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anti-Hairy and Enhancer of Split 5 (Drosophila) (HES5) Antibodies

HES5 encodes a member of a family of basic helix-loop-helix transcriptional repressors. Additionally we are shipping HES5 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HES5 388585 Q5TA89
HES5 15208 P70120
HES5 79225 Q03062
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Top anti-HES5 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HES5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: ACHN cell lysate WB Suggested Anti-HES5  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-HES5 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962705 concentration 41396 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated IHC (fro), IHC (p), ELISA, WB Mouse Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti Hes5 Polyclonal Antibody, Unconjugated (ABIN703811) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-Hes5 Polyclonal Antibody, Unconjugated (ABIN703811) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, WB The HES-5 Antibody is used in Western blot to detect HES-5 in mouse brain lysates. 0.1 mg Log in to see 2 to 6 Days
$403.70
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.34 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.34 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details

HES5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against HES5 Interaction Partners

Zebrafish Hairy and Enhancer of Split 5 (Drosophila) (HES5) interaction partners

  1. Over-expression of her12, her15 or her7 disrupts cyclic gene expression and somite border formation, and structure function analysis of Her7 indicates that DNA binding, but not Groucho-recruitment seems to be important in this process.

Human Hairy and Enhancer of Split 5 (Drosophila) (HES5) interaction partners

  1. that suppression of the HES5 leading to inhibition of proliferation may be one of the mechanisms against Hepatocellular carcinoma

  2. HES5 silencing is an early and recurrent change in prostate tumourigenesis

  3. these data identify HES5 as a key mediator of the Wnt-3a (show WNT3A Antibodies) proneurogenic effect occurring independently of the classical Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling cascade thus further deciphering crosstalk mechanisms of Wnt (show WNT2 Antibodies) and Notch (show NOTCH1 Antibodies) signaling pathways regulating cell fate

  4. the downstream Notch (show NOTCH1 Antibodies) signalling effector HES5 directly represses transcription of the E3 ligase Fbw7beta.

  5. Notch3 (show NOTCH3 Antibodies) and Hes5 are hypermethylated in human B cell acute lymphoblastic leukemia (ALL).

  6. Hes5 overactivation is associated with cell differentiation, thereby resulting in uterine carcinogenesis.

  7. In this study, HES 5 transcription factor was detected in the lining epithelium of human periapical cysts with limited inflammation, showing Notch (show NOTCH1 Antibodies) pathway activation in those cells.

  8. The expression of HES5 in adenocarcinoma was significantly higher than those in adenoma and normal control

  9. For marking and purifying neural stem cells to ascertain whether differences exist, we generated transgenic mice using promoters from Hes (show RRBP1 Antibodies) genes (pHes1 or pHes5) to drive expression of destabilized enhanced green fluorescent protein.

  10. Notch protein binding to Hes5-GFP is extinguished fast and recovered slowly, whereas Hes1-GFP is inhibited late and recovered quickly

Mouse (Murine) Hairy and Enhancer of Split 5 (Drosophila) (HES5) interaction partners

  1. This study demonstrated that Hes1 and Hes5 modulate not only maintenance of progenitor cells but also pituicyte versus neuron fate specification during neurohypophysis development.

  2. delivery of siRNA to Hes1 and Hes5 using a transfection reagent or siRNA to Hes1 encapsulated within nanoparticles increased hair cell numbers in non-toxin treated organotypic cultures of cochleae and maculae

  3. The transcription and expression patterns of Notch (show NOTCH1 Antibodies) pathway components (Notch 1 (show NOTCH1 Antibodies)-3, Delta1 and 4, Jagged1 (show JAG1 Antibodies)) and effectors (Hes1, Hes2 (show HES2 Antibodies), Hes5 and Nrarp (show NRARP Antibodies)) were evaluated in the mouse testis

  4. Hes1 and Hes5 regulate vascular remodeling and arterial fate specification of endothelial cells in the development of the brain; they are critical transducers of Notch (show NOTCH1 Antibodies) signals in brain vascular development.

  5. the downstream Notch (show NOTCH1 Antibodies) signalling effector HES5 directly represses transcription of the E3 ligase Fbw7beta.

  6. Data demonstrate that Hes5 levels in the utricle decreased after the application of siRNA and that the number of hair cells in these utricles was significantly larger than following control treatment.

  7. Epigenetic silencing of Hes5 leads to neuronal differentiation despite active Notch (show NOTCH1 Antibodies) signaling.

  8. Simultaneous overexpression of Hes5 and Sox21 (show SOX21 Antibodies) reveals Hes5 as a downstream effector of Sox21 (show SOX21 Antibodies) in adult hippocampus neurogenesis.

  9. This study suggested that Hes5 expression is serially activated first by Gcms and later by the canonical Notch (show NOTCH1 Antibodies) pathway

  10. Hes1, Hes5 and Hey1 (show HEY1 Antibodies) cooperatively inhibit hair cell formation, and one allele of Hes1, Hes5 or Hey1 (show HEY1 Antibodies) is sufficient for supporting cell (show PTPRJ Antibodies) production probably by lateral inhibition in the sensory epithelium.

HES5 Antigen Profile

Protein Summary

This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.

Gene names and symbols associated with HES5

  • hairy and enhancer of split-related 15.1 (her15.1) antibody
  • hairy and enhancer of split 5 (Drosophila) (HES5) antibody
  • hairy and enhancer of split 5 (Drosophila) (hes5) antibody
  • hairy and enhancer of split 5 (LOC100221262) antibody
  • hairy and enhancer of split 5 (LOC100226434) antibody
  • hairy and enhancer of split 5 (Drosophila) (Hes5) antibody
  • bHLHb38 antibody
  • fk51a02 antibody
  • her15 antibody
  • hes5 antibody
  • wu:fk51a02 antibody
  • zgc:136520 antibody

Protein level used designations for HES5

hairy and enhancer of split 5 , her15a , transcription factor HES-5 , Transcription factor HES-5 , class B basic helix-loop-helix protein 38

GENE ID SPECIES
359836 Danio rerio
419392 Gallus gallus
787633 Bos taurus
100195635 Salmo salar
100221262 Taeniopygia guttata
100226434 Taeniopygia guttata
388585 Homo sapiens
15208 Mus musculus
79225 Rattus norvegicus
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