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Heart and Neural Crest Derivatives Expressed 1 (HAND1) ELISA Kits

The protein encoded by HAND1 belongs to the basic helix-loop-helix family of transcription factors. Additionally we are shipping Heart and Neural Crest Derivatives Expressed 1 Antibodies (83) and Heart and Neural Crest Derivatives Expressed 1 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HAND1 9421 O96004
HAND1 59112 P97832
HAND1 15110 Q64279
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Top Heart and Neural Crest Derivatives Expressed 1 ELISA Kits at antibodies-online.com

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Human
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$875.60
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$1,029.60
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More ELISA Kits for Heart and Neural Crest Derivatives Expressed 1 Interaction Partners

Human Heart and Neural Crest Derivatives Expressed 1 (HAND1) interaction partners

  1. Combined expression of NKX2-5 (show NKX2-5 ELISA Kits), HAND1, and NOTCH1 (show NOTCH1 ELISA Kits) coordinately contribute to cardiac malformations in Hhypoplastic left heart syndrome.

  2. These data show that miR (show MLXIP ELISA Kits)-363 negatively regulates the expression of HAND1

  3. Nuclear translocation of Hand-1 acts as a molecular switch to regulate vascular radiosensitivity in medulloblastoma tumors.

  4. DNA methylation (show HELLS ELISA Kits) status of NKX2-5 (show NKX2-5 ELISA Kits), GATA4 (show GATA4 ELISA Kits) and HAND1 in patients with tetralogy of fallot

  5. Increased methylation levels of HAND1 is associated with highly active Helicobacter pylori-related gastritis.

  6. This is the first report of mutations in the HAND1 gene in Chinese patients with VSD and provides new insight into the etiology of VSD

  7. Hand1 is dispensable for normal tyrosine hydroxylase (show TH ELISA Kits) and dopamine beta-hydroxylase (show DBH ELISA Kits) expression in sympathetic neurons, even when Hand2 (show HAND2 ELISA Kits) gene dosage is concurrently reduced by half.

  8. Somatic mutations in NKX2-5 (show NKX2-5 ELISA Kits), GATA4 (show GATA4 ELISA Kits), and HAND1 are not a common cause of tetralogy of Fallot or hypoplastic left heart.

  9. Mutations or sequence variations in HAND1 or NKX2-5 (show NKX2-5 ELISA Kits) genes may play role in etiology or pathogenesis of atrial isomerism.

  10. Our study shows no evidence of somatic NKX2-5 (show NKX2-5 ELISA Kits), GATA4 (show GATA4 ELISA Kits) and HAND1 mutations playing a role in the pathogenesis of Tetralogy of Fallot . Findings suggest that the GATA4 (show GATA4 ELISA Kits) and HAND1 germline mutations are associated with non-syndromic congenital heart disease.

Xenopus laevis Heart and Neural Crest Derivatives Expressed 1 (HAND1) interaction partners

  1. increased vascular endothelial growth factor(170) levels disturb Hand-1 expression in the region required for normal heart morphogenesis

Mouse (Murine) Heart and Neural Crest Derivatives Expressed 1 (HAND1) interaction partners

  1. Hand1 is involved in proper osteogenesis of the bone collar via its control of Ihh (show IHH ELISA Kits). Hand1 overexpression in the osteochondral progenitors caused defective prenatal diaphysis ossification. Hand1 inhibited Runx2 (show RUNX2 ELISA Kits) transactivation of the Ihh (show IHH ELISA Kits) proximal promoter.

  2. Re-expression of HAND1 in colon cancer cells induces terminal differentiation.

  3. Hand1 phosphoregulation in the distal arch neural crest has a critical role in craniofacial morphogenesis

  4. Suggest that prenatal alcohol exposure causes the over-expression of DHAND (show HAND2 ELISA Kits) and EHAND by increasing H3K14ac in the fetal heart.

  5. Hand1 is part of a novel regulatory pathway linking cardiac oxygen levels with oxygen consumption.

  6. that Hand1 homodimer plays a dominant role during development and its expression dosage is critical for survival, whereas Hand1 heterodimers can be either dispensable or play a regulatory role to modulate the activity of Hand1 homodimer in vivo.

  7. Data suggest that stress-induced MAPK8/9 and PRKAA1/2 regulate transcription factors Eomes/HAND1 and ID2, respectively. Together this network mediates induction of CSH1 by stress.

  8. Hand1-mediated activation of Tbeta4 is essential for yolk sac (show ADCY10 ELISA Kits) vasculogenesis and embryonic survival, and administration of synthetic TB4 partially rescues yolk sac (show ADCY10 ELISA Kits) capillary plexus formation in Hand1-null embryos.

  9. Data define a critical threshold of Hand1 expression that is necessary for embryonic survival.

  10. Results show that Hand1 regulates development of lateral mesoderm derivatives and its loss in extraembryonic mesoderm is the primary cause of lethality in Hand1-null embryos.

Heart and Neural Crest Derivatives Expressed 1 (HAND1) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Gene names and symbols associated with HAND1

  • heart and neural crest derivatives expressed 1 (HAND1) antibody
  • heart and neural crest derivatives expressed 1 (hand1) antibody
  • eHAND basic helix-loop-helix transcription factor (EHAND) antibody
  • heart and neural crest derivatives expressed 1 (Hand1) antibody
  • heart and neural crest derivatives expressed transcript 1 (Hand1) antibody
  • bHLHa27 antibody
  • eHAND antibody
  • Ehand1 antibody
  • hand-1 antibody
  • Hand1 antibody
  • hand1-A antibody
  • HXT antibody
  • Th1 antibody
  • Thing1 antibody

Protein level used designations for HAND1

heart- and neural crest derivatives-expressed protein 1 , heart and neural crest derivatives expressed 1 , basic helix-loop-helix transcription factor HAND1 , eHAND basic helix-loop-helix transcription factor , Heart- and neural crest derivatives-expressed protein 1 , class A basic helix-loop-helix protein 27 , extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1 , heart and neural crest derivatives expressed transcript 1 , heart and neural crest derivatives-expressed protein 1 , eHAND , helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast , thing-1

GENE ID SPECIES
489164 Canis lupus familiaris
541594 Sus scrofa
462209 Pan troglodytes
549497 Xenopus (Silurana) tropicalis
714450 Macaca mulatta
100009575 Oryctolagus cuniculus
9421 Homo sapiens
59112 Rattus norvegicus
517952 Bos taurus
395812 Gallus gallus
443353 Ovis aries
373663 Xenopus laevis
15110 Mus musculus
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