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anti-Heart and Neural Crest Derivatives Expressed 1 (HAND1) Antibodies

The protein encoded by HAND1 belongs to the basic helix-loop-helix family of transcription factors. Additionally we are shipping HAND1 Proteins (11) and HAND1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HAND1 9421 O96004
HAND1 59112 P97832
HAND1 15110 Q64279
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Top anti-HAND1 Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB HAND1 Antibody (Center) (ABIN658328) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the HAND1 antibody detected the HAND1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using HAND1 (Ab-98) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of A549 cells, using HAND1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using HAND1 mouse mAb against truncated Trx-HAND1 recombinant protein (1) . 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 10 to 11 Days
$464.29
Details
Human Mouse Un-conjugated FACS, IF, WB Anti-HAND1 mouse monoclonal antibody (ABIN2454416) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HAND1 (RC200513). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HAND1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HAND1. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IF, ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Cow Rabbit Un-conjugated IC, IF, WB Western blot analysis of HAND1 expression in HeLa (A), H9C2 (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$522.50
Details

HAND1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) , , ,


Mouse (Murine) , , ,


Top referenced anti-HAND1 Antibodies

  1. Human Polyclonal HAND1 Primary Antibody for WB - ABIN658328 : Reamon-Buettner, Ciribilli, Traverso, Kuhls, Inga, Borlak: A functional genetic study identifies HAND1 mutations in septation defects of the human heart. in Human molecular genetics 2009 (PubMed)
    Show all 4 references for ABIN658328

  2. Human Monoclonal HAND1 Primary Antibody for WB - ABIN2869339 : Dai, Cserjesi: The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN2869339

  3. Human Monoclonal HAND1 Primary Antibody for ELISA, WB - ABIN969184 : Lexer, Welch, Durphy, Rieseberg: Natural selection for salt tolerance quantitative trait loci (QTLs) in wild sunflower hybrids: implications for the origin of Helianthus paradoxus, a diploid hybrid species. in Molecular ecology 2003 (PubMed)
    Show all 2 references for ABIN969184

  4. Human Polyclonal HAND1 Primary Antibody for IHC, ELISA - ABIN1532673 : Knöfler, Meinhardt, Vasicek, Husslein, Egarter: Molecular cloning of the human Hand1 gene/cDNA and its tissue-restricted expression in cytotrophoblastic cells and heart. in Gene 1999 (PubMed)

More Antibodies against HAND1 Interaction Partners

Human Heart and Neural Crest Derivatives Expressed 1 (HAND1) interaction partners

  1. Combined expression of NKX2-5 (show NKX2-5 Antibodies), HAND1, and NOTCH1 (show NOTCH1 Antibodies) coordinately contribute to cardiac malformations in Hhypoplastic left heart syndrome.

  2. These data show that miR (show MLXIP Antibodies)-363 negatively regulates the expression of HAND1

  3. Nuclear translocation of Hand-1 acts as a molecular switch to regulate vascular radiosensitivity in medulloblastoma tumors.

  4. DNA methylation (show HELLS Antibodies) status of NKX2-5 (show NKX2-5 Antibodies), GATA4 (show GATA4 Antibodies) and HAND1 in patients with tetralogy of fallot

  5. Increased methylation levels of HAND1 is associated with highly active Helicobacter pylori-related gastritis.

  6. This is the first report of mutations in the HAND1 gene in Chinese patients with VSD and provides new insight into the etiology of VSD

  7. Hand1 is dispensable for normal tyrosine hydroxylase (show TH Antibodies) and dopamine beta-hydroxylase (show DBH Antibodies) expression in sympathetic neurons, even when Hand2 (show HAND2 Antibodies) gene dosage is concurrently reduced by half.

  8. Somatic mutations in NKX2-5 (show NKX2-5 Antibodies), GATA4 (show GATA4 Antibodies), and HAND1 are not a common cause of tetralogy of Fallot or hypoplastic left heart.

  9. Mutations or sequence variations in HAND1 or NKX2-5 (show NKX2-5 Antibodies) genes may play role in etiology or pathogenesis of atrial isomerism.

  10. Our study shows no evidence of somatic NKX2-5 (show NKX2-5 Antibodies), GATA4 (show GATA4 Antibodies) and HAND1 mutations playing a role in the pathogenesis of Tetralogy of Fallot . Findings suggest that the GATA4 (show GATA4 Antibodies) and HAND1 germline mutations are associated with non-syndromic congenital heart disease.

Xenopus laevis Heart and Neural Crest Derivatives Expressed 1 (HAND1) interaction partners

  1. increased vascular endothelial growth factor(170) levels disturb Hand-1 expression in the region required for normal heart morphogenesis

Mouse (Murine) Heart and Neural Crest Derivatives Expressed 1 (HAND1) interaction partners

  1. Hand1 is involved in proper osteogenesis of the bone collar via its control of Ihh (show IHH Antibodies). Hand1 overexpression in the osteochondral progenitors caused defective prenatal diaphysis ossification. Hand1 inhibited Runx2 (show RUNX2 Antibodies) transactivation of the Ihh (show IHH Antibodies) proximal promoter.

  2. Re-expression of HAND1 in colon cancer cells induces terminal differentiation.

  3. Hand1 phosphoregulation in the distal arch neural crest has a critical role in craniofacial morphogenesis

  4. Suggest that prenatal alcohol exposure causes the over-expression of DHAND (show HAND2 Antibodies) and EHAND by increasing H3K14ac in the fetal heart.

  5. Hand1 is part of a novel regulatory pathway linking cardiac oxygen levels with oxygen consumption.

  6. that Hand1 homodimer plays a dominant role during development and its expression dosage is critical for survival, whereas Hand1 heterodimers can be either dispensable or play a regulatory role to modulate the activity of Hand1 homodimer in vivo.

  7. Data suggest that stress-induced MAPK8/9 and PRKAA1/2 regulate transcription factors Eomes/HAND1 and ID2, respectively. Together this network mediates induction of CSH1 by stress.

  8. Hand1-mediated activation of Tbeta4 is essential for yolk sac (show ADCY10 Antibodies) vasculogenesis and embryonic survival, and administration of synthetic TB4 partially rescues yolk sac (show ADCY10 Antibodies) capillary plexus formation in Hand1-null embryos.

  9. Data define a critical threshold of Hand1 expression that is necessary for embryonic survival.

  10. Results show that Hand1 regulates development of lateral mesoderm derivatives and its loss in extraembryonic mesoderm is the primary cause of lethality in Hand1-null embryos.

HAND1 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Gene names and symbols associated with HAND1

  • heart and neural crest derivatives expressed 1 (HAND1) antibody
  • heart and neural crest derivatives expressed 1 (hand1) antibody
  • eHAND basic helix-loop-helix transcription factor (EHAND) antibody
  • heart and neural crest derivatives expressed 1 (Hand1) antibody
  • heart and neural crest derivatives expressed transcript 1 (Hand1) antibody
  • bHLHa27 antibody
  • eHAND antibody
  • Ehand1 antibody
  • hand-1 antibody
  • Hand1 antibody
  • hand1-A antibody
  • HXT antibody
  • Th1 antibody
  • Thing1 antibody

Protein level used designations for HAND1

heart- and neural crest derivatives-expressed protein 1 , heart and neural crest derivatives expressed 1 , basic helix-loop-helix transcription factor HAND1 , eHAND basic helix-loop-helix transcription factor , Heart- and neural crest derivatives-expressed protein 1 , class A basic helix-loop-helix protein 27 , extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1 , heart and neural crest derivatives expressed transcript 1 , heart and neural crest derivatives-expressed protein 1 , eHAND , helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast , thing-1

GENE ID SPECIES
489164 Canis lupus familiaris
541594 Sus scrofa
462209 Pan troglodytes
549497 Xenopus (Silurana) tropicalis
714450 Macaca mulatta
100009575 Oryctolagus cuniculus
9421 Homo sapiens
59112 Rattus norvegicus
517952 Bos taurus
395812 Gallus gallus
443353 Ovis aries
373663 Xenopus laevis
15110 Mus musculus
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