonal HEY1 Primary Antibody for WB - ABIN2776824 : Tang, Urs, Liaw: Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site. in Circulation research 2008 (PubMed)

  5. Human Monoclonal HEY1 Primary Antibody for ELISA, WB - ABIN525187 : Huang, Chu, Ye, Chen: Role of HERP and a HERP-related protein in HRD1-dependent protein degradation at the endoplasmic reticulum. in The Journal of biological chemistry 2014 (PubMed)

More Antibodies against HEY1 Interaction Partners

Human Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) interaction partners

  1. Expression of Hey1 induces translocation of FBXO45 (show FBXO45 Antibodies) into the nucleus.

  2. Overexpression of HEY1 and HEY2 (show HEY2 Antibodies) in esophageal squamous cell carcinoma (ESCC) is correlated to different indices of poor prognosis, and it is extrapolated that such overexpression is important in progression and development of ESCC tumorigenesis.

  3. bone morphogenic proteins within the serum of cell culture medium are potent inducers of endothelial Hey1 and Hey2 (show HEY2 Antibodies) gene expression within the first few hours after medium change

  4. PML (show PML Antibodies) degradation mechanism through Notch (show NOTCH1 Antibodies)/Hey1-induced repression of the PML (show PML Antibodies) deubiquitinase USP11 (show USP11 Antibodies) involved in brain tumour pathogenesis

  5. MMP9 (show MMP9 Antibodies) was a downstream effector of HEY1 that promotes the invasion of osteosarcoma cells. Knockdown of HEY1 decreased the expression of MMP9 (show MMP9 Antibodies).

  6. In prostate tumors, the overexpression of PTOV1 was associated with decreased expression of HEY1 and HES1, and this correlation was significant in metastatic lesions.

  7. a new HRD1 (show SYVN1 Antibodies)-associated membrane protein named HERP2, which is homologous to the previously identified HRD1 (show SYVN1 Antibodies) partner HERP1 (show HEY2 Antibodies). Despite sequence homology, HERP2 is constitutively expressed in cells, whereas HERP1 (show HEY2 Antibodies) is highly induced by ER stress.

  8. The identification of HEY1-NCOA2 (show NCOA2 Antibodies) can be used as an auxiliary diagnostic tool to differentiate meningeal hemangiopericytoma from mesenchymal chondrosarcoma.

  9. HEY1 was overexpressed in colorectal cancer, and correlated with perineural and vascular invasion and lymph node metastasis as well as poorer prognosis.

  10. Data show that the periodontal ligament-derived mesenchymal stem cells (hPDLSCs) on a Jagged-1 (show JAG1 Antibodies)-modified surface had increased expression of Notch (show NOTCH1 Antibodies) signaling target genes, Hes-1 and Hey-1, suggesting the involvement of Notch (show NOTCH1 Antibodies) signaling in hPDLSCs.

Mouse (Murine) Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) interaction partners

  1. Cyclic stretch enhanced the BMP-2induced osteoblastic differentiation through the inhibition of Hey1.

  2. Hes (show ATCAY Antibodies)/Hey signaling at the Atoh1 (show ATOH1 Antibodies) promoter has a role in selection of cell fate in the organ of Corti

  3. These in vitro and in vivo data support an anti-adipogenic role of COUP-TFII (show NR2F2 Antibodies) via downregulating the Notch (show NOTCH1 Antibodies) signaling target gene Hey1.

  4. Hey proteins mechanistically repress target genes via histone deacetylase (show HDAC1 Antibodies) recruitment and histone deacetylation.

  5. Hey1 and Hey2 (show HEY2 Antibodies) in endothelial cells play important roles in vascular development.

  6. findings indicate that Hey1 and Hey2 (show HEY2 Antibodies) control the spatial and temporal pattern of auditory HC differentiation.

  7. This study demonistrated that demonstrates that the lack of Hesr1 leads to an alteration in sensitivity to dopamine accompanied by enhanced prepulse inhibition.

  8. A muscle-specific (show EIF3K Antibodies) regulatory element of p57(kip2 (show CDKN1C Antibodies)) directly activated by muscle regulatory factors in myoblasts but repressed by the Notch (show NOTCH1 Antibodies) targets Hes1/Hey1 in progenitor cells, is identified.

  9. Notch (show NOTCH1 Antibodies)-RBPjk (show RBPJ Antibodies) signaling functions in part through Hey1-mediated inhibition of NFATc1 (show NFATC1 Antibodies) to suppress osteoblastogenesis, contributing to bone homeostasis in vivo

  10. These results indicate that Hesr1 and Hesr3 (show HEYL Antibodies) are essential for the generation of adult satellite cells and for the maintenance of skeletal muscle homeostasis.

Zebrafish Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) interaction partners

  1. Expression of seven hairy/E(spl (show SGPL1 Antibodies)) (her) genes is reported in three neurogenic areas of the adult zebrafish brain (telencephalon, hypothalamus, and midbrain) in relation to radial glia, proliferation, and neurogenesis.

  2. hey1 represents a target of Delta-Notch (show NOTCH1 Antibodies) signaling dynamically expressed during somite formation in zebrafish

Xenopus laevis Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) interaction partners

  1. Results suggest that the negative regulatory loops between BMP/Tbx2 (show TBX2 Antibodies) and Gremlin (show GREM1 Antibodies) or Hey1 are responsible for defining the territory of the pronephric nephron.

  2. HRT1 encodes a bhlh domain motif, a transcription repressor, which acts as an extended dimerization domain that contributes to the selection of partners.

  3. XHRT1 plays an important role in glomerular development and early proximodistal patterning. [Xenopus HRT1]

HEY1 Antigen Profile

Protein Summary

This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with HEY1

  • hairy/enhancer-of-split related with YRPW motif 1 (HEY1) antibody
  • hairy/enhancer-of-split related with YRPW motif 1 (Hey1) antibody
  • hairy/enhancer-of-split related with YRPW motif 1 (hey1) antibody
  • AI316788 antibody
  • AI414254 antibody
  • bc8 antibody
  • bHLHb31 antibody
  • chf2 antibody
  • herp2 antibody
  • hesr-1 antibody
  • hesr1 antibody
  • HRT-1 antibody
  • hrt1 antibody
  • id:ibd1292 antibody
  • oaf1 antibody
  • xbc8 antibody
  • zgc:110572 antibody

Protein level used designations for HEY1

HES-related repressor protein 1 , HES-related repressor protein 2 , basic helix-loop-helix protein OAF1 , cardiovascular helix-loop-helix factor 2 , class B basic helix-loop-helix protein 31 , hHRT1 , hairy and enhancer of split-related protein 1 , hairy-related transcription factor 1 , hairy/enhancer-of-split related with YRPW motif protein 1 , HESR-1 , bHLH protein Hesr-1/Hey1 , cardiovascular basic helix-loop-helix factor 2 , HRT-1 , Hairy/E(spl)-related with YRPW motif 1 , mHRT1 , IBD1292 , basic helix-loop-helix transcription factor , XHRT1 , XHey-1 , hesr-1 , protein xbc8 , xHRT-1

GENE ID SPECIES
23462 Homo sapiens
403420 Canis lupus familiaris
408005 Bos taurus
15213 Mus musculus
155437 Rattus norvegicus
58008 Danio rerio
399195 Xenopus laevis
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