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anti-Heat Shock 70kDa Protein 1A (HSPA1A) Antibodies

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. Additionally we are shipping HSPA1A Kits (38) and HSPA1A Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSPA1A 24472 Q07439
HSPA1A 3303 P08107
HSPA1A 193740 Q61696
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Top anti-HSPA1A Antibodies at

Showing 10 out of 134 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Caenorhabditis elegans Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated FACS, IF, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSPA1A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HSPA1A. Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-HSPA1A mouse monoclonal antibody. (ABIN2453149, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated IF, WB HSPA1A antibody   western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HSPA1A  antibody detected the HSPA1A  protein (arrow). Confocal immunofluorescent analysis of HSPA1A Antibody  with Hela cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
Human Mouse Un-conjugated IP, WB Western blot detection of HSPA1A in Hela and HsHela cell lysates using HSPA1A antibody (1: 1000 diluted).  Predicted band size: 70 kDa.  Observed band size: 70 kDa 100 μL Log in to see 8 to 9 Days
Human Mouse Un-conjugated ICC, WB Western blot detection of Hsp70(N-terminus) antibody in Heat shcok Hela, Hela and HepG2 lysates using Hsp70(N-terminus) antibody (1: 1000 diluted).  Predicted band size: 70 kDa.  Observed band size: 70 kDa. Immunocytochemistry stain of Hela using HSPA1A antibody (1: 300). 100 μL Log in to see 8 to 9 Days
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), WB Anti-Hsp70 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti-Hsp70 antibody, ICC ICC: A549 Cell 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IHC (p), WB Anti- Hsp70 Picoband antibody, IHC(P) IHC(P): Rat Intestine Tissue 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated WB WB Suggested Anti-Hspa1a AntibodyTitration: 1.0 µg/mL  Positive Control: Mouse Heart 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE antibody diluted at 1:10000 IHC-P Image HSP70 1A antibody detects HSPA1A protein at cytosol on H1299 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H1299 xenograft. HSP70 1A antibody , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days

HSPA1A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) ,
Human , , , ,
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Mouse (Murine) ,

Top referenced anti-HSPA1A Antibodies

  1. Caenorhabditis elegans (C. elegans) Polyclonal HSPA1A Primary Antibody for WB - ABIN2777745 : Narjoz, Marisa, Imbeaud, Paris, Delacroix, Beaune, De Waziers: Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells. in Chemical research in toxicology 2009 (PubMed)

  2. Human Monoclonal HSPA1A Primary Antibody for FACS, IF - ABIN2453149 : Ramdzan, Polling, Chia, Ng, Ormsby, Croft, Purcell, Bogoyevitch, Ng, Gleeson, Hatters: Tracking protein aggregation and mislocalization in cells with flow cytometry. in Nature methods 2012 (PubMed)

More Antibodies against HSPA1A Interaction Partners

Xenopus laevis Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. hsp72 was more potent than hsc73 (show HSPA8 Antibodies) in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. The cardioprotective effect of 40-60 g/d of alcohol consumption could be due in part, to increased intracellular HSPA1A, a potent anti-inflammatory protein. Excessive intake of alcohol increases antibodies anti-Hsp60 (show HSPD1 Antibodies), stimulating proinflammatory cytokines. This fact may explain the mortality from cardiovascular disease in heavy drinkers.

  2. There is a direct correlation between plasma HSPA1A and PAI-1 (show SERPINE1 Antibodies) levels in patients with diabetes, which is lost when they develop albuminuria.

  3. The present study revealed that salivary extracellular HSP70 (show HSP70 Antibodies) significantly increased at 4 h after the 59 min of intense exercise in sedentary male subjects and correlated with resting salivary secretory immunoglobulin A (SIgA) levels at rest.

  4. HSP70-2 (show HSPA1B Antibodies) (+1267A/G) gene polymorphism was associated with Henoch-Schonlein purpura in children

  5. HSP72 blocks fibroblast activation and proliferation in renal fibrosis via targeting the STAT3 (show STAT3 Antibodies) pathway and may serve as a novel therapeutic agent for chronic kidney disease regardless of the etiology

  6. Studies suggest that heat shock protein 72/70 (Hsp70 (show HSP70 Antibodies) proteins) are beneficial to the patient in slowing the onset of neurodegenerative disorders.

  7. P53 (show TP53 Antibodies) could be used to distinguish early HCC (show FAM126A Antibodies) from advanced hepatocellular carcinoma, but HSP70 (show HSP70 Antibodies) cannot

  8. cytokines, not being influenced by HSP72 polymorphisms, cortisol, or illness severity. Gln may depress l/mHSP72 after LPS (show IRF6 Antibodies) exposure and enhance them after HS induction, but it may not affect early induced HSP72 mRNA.

  9. heat acclimation reduces physiological strain, and the transcription of HSP72, but not HSP90alpha (show HSP90AA2 Antibodies) mRNA in acute normobaric hypoxia.

  10. Hsp72 (HSPA1A) prevents h-IAPP (show IAPP Antibodies) aggregation and toxicity.

Cow (Bovine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. Inhibition of Hsp70 (show HSP70 Antibodies) by using the Hsp70 (show HSP70 Antibodies) inhibitor KNK437 or knock down Hsp70 (show HSP70 Antibodies) using siRNA exaggerated and overexpression of Hsp70 (show HSP70 Antibodies) prevented the second phase disruption of lung endothelial integrity.

  2. Prostaglandin E synthase (show PTGES Antibodies) interacts with inducible heat shock protein 70 after heat stress in bovine primary dermal fibroblast cells.

  3. Hsp70-1A is a biomarker of low beef tenderness across the cattle breeds. [HSP70-1a]

  4. More DNMT1 (show DNMT1 Antibodies) mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (show ASCL2 Antibodies) mRNA was present at highest levels in transgenic SCNT embryos.

  5. the promoter region of bovine hsp70.1 gene is polymorphic and may be useful in selection of dairy cows for relatively better thermotolerance and higher milk production.

  6. Heat shock increased both HSP70 and IFNT expression in blastocysts.

  7. This study showed that Hsp70 (show HSP70 Antibodies) concentration is a reliable indicator of chronic stress but is not a reliable indicator of a single stressor when animals are exposed to multiple chronic stressors.

  8. the presence of SNPs (C/- and G/T) in the 5'-UTR (show UTS2R Antibodies) region of inducible Hsp70.1 ameliorates HS response and tolerance to heat of bovine peripheral blood mononuclear cells

  9. that HSC70 (show HSPA8 Antibodies) preconditioning (1) attenuates the TNF-alpha (show TNF Antibodies) response to endotoxin in macrophages in vitro, (2) induces cardiac functional tolerance to endotoxin and (3) reduces NF-kappaB (show NFKB1 Antibodies) activity, and TNF-alpha (show TNF Antibodies) and ICAM-1 (show ICAM1 Antibodies) levels in heart tissue.

  10. A new SNP in the 3'-UTR (show UTS2R Antibodies) of the hsp 70-1 (show HSP70 Antibodies) gene in Bos taurus and Bos indicus

Zebrafish Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. Perturbation of the HSP70-HSP90 (show HSP90 Antibodies) heat-shock protein axis stimulates degradation of endothelial VEGFR2 (show KDR Antibodies).

  2. HSP70, the earliest induced gene in the zebrafish retina after optic nerve injury, is a crucial factor for retinal ganglion cell survival and optic nerve regeneration.

  3. HSP70 mRNA and protein were increased 2.2 fold at 0.5-24 hours after optic nerve injury then returned to control level.

  4. hsp70 is required for embryonic lens development.

  5. data suggest that HSF1 (show HSF1 Antibodies) is involved in regulating constitutive lens specific expression of hsp70 in the embryonic zebrafish.

  6. in rheumatoid arthritis Significantly higher Hsp70 (heat shock protein 70 (show HSP70 Antibodies)) expression was found on synovial cells than on skin fibroblasts; high co-expression of CD91 (show LRP1 Antibodies) and Hsp70 on RA synovial cells

  7. These results demonstrate that induction of Hsp70 in response to heat stress is dependent on ERK (show MAPK1 Antibodies) activation in Pac2 (show PSMG2 Antibodies) cells.

  8. Hsp70 levels above the median were associated with a higher rate of progression to the accelerated/blast phase and a tendency toward shorter survival

Mouse (Murine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. HSPA1A/B induction is a novel approach to delay thrombus formation with minimal bleeding risk in knockout mice.

  2. HspA1A-phosphoinositide binding is complex yet specific, is mediated by both electrostatic and hydrophobic interactions, is not related to the lipid-head charge, and depends on the physicochemical properties of the lipid.

  3. The protective mechanism of HAS2 (show HAS2 Antibodies) involves an increased expression of the heat-shock protein Hsp72, a chaperone with antiapoptotic activity

  4. HspA1A embeds in membranes when bound to liposomes composed of cardiolipin and sulfatide.The two domains of HspA1A differentially bind to lipids, such as cardiolipin and sulfatide.

  5. Knockdown lines were created for specific DSBs in regions of the chromosome that are coding for HSPA1A. Clonogenic cell survival was significantly lower in irradiated Hsp70 (show HSP70 Antibodies) KD cells with low mHsp70 expression, than in ctrl cells.

  6. genetic manipulation of Hsp72 does not lead to alterations in metabolic processes in cardiac tissue under resting conditions, but identifies mouse strain-specific differences in cardiac lipid accumulation and insulin (show INS Antibodies)-stimulated glucose clearance.

  7. Data indicate that heat shock protein 70 (Hsp70 (show HSP70 Antibodies)) is higher in nuclear protein 1 (Nupr1 (show NUPR1 Antibodies)+/-) haplodeficient mice, concomitant with improved insulin (show INS Antibodies) sensitivity.

  8. HuR (show ELAVL1 Antibodies) does not play a role in APA (show ENPEP Antibodies) of the Hsp70.3 mRNA, and these two regulatory events appear to be mutually exclusive regulators of Hsp70.3 expression

  9. Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin (show INS Antibodies) resistance.

  10. Activation of HSP-72 upregulates lung injury associated with Pseudomonas aeruginosa pneumonia.

Pig (Porcine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. overexpression of the HSP70.2 (show HSPA2 Antibodies) gene in multiple organs of transgenic mice improves survival during heatstroke by reducing hyperthermia, circulatory shock, and cerebral ischemia and damage

HSPA1A Antigen Profile

Protein Summary

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Gene names and symbols associated with HSPA1A

  • heat shock 70kDa protein 1A (HSPA1A) antibody
  • heat shock 70kDa protein 1A (hspa1a) antibody
  • heat shock 70kD protein 1A (Hspa1a) antibody
  • heat shock cognate 70-kd protein (hsp70) antibody
  • heat shock protein 1A (Hspa1a) antibody
  • heat shock protein 70.2 (HSP70.2) antibody
  • hsp68 antibody
  • HSP70 antibody
  • HSP70-1 antibody
  • HSP70-1A antibody
  • HSP70-2 antibody
  • Hsp70-3 antibody
  • hsp70-4 antibody
  • Hsp70.3 antibody
  • hsp70A1 antibody
  • HSP70I antibody
  • Hsp72 antibody
  • HSPA1 antibody
  • HSPA1A antibody
  • HSPA1B antibody
  • HSPA2 antibody

Protein level used designations for HSPA1A

heat shock 70kDa protein 1A , HSP70-1/HSP70-2 , HSP70.1/2 , HSP70.1/HSP70.2 , heat shock 70 kDa protein 1/2 , heat shock 70 kDa protein 1A/1B , heat shock protein 70-1 , dnaK-type molecular chaperone HSP70-1 , heat shock 70kD protein 1A , heat shock-induced protein , 70 kda heat shock protein-2 , HSP70.2 , chaperone , heat shock 70 kD protein 2 , heat shock 70 kDa protein 1B , heat shock 70 kDa protein 2 , heat shock 70kDa protein 1B , heat-shock 70-kilodalton protein 1B , HSP70.1 , heat shock 70 kD protein 1 , heat shock 70 kDa protein 1 , heat shock 70 kDa protein 1A , heat-shock 70-kilodalton protein 1A , etID309743.10 , stress protein HSP70 , 68 kDa heat shock protein , heat shock 70 kDa protein 3 , heat shock protein, 70 kDa 3 , inducible heat shock protein 70

100023597 Monodelphis domestica
100554002 Anolis carolinensis
100608888 Pan troglodytes
24472 Rattus norvegicus
100381020 Xenopus laevis
3303 Homo sapiens
100354037 Oryctolagus cuniculus
282254 Bos taurus
100913152 Ovis aries
281825 Bos taurus
30671 Danio rerio
193740 Mus musculus
396648 Sus scrofa
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