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Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) ELISA Kits

HEY1 encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Additionally we are shipping HEY1 Antibodies (46) and HEY1 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human HEY1 HEY1 23462 Q9Y5J3
Anti-Mouse HEY1 HEY1 15213  
Anti-Rat HEY1 HEY1 155437  
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More ELISA Kits for HEY1 Interaction Partners

Human Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) interaction partners

  1. Expression of Hey1 induces translocation of FBXO45 (show FBXO45 ELISA Kits) into the nucleus.

  2. Overexpression of HEY1 and HEY2 (show HEY2 ELISA Kits) in esophageal squamous cell carcinoma (ESCC) is correlated to different indices of poor prognosis, and it is extrapolated that such overexpression is important in progression and development of ESCC tumorigenesis.

  3. bone morphogenic proteins within the serum of cell culture medium are potent inducers of endothelial Hey1 and Hey2 (show HEY2 ELISA Kits) gene expression within the first few hours after medium change

  4. PML (show PML ELISA Kits) degradation mechanism through Notch (show NOTCH1 ELISA Kits)/Hey1-induced repression of the PML (show PML ELISA Kits) deubiquitinase USP11 (show USP11 ELISA Kits) involved in brain tumour pathogenesis

  5. MMP9 (show MMP9 ELISA Kits) was a downstream effector of HEY1 that promotes the invasion of osteosarcoma cells. Knockdown of HEY1 decreased the expression of MMP9 (show MMP9 ELISA Kits).

  6. In prostate tumors, the overexpression of PTOV1 was associated with decreased expression of HEY1 and HES1, and this correlation was significant in metastatic lesions.

  7. a new HRD1 (show SYVN1 ELISA Kits)-associated membrane protein named HERP2, which is homologous to the previously identified HRD1 (show SYVN1 ELISA Kits) partner HERP1 (show HEY2 ELISA Kits). Despite sequence homology, HERP2 is constitutively expressed in cells, whereas HERP1 (show HEY2 ELISA Kits) is highly induced by ER stress.

  8. The identification of HEY1-NCOA2 (show NCOA2 ELISA Kits) can be used as an auxiliary diagnostic tool to differentiate meningeal hemangiopericytoma from mesenchymal chondrosarcoma.

  9. HEY1 was overexpressed in colorectal cancer, and correlated with perineural and vascular invasion and lymph node metastasis as well as poorer prognosis.

  10. Data show that the periodontal ligament-derived mesenchymal stem cells (hPDLSCs) on a Jagged-1 (show JAG1 ELISA Kits)-modified surface had increased expression of Notch (show NOTCH1 ELISA Kits) signaling target genes, Hes-1 and Hey-1, suggesting the involvement of Notch (show NOTCH1 ELISA Kits) signaling in hPDLSCs.

Mouse (Murine) Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) interaction partners

  1. Cyclic stretch enhanced the BMP-2induced osteoblastic differentiation through the inhibition of Hey1.

  2. Hes (show ATCAY ELISA Kits)/Hey signaling at the Atoh1 (show ATOH1 ELISA Kits) promoter has a role in selection of cell fate in the organ of Corti

  3. These in vitro and in vivo data support an anti-adipogenic role of COUP-TFII (show NR2F2 ELISA Kits) via downregulating the Notch (show NOTCH1 ELISA Kits) signaling target gene Hey1.

  4. Hey proteins mechanistically repress target genes via histone deacetylase (show HDAC1 ELISA Kits) recruitment and histone deacetylation.

  5. Hey1 and Hey2 (show HEY2 ELISA Kits) in endothelial cells play important roles in vascular development.

  6. findings indicate that Hey1 and Hey2 (show HEY2 ELISA Kits) control the spatial and temporal pattern of auditory HC differentiation.

  7. This study demonistrated that demonstrates that the lack of Hesr1 leads to an alteration in sensitivity to dopamine accompanied by enhanced prepulse inhibition.

  8. A muscle-specific (show EIF3K ELISA Kits) regulatory element of p57(kip2 (show CDKN1C ELISA Kits)) directly activated by muscle regulatory factors in myoblasts but repressed by the Notch (show NOTCH1 ELISA Kits) targets Hes1/Hey1 in progenitor cells, is identified.

  9. Notch (show NOTCH1 ELISA Kits)-RBPjk (show RBPJ ELISA Kits) signaling functions in part through Hey1-mediated inhibition of NFATc1 (show NFATC1 ELISA Kits) to suppress osteoblastogenesis, contributing to bone homeostasis in vivo

  10. These results indicate that Hesr1 and Hesr3 (show HEYL ELISA Kits) are essential for the generation of adult satellite cells and for the maintenance of skeletal muscle homeostasis.

Zebrafish Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) interaction partners

  1. Expression of seven hairy/E(spl (show SGPL1 ELISA Kits)) (her) genes is reported in three neurogenic areas of the adult zebrafish brain (telencephalon, hypothalamus, and midbrain) in relation to radial glia, proliferation, and neurogenesis.

  2. hey1 represents a target of Delta-Notch (show NOTCH1 ELISA Kits) signaling dynamically expressed during somite formation in zebrafish

Xenopus laevis Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1) interaction partners

  1. Results suggest that the negative regulatory loops between BMP/Tbx2 (show TBX2 ELISA Kits) and Gremlin (show GREM1 ELISA Kits) or Hey1 are responsible for defining the territory of the pronephric nephron.

  2. HRT1 encodes a bhlh domain motif, a transcription repressor, which acts as an extended dimerization domain that contributes to the selection of partners.

  3. XHRT1 plays an important role in glomerular development and early proximodistal patterning. [Xenopus HRT1]

HEY1 Antigen Profile

Antigen Summary

This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with HEY1

  • hairy/enhancer-of-split related with YRPW motif 1 (HEY1) antibody
  • hairy/enhancer-of-split related with YRPW motif 1 (Hey1) antibody
  • hairy/enhancer-of-split related with YRPW motif 1 (hey1) antibody
  • AI316788 antibody
  • AI414254 antibody
  • bc8 antibody
  • bHLHb31 antibody
  • chf2 antibody
  • herp2 antibody
  • hesr-1 antibody
  • hesr1 antibody
  • HRT-1 antibody
  • hrt1 antibody
  • id:ibd1292 antibody
  • oaf1 antibody
  • xbc8 antibody
  • zgc:110572 antibody

Protein level used designations for HEY1

HES-related repressor protein 1 , HES-related repressor protein 2 , basic helix-loop-helix protein OAF1 , cardiovascular helix-loop-helix factor 2 , class B basic helix-loop-helix protein 31 , hHRT1 , hairy and enhancer of split-related protein 1 , hairy-related transcription factor 1 , hairy/enhancer-of-split related with YRPW motif protein 1 , HESR-1 , bHLH protein Hesr-1/Hey1 , cardiovascular basic helix-loop-helix factor 2 , HRT-1 , Hairy/E(spl)-related with YRPW motif 1 , mHRT1 , IBD1292 , basic helix-loop-helix transcription factor , XHRT1 , XHey-1 , hesr-1 , protein xbc8 , xHRT-1

GENE ID SPECIES
23462 Homo sapiens
403420 Canis lupus familiaris
408005 Bos taurus
15213 Mus musculus
155437 Rattus norvegicus
58008 Danio rerio
399195 Xenopus laevis
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