anti-Heat Shock 70kDa Protein 4 (HSPA4) Antibodies

heat shock protein; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons. Additionally we are shipping Heat Shock 70kDa Protein 4 Kits (21) and Heat Shock 70kDa Protein 4 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSPA4 3308 P34932
HSPA4 15525  
HSPA4 266759 O88600
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Top anti-Heat Shock 70kDa Protein 4 Antibodies at antibodies-online.com

Showing 10 out of 117 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-HSPA4 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: HSPA4 Sample Type: Human 721_B Antibody Dilution: 1.0ug/ml  HSPA4 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells WB Suggested Anti-HSPA4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Hsp110 on a rat cerebrum lysate. Lane 1: 1:2500, lane 2: 1:5000, lane 3: 1:10,000 dilution of the mouse anti-Hsp110 antibody. Immunofluorescence staining of A431 cells (Human epithelial carcinoma, ATCC CRL-1555). 50 μg Log in to see 6 to 8 Days
$154.07
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Cow Rabbit HRP IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSP110 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Positive epidermal, dermal and muscle staining. Western blot analysis of Human Cell line lysates showing detection of HSP110 protein using Rabbit Anti-HSP110 Polyclonal Antibody . Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Donkey Anti-Rabbit IgG: HRP for 1 hour at RT. 100 μg Log in to see 2 to 3 Days
$369.60
Details
Cow Rabbit FITC IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSP110 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Positive epidermal, dermal and muscle staining. Western blot analysis of Human Cell line lysates showing detection of HSP110 protein using Rabbit Anti-HSP110 Polyclonal Antibody . Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Donkey Anti-Rabbit IgG: HRP for 1 hour at RT. 100 μg Log in to see 2 to 3 Days
$374.00
Details
Cow Rabbit Alkaline Phosphatase (AP) IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSP110 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Positive epidermal, dermal and muscle staining. Western blot analysis of Human Cell line lysates showing detection of HSP110 protein using Rabbit Anti-HSP110 Polyclonal Antibody . Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Donkey Anti-Rabbit IgG: HRP for 1 hour at RT. 100 μg Log in to see 2 to 3 Days
$376.20
Details
Cow Rabbit Biotin IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSP110 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Positive epidermal, dermal and muscle staining. Western blot analysis of Human Cell line lysates showing detection of HSP110 protein using Rabbit Anti-HSP110 Polyclonal Antibody . Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Donkey Anti-Rabbit IgG: HRP for 1 hour at RT. 100 μg Log in to see 2 to 3 Days
$378.40
Details
Cow Rabbit PE IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSP110 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Positive epidermal, dermal and muscle staining. Western blot analysis of Human Cell line lysates showing detection of HSP110 protein using Rabbit Anti-HSP110 Polyclonal Antibody . Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Donkey Anti-Rabbit IgG: HRP for 1 hour at RT. 100 μg Log in to see 2 to 3 Days
$379.50
Details
Cow Rabbit Streptavidin IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSP110 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Positive epidermal, dermal and muscle staining. Western blot analysis of Human Cell line lysates showing detection of HSP110 protein using Rabbit Anti-HSP110 Polyclonal Antibody . Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Rabbit Anti-HSP110 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Donkey Anti-Rabbit IgG: HRP for 1 hour at RT. 100 μg Log in to see 2 to 3 Days
$380.60
Details

HSPA4 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Heat Shock 70kDa Protein 4 Antibodies

  1. Dog (Canine) Monoclonal HSPA4 Primary Antibody for IF, IP - ABIN968011 : Lee-Yoon, Easton, Murawski, Burd, Subjeck: Identification of a major subfamily of large hsp70-like proteins through the cloning of the mammalian 110-kDa heat shock protein. in The Journal of biological chemistry 1995 (PubMed)
    Show all 2 Pubmed References

  2. Dog (Canine) Monoclonal HSPA4 Primary Antibody for IF, IP - ABIN968012 : Moore, Scheinman, Bellgrau: The identification of a novel T cell activation state controlled by a diabetogenic gene. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal HSPA4 Primary Antibody for ICC, IF - ABIN4320580 : Morisaki, Yashiro, Kakehashi, Inagaki, Kinoshita, Fukuoka, Kasashima, Masuda, Sakurai, Kubo, Muguruma, Ohira, Wanibuchi, Hirakawa: Comparative proteomics analysis of gastric cancer stem cells. in PLoS ONE 2014 (PubMed)

  4. Cow (Bovine) Polyclonal HSPA4 Primary Antibody for IHC, WB - ABIN863194 : Dragovic, Broadley, Shomura, Bracher, Hartl: Molecular chaperones of the Hsp110 family act as nucleotide exchange factors of Hsp70s. in The EMBO journal 2006 (PubMed)
    Show all 4 Pubmed References

More Antibodies against Heat Shock 70kDa Protein 4 Interaction Partners

Human Heat Shock 70kDa Protein 4 (HSPA4) interaction partners

  1. Here the authors show that in budding yeast, Hsf1 (show HSF1 Antibodies) basally associates with the chaperone Hsp70 (show HSP70 Antibodies) and this association is transiently disrupted by heat shock, providing the first evidence that a chaperone repressor directly regulates Hsf1 (show HSF1 Antibodies) activity.

  2. Pharmacological or genetic activation of heat shock protein 70 (Hsp70 (show HSP70 Antibodies)) protects against loss of parkin (show PARK2 Antibodies) Function. Heat shock protein members may act as compensatory factors for parkin (show PARK2 Antibodies) loss of function and that the exploitation of these factors may be of potential therapeutic value.

  3. targeting the Hsp70 (show HSP70 Antibodies) induction in Hsp90 (show HSP90 Antibodies) inhibitor-treated cancer cells and tumor vasculature cells may beneficially enhance the radiosensitizing effect

  4. The interaction of Fas receptor (show FAS Antibodies) with FasL (show FASL Antibodies) leads to an activation of the Tag7 (show PGLYRP1 Antibodies)-Hsp70 (show HSP70 Antibodies) complex in the lymphocyte membrane fraction, and here FasL (show FASL Antibodies) acts as a receptor that induces intracellular signaling in lymphocytes.An interaction of the MicA (show MICA Antibodies) stress ligand with the NKG2D (show KLRK1 Antibodies) receptor is necessary for the release of this cytotoxic complex

  5. Triptolide downregulates Sp1 (show PSG1 Antibodies) and HSP70 (show HSP70 Antibodies) mRNA in gastric cancer cell lines.

  6. HSP70 (show HSP70 Antibodies)-TRIM32 (show TRIM32 Antibodies) complex is biochemically distinct from the previously characterized 14-3-3 (show YWHAQ Antibodies)-TRIM32 (show TRIM32 Antibodies) phospho-complex.

  7. There is overwhelming evidence that molecular chaperones such as Hsp27 (show HSPB1 Antibodies), Hsp70 (show HSP70 Antibodies) and Hsp90 (show HSP90 Antibodies) are expressed at elevated levels in a wide range of cancers by stabilizing the mutated neoplasm proteins. (Review)

  8. HSP70 (show HSP70 Antibodies) is required for the maintenance of a functional mitotic centrosome that supports the assembly of a bipolar mitotic spindle.

  9. we demonstrated that upregulation of heat shock protein 70 (HSP70 (show HSP70 Antibodies)) was involved in both the promoted migration and the inhibited apoptosis of HepG2 cells in response to TNFalpha (show TNF Antibodies). Collectively, these findings indicate that TNFalpha (show TNF Antibodies) alters protein expression such as HSP70 (show HSP70 Antibodies), which triggering specific molecular processes and signaling cascades that promote migration and inhibit apoptosis of HepG2 cells.

  10. The authors show here that both Escherichia coli ClpB (show CLPB Antibodies) and Saccharomyces cerevisiae Hsp104 cooperation with their cognate Hsp70 (show HSP70 Antibodies) is crucial for efficient protein disaggregation and, in contrast to earlier claims, cannot be circumvented by activating M-domain mutations.

Mouse (Murine) Heat Shock 70kDa Protein 4 (HSPA4) interaction partners

  1. Data show that heat shock protein 70 (HSP70 (show HSP70 Antibodies)) induction by geranylgeranylacetone (GGA) was effective against N-methyl-N-nitrosourea (MNU-induced photoreceptor cell loss.

  2. Upregulation of HSPA4 would control apoptosis of inflammatory cells and immune response in the gut (show GUSB Antibodies), which might develop treatment resistance in inflammatory bowel disease.

  3. regulates the expression of SDF-1 (show CXCL12 Antibodies) and Twist in fibroblasts, thereby controlling gastric ulcer healing

  4. Inhibition of Apg-2 by shRNA not only decreased cell proliferation, but also induced cell apoptosis in BCR/ABL (show ABL1 Antibodies) positive chronic myeloid leukemia (show BCL11A Antibodies) cells (BaF3-BCR/ABL (show ABL1 Antibodies), BaF3-BCR/ABL (show ABL1 Antibodies)(T315I)).

  5. PSMB8 (show PSMB8 Antibodies), ALDH1A1 (show ALDH1A1 Antibodies), and HSPA4 were identified to be located in ovarian tissues, to regulate 12 cellular pathways, and demonstrate age-dependent dynamic changes in expression profiling.

  6. HSPA4L (show HSPA4L Antibodies) and HSPA4 collaborate in embryonic lung maturation, which is necessary for adaptation to air breathing at birth.

  7. study demonstrates that lack of HSPA4 leads to cardiac hypertrophy and fibrosis; data reveal the distinct, non-redundant role of HSPA4 in the protein quality control that maintains the proper protein folding and homeostasis in cardiomyocytes

  8. Data suggest HSPA4 is required for spermatogenesis. All homozygous HSPA4-deficient mice are apparently healthy; HSPA4 is expressed as early as E13.5 in male gonad; increased number of HSPA4-deficient males are infertile, whereas females are fertile.

  9. Findings provide in vivo evidence that Hsp110 (show HSPH1 Antibodies) plays a critical function in tau phosphorylation state through maintenance of efficient PP2A (show PPP2R2B Antibodies) activity, confirming its role in pathogenesis of Alzheimer's disease and other tauopathies.

  10. Overexpression of Apg-2 in proB-BCR/ABL (show ABL1 Antibodies) cells increases cell proliferation and protects cells from oxidative damage.

Zebrafish Heat Shock 70kDa Protein 4 (HSPA4) interaction partners

  1. Expression of hspa4a and hspa4b are up-regulated in the inflamed gut (show GUSB Antibodies) in a manner similar to that previously observed in mammals.

Heat Shock 70kDa Protein 4 (HSPA4) Antigen Profile

Protein Summary

heat shock protein\; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons

Gene names and symbols associated with HSPA4

  • heat shock 70kDa protein 4 (HSPA4) antibody
  • heat shock 70kDa protein 4 (hspa4) antibody
  • heat shock protein 4 (Hspa4) antibody
  • heat shock protein 4b (hspa4b) antibody
  • 70kDa antibody
  • AI317151 antibody
  • APG-2 antibody
  • HS24/P52 antibody
  • Hsp70 antibody
  • Hsp70RY antibody
  • Hsp110 antibody
  • hspa4 antibody
  • hspa4-a antibody
  • HSPH2 antibody
  • irp94 antibody
  • mKIAA4025 antibody
  • osp94 antibody
  • pg-2 antibody
  • RY antibody
  • wu:fi30e11 antibody
  • zgc:55743 antibody
  • zgc:77413 antibody

Protein level used designations for HSPA4

heat shock 70 kDa protein 4 , heat shock 70-related protein APG-2 , heat shock 70kD protein 4 , heat shock protein, 110 kDa , hsp70 RY , heat shock protein Apg-2 , ischemia responsive 94 kDa protein , heat shock protein 4

GENE ID SPECIES
100171909 Pongo abelii
398863 Xenopus laevis
416339 Gallus gallus
3308 Homo sapiens
474680 Canis lupus familiaris
536558 Bos taurus
100524853 Sus scrofa
15525 Mus musculus
266759 Rattus norvegicus
334086 Danio rerio
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