Heat Shock 70kDa Protein 4 Proteins (HSPA4)

heat shock protein\; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons [RGD, Feb 2006].. Additionally we are shipping Heat Shock 70kDa Protein 4 Antibodies (117) and Heat Shock 70kDa Protein 4 Kits (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HSPA4 3308 P34932
HSPA4 15525  
Rat HSPA4 HSPA4 266759 O88600
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Heat Shock 70kDa Protein 4 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$669.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$866.25
Details

HSPA4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)

More Proteins for Heat Shock 70kDa Protein 4 (HSPA4) Interaction Partners

Human Heat Shock 70kDa Protein 4 (HSPA4) interaction partners

  1. verified the interaction of cellular chaperon HSP70 (show HSP70 Proteins) with Porcine reproductive and respiratory syndrome virus NSP12, and demonstrated that NSP12 could recruit HSP70 (show HSP70 Proteins) to maintain its own stability and benefit for the virus replication

  2. Modulatory action of extracellular HSP70 (show HSP70 Proteins) on A549 inflammatory response through RAGE (show AGER Proteins) was able to evoke important expression changes in monocyte, showing its relevance in influencing the interaction between cancer and immune system cell.

  3. Here the authors show that in budding yeast, Hsf1 (show HSF1 Proteins) basally associates with the chaperone Hsp70 (show HSP70 Proteins) and this association is transiently disrupted by heat shock, providing the first evidence that a chaperone repressor directly regulates Hsf1 (show HSF1 Proteins) activity.

  4. Pharmacological or genetic activation of heat shock protein 70 (Hsp70 (show HSP70 Proteins)) protects against loss of parkin (show PARK2 Proteins) Function. Heat shock protein members may act as compensatory factors for parkin (show PARK2 Proteins) loss of function and that the exploitation of these factors may be of potential therapeutic value.

  5. targeting the Hsp70 (show HSP70 Proteins) induction in Hsp90 (show HSP90 Proteins) inhibitor-treated cancer cells and tumor vasculature cells may beneficially enhance the radiosensitizing effect

  6. The interaction of Fas receptor (show FAS Proteins) with FasL (show FASL Proteins) leads to an activation of the Tag7 (show PGLYRP1 Proteins)-Hsp70 (show HSP70 Proteins) complex in the lymphocyte membrane fraction, and here FasL (show FASL Proteins) acts as a receptor that induces intracellular signaling in lymphocytes.An interaction of the MicA (show MICA Proteins) stress ligand with the NKG2D (show KLRK1 Proteins) receptor is necessary for the release of this cytotoxic complex

  7. Triptolide downregulates Sp1 (show PSG1 Proteins) and HSP70 (show HSP70 Proteins) mRNA in gastric cancer cell lines.

  8. HSP70 (show HSP70 Proteins)-TRIM32 (show TRIM32 Proteins) complex is biochemically distinct from the previously characterized 14-3-3 (show YWHAQ Proteins)-TRIM32 (show TRIM32 Proteins) phospho-complex.

  9. There is overwhelming evidence that molecular chaperones such as Hsp27 (show HSPB1 Proteins), Hsp70 (show HSP70 Proteins) and Hsp90 (show HSP90 Proteins) are expressed at elevated levels in a wide range of cancers by stabilizing the mutated neoplasm proteins. (Review)

  10. HSP70 (show HSP70 Proteins) is required for the maintenance of a functional mitotic centrosome that supports the assembly of a bipolar mitotic spindle.

Mouse (Murine) Heat Shock 70kDa Protein 4 (HSPA4) interaction partners

  1. Data show that heat shock protein 70 (HSP70 (show HSP70 Proteins)) induction by geranylgeranylacetone (GGA) was effective against N-methyl-N-nitrosourea (MNU-induced photoreceptor cell loss.

  2. Upregulation of HSPA4 would control apoptosis of inflammatory cells and immune response in the gut (show GUSB Proteins), which might develop treatment resistance in inflammatory bowel disease.

  3. regulates the expression of SDF-1 (show CXCL12 Proteins) and Twist in fibroblasts, thereby controlling gastric ulcer healing

  4. Inhibition of Apg-2 by shRNA not only decreased cell proliferation, but also induced cell apoptosis in BCR/ABL (show ABL1 Proteins) positive chronic myeloid leukemia (show BCL11A Proteins) cells (BaF3-BCR/ABL (show ABL1 Proteins), BaF3-BCR/ABL (show ABL1 Proteins)(T315I)).

  5. PSMB8 (show PSMB8 Proteins), ALDH1A1 (show ALDH1A1 Proteins), and HSPA4 were identified to be located in ovarian tissues, to regulate 12 cellular pathways, and demonstrate age-dependent dynamic changes in expression profiling.

  6. HSPA4L (show HSPA4L Proteins) and HSPA4 collaborate in embryonic lung maturation, which is necessary for adaptation to air breathing at birth.

  7. study demonstrates that lack of HSPA4 leads to cardiac hypertrophy and fibrosis; data reveal the distinct, non-redundant role of HSPA4 in the protein quality control that maintains the proper protein folding and homeostasis in cardiomyocytes

  8. Data suggest HSPA4 is required for spermatogenesis. All homozygous HSPA4-deficient mice are apparently healthy; HSPA4 is expressed as early as E13.5 in male gonad; increased number of HSPA4-deficient males are infertile, whereas females are fertile.

  9. Findings provide in vivo evidence that Hsp110 (show HSPH1 Proteins) plays a critical function in tau phosphorylation state through maintenance of efficient PP2A (show PPP2R2B Proteins) activity, confirming its role in pathogenesis of Alzheimer's disease and other tauopathies.

  10. Overexpression of Apg-2 in proB-BCR/ABL (show ABL1 Proteins) cells increases cell proliferation and protects cells from oxidative damage.

Zebrafish Heat Shock 70kDa Protein 4 (HSPA4) interaction partners

  1. Expression of hspa4a and hspa4b are up-regulated in the inflamed gut (show GUSB Proteins) in a manner similar to that previously observed in mammals.

Heat Shock 70kDa Protein 4 (HSPA4) Protein Profile

Protein Summary

heat shock protein\; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons

Gene names and symbols associated with HSPA4

  • heat shock protein family A (Hsp70) member 4 (HSPA4)
  • heat shock protein family A (Hsp70) member 4 S homeolog (hspa4.S)
  • heat shock protein 4 (Hspa4)
  • heat shock protein family A member 4 (Hspa4)
  • heat shock protein 4b (hspa4b)
  • 70kDa protein
  • AI317151 protein
  • APG-2 protein
  • HS24/P52 protein
  • Hsp70 protein
  • Hsp70RY protein
  • Hsp110 protein
  • hspa4 protein
  • hspa4-a protein
  • HSPH2 protein
  • irp94 protein
  • mKIAA4025 protein
  • osp94 protein
  • pg-2 protein
  • RY protein
  • wu:fi30e11 protein
  • zgc:55743 protein
  • zgc:77413 protein

Protein level used designations for HSPA4

heat shock 70 kDa protein 4 , heat shock 70-related protein APG-2 , heat shock 70kD protein 4 , heat shock protein, 110 kDa , hsp70 RY , heat shock protein Apg-2 , ischemia responsive 94 kDa protein , heat shock protein 4

GENE ID SPECIES
100171909 Pongo abelii
398863 Xenopus laevis
416339 Gallus gallus
3308 Homo sapiens
474680 Canis lupus familiaris
536558 Bos taurus
100524853 Sus scrofa
15525 Mus musculus
266759 Rattus norvegicus
334086 Danio rerio
Selected quality suppliers for Heat Shock 70kDa Protein 4 Proteins (HSPA4)
Did you look for something else?