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Hairy/enhancer-of-Split Related with YRPW Motif-Like Proteins (HEYL)

HEYL encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. Additionally we are shipping HEYL Antibodies (52) and HEYL Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HEYL 26508 Q9NQ87
HEYL 56198 Q9DBX7
Rat HEYL HEYL 313575  
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Top HEYL Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,827.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,883.83
Details

HEYL Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL) Interaction Partners

Human Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL) interaction partners

  1. repression of TGFbeta (show TGFB1 Proteins) signaling by Notch (show NOTCH1 Proteins) acting through HEYL may promote initiation of breast cancer

  2. Repression of androgen receptor (show AR Proteins) activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch (show NOTCH1 Proteins) effectors.

  3. In this study, we analyzed the effects of HESR1 (show HEY1 Proteins), -2, and -3 on DAT1 expression in human neuroblastoma (show ARHGEF16 Proteins) SH-SY5Y cells

Mouse (Murine) Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL) interaction partners

  1. repression of TGFbeta (show TGFB1 Proteins) signaling by Notch (show NOTCH1 Proteins) acting through HEYL may promote initiation of breast cancer

  2. These results indicate that Hesr1 (show HEY1 Proteins) and Hesr3 are essential for the generation of adult satellite cells and for the maintenance of skeletal muscle homeostasis.

  3. This study demonistrated that HeyL promotes neuronal differentiation of neural progenitor cells by activating proneural genes and by inhibiting the actions of other Hes (show ATCAY Proteins) and Hey family members.

HEYL Protein Profile

Protein Summary

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Gene names and symbols associated with HEYL

  • hairy/enhancer-of-split related with YRPW motif-like (HEYL)
  • hairy/enhancer-of-split related with YRPW motif-like (Heyl)
  • hairy/enhancer-of-split related with YRPW motif-like (heyl)
  • bHLHb33 protein
  • fk74e12 protein
  • hesr3 protein
  • Hey3 protein
  • Hrt3 protein
  • wu:fk74e12 protein

Protein level used designations for HEYL

HEY-like protein , HRT-3 , class B basic helix-loop-helix protein 33 , hHRT3 , hHeyL , hairy-related transcription factor 3 , hairy/enhancer-of-split related with YRPW motif 3 , hairy/enhancer-of-split related with YRPW motif-like protein , hairy and enhance of split related 3 , hairy and enhancer of split-related protein 3 , mHRT3 , basic helix-loop-helix transcription factor heyL

GENE ID SPECIES
26508 Homo sapiens
607804 Canis lupus familiaris
538609 Bos taurus
56198 Mus musculus
313575 Rattus norvegicus
335134 Danio rerio
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