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anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) Antibodies

Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Additionally we are shipping Heat Shock 105kDa/110kDa Protein 1 Proteins (14) and Heat Shock 105kDa/110kDa Protein 1 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSPH1 288444 Q66HA8
HSPH1 10808 Q92598
HSPH1 15505 Q61699
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Top anti-Heat Shock 105kDa/110kDa Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 122 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-HSPH1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 293T cell lysate Host: Rabbit  Target Name: HSPH1  Sample Tissue: Human MCF7  Antibody Dilution: 1.0 µg/mL HSPH1 is strongly supported by BioGPS gene expression data to be expressed in MCF7 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IP, IHC, WB Western blot analysis of Hsp105 expression in HeLa cell lysate. 100 μg Log in to see 2 to 3 Days
$304.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of HSPH1 Antibody (Center) (ABIN650749) in K562 cell line lysates (35 µg/lane). HSPH1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with HSPH1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of HSPH1 Antibody (C-term) (ABIN389381) in A2058 and A375 cell line lysates (35 µg/lane). HSPH1 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Hamster Rabbit Un-conjugated IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from HeLa cells, using HSP105 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using HSP105 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB Western blot analysis: Cell lysates of HeLa(30ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human HSP105 ? (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 100 μL Log in to see 7 to 8 Days
$374.00
Details

HSPH1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) ,
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Human , ,
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Mouse (Murine)


Top referenced anti-Heat Shock 105kDa/110kDa Protein 1 Antibodies

  1. Human Polyclonal HSPH1 Primary Antibody for EIA, WB - ABIN358041 : Ishihara, Yasuda, Hatayama: Molecular cloning, expression and localization of human 105 kDa heat shock protein, hsp105. in Biochimica et biophysica acta 1999 (PubMed)
    Show all 3 references for ABIN358041

  2. Human Monoclonal HSPH1 Primary Antibody for EIA, WB - ABIN263997 : Wang, Kazim, Repasky, Subjeck: Characterization of heat shock protein 110 and glucose-regulated protein 170 as cancer vaccines and the effect of fever-range hyperthermia on vaccine activity. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 3 references for ABIN263997

  3. Human Monoclonal HSPH1 Primary Antibody for ELISA, WB - ABIN306454 : Yamagishi, Ishihara, Saito, Hatayama: Hsp105 family proteins suppress staurosporine-induced apoptosis by inhibiting the translocation of Bax to mitochondria in HeLa cells. in Experimental cell research 2006 (PubMed)
    Show all 2 references for ABIN306454

  4. Chicken Polyclonal HSPH1 Primary Antibody for WB - ABIN2784830 : Meares, Zmijewska, Jope: HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation. in Cellular signalling 2008 (PubMed)

  5. Human Polyclonal HSPH1 Primary Antibody for IP, IHC - ABIN223112 : Oliver, Read, Kessler, Mehmeti, Wells, Huynh, Lin, Wechsler-Reya: Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma. in Development (Cambridge, England) 2005 (PubMed)

More Antibodies against Heat Shock 105kDa/110kDa Protein 1 Interaction Partners

Xenopus laevis Heat Shock 105kDa/110kDa Protein 1 (HSPH1) interaction partners

  1. These studies demonstrate that Xenopus hsp110 gene expression is constitutive and stress inducible in cultured cells and developmentally- and tissue specifically-regulated during early embryogenesis[hsp110]

Human Heat Shock 105kDa/110kDa Protein 1 (HSPH1) interaction partners

  1. About 25% of patients with stages II-III colorectal tumors with microsatellite instability have an excellent response to chemotherapy, due to large, biallelic deletions in the T(17) intron repeat of HSP110 in tumor DNA.

  2. HSP105 depletion disrupts the integration of protein phosphatase 2A into the beta-catenin (show CTNNB1 Antibodies) degradation complex, favoring the hyperphosphorylation and degradation of beta-catenin (show CTNNB1 Antibodies).

  3. A receiver operating characteristic curve constructed with HSP105 and TIM gave a sensitivity of 54.3% and 95% (38/40) specificity in discriminating esophageal squamous cell carcinoma from matched controls.

  4. we measured the binding of human Hsp72 (HSPA1A (show HSPA1A Antibodies)) to BAG1 (show BAG1 Antibodies), BAG2 (show BAG2 Antibodies), BAG3 (show BAG3 Antibodies), and the unrelated NEF Hsp105. These studies revealed a clear hierarchy of affinities: BAG3 (show BAG3 Antibodies) > BAG1 (show BAG1 Antibodies) > Hsp105 >> BAG2 (show BAG2 Antibodies).

  5. HSPH1 and HSPH2 are bona fide chaperones on their own that collaborate with DNAJA1 (show DNAJA1 Antibodies) and DNAJB1 (show DNAJB1 Antibodies) to hydrolyze ATP and unfold polypeptides and HSPA1A (show HSPA1A Antibodies) and HSPH1 formed a powerful molecular machinery.

  6. High HSP105 expression is associated with Barrett's esophagus.

  7. It restricts aggregation of denaturated proteins,plays a role in protein folding in cytoplasms,and enhance expression of hsp70 (show HSP70 Antibodies) in cell nucleus.(review)

  8. The Hsp105-mediated multilevel regulation of DeltaF508 CFTR (show CFTR Antibodies) folding and quality control provides new opportunities to understand how chaperone machinery regulates the homeostasis and functional expression of misfolded proteins in the cell.

  9. A direct correlation between HSP105 expression and lymphoma aggressiveness was also apparent.

  10. Hsp105alpha and Hsp105beta suppressed the expanded polyQ tract-induced protein aggregation and apoptosis through the induction of Hsp70 (show HSP70 Antibodies).

Mouse (Murine) Heat Shock 105kDa/110kDa Protein 1 (HSPH1) interaction partners

  1. Hsp105 may play an important role in the refolding of denatured proteins and protection against stress-induced cell death in mammalian cells.

  2. Hsp110 over-expression increases the immunogenicity of the murine CT26 (show DDX53 Antibodies) colon tumor.

  3. Data suggest that Hsp105 has opposite effects on stress-induced apoptosis depending on the cell type; a pro-apoptotic effect in embryonal cells and an anti-apoptotic effect in neuronal cells.

  4. enhances activation of p38 (show CRK Antibodies), release of cytochrome c (show CYCS Antibodies) and caspase (show CASP3 Antibodies) activation; may play important roles in organogenesis, during which marked apoptosis occurs, by enhancing apoptosis during mouse embryogenesis

  5. Hsp105alpha is suggested to regulate the substrate binding cycle of Hsp70/Hsc70 by inhibiting the ATPase activity of Hsp70/Hsc70, thereby functioning as a negative regulator of the Hsp70/Hsc70 chaperone system.

  6. The constitutive overexpression of HSP105 in cancer cells is involved in malignant transformation by protecting tumor cells from apoptosis.

  7. it is suggested that Hsp105 suppresses the stress-induced apoptosis at its initial step, the translocation of Bax (show BAX Antibodies) to mitochondria

  8. HSP105 appears to chaperone the responses to endoplasmic reticulum (ER) stress through its interactions with GRP78 (show HSPA5 Antibodies) and GSK3 (show GSK3b Antibodies), and without HSP105 cell death following ER stress proceeds by a non-caspase-3 (show CASP3 Antibodies)-dependent process.

  9. hsp110/105 KO mice are resistant to ischemic injury and that the protective effects of hsp110/105 deficiency in cerebral ischemia may partly be mediated by an increase in the chaperone activity of Hsp70 (show HSP70 Antibodies).

Heat Shock 105kDa/110kDa Protein 1 (HSPH1) Antigen Profile

Protein Summary

Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).

Gene names and symbols associated with HSPH1

  • heat shock 105kDa/110kDa protein 1 (hsph1) antibody
  • heat shock 105kDa/110kDa protein 1 (hsph1-b) antibody
  • heat shock 105kDa/110kDa protein 1 (HSPH1) antibody
  • heat shock 105/110 protein 1 (Hsph1) antibody
  • heat shock 105kDa/110kDa protein 1 (Hsph1) antibody
  • heat shock 105kDa/110kDa protein 1 (hsph1-a) antibody
  • 105kDa antibody
  • AI790491 antibody
  • hsp-E7I antibody
  • HSP105 antibody
  • HSP105A antibody
  • HSP105B antibody
  • Hsp110 antibody
  • hsph1 antibody
  • hsph1a antibody
  • hsph1b antibody
  • NY-CO-25 antibody

Protein level used designations for HSPH1

heat shock 105kD , heat shock protein 105 , heat shock 105kDa/110kDa protein 1b , heat shock 105kDa/110kDa protein 1 , heat shock protein 105 kDa-like , heat shock 105kDa , heat shock 110 kDa protein , heat shock protein 105 kDa , antigen NY-CO-25 , heat shock 105kD alpha , heat shock 105kD beta , heat shock 105kDa protein 1 , 42 degrees C-HSP , HSP105 42 C-HSP , heat shock protein 110 , heat shock protein, 105 kDa , heat shock-related 100 kDa protein E7I , heat shock 105kDa/110kDa protein 1a

GENE ID SPECIES
394775 Xenopus (Silurana) tropicalis
446527 Xenopus laevis
452522 Pan troglodytes
477322 Canis lupus familiaris
721956 Macaca mulatta
100062150 Equus caballus
100352543 Oryctolagus cuniculus
100394735 Callithrix jacchus
100466800 Ailuropoda melanoleuca
100546590 Meleagris gallopavo
100599947 Nomascus leucogenys
288444 Rattus norvegicus
10808 Homo sapiens
15505 Mus musculus
444063 Xenopus laevis
418917 Gallus gallus
100048931 Sus scrofa
507165 Bos taurus
Selected quality suppliers for anti-Heat Shock 105kDa/110kDa Protein 1 (HSPH1) Antibodies
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