anti-Heat Shock 70kDa Protein 8 (HSPA8) Antibodies

HSPA8 encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. Additionally we are shipping HSPA8 Proteins (27) and HSPA8 Kits (25) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSPA8 3312 P11142
Anti-Rat HSPA8 HSPA8 24468 P63018
HSPA8 15481 P63017
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Top anti-HSPA8 Antibodies at antibodies-online.com

Showing 10 out of 262 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Formalin-fixed and paraffin-embedded human brain tissue reacted with HSPA8 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of HSPA8 Antibody (N-term) (ABIN650754) in Hela cell line lysates (35 µg/lane). HSPA8 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185659 (2µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Mouse Un-conjugated AA, Bind, ELISA, ICC, IF, IHC, IP, PLA, WB Hsc70 (1F2 H5) human cell line mix copy. 50 μg Log in to see 2 to 3 Days
$220.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-HSPA8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 293T cell lysate Sample type: rat brain lysatePrimary Dilution: 1:1000Image Submitted By: Jennifer Morgan, PhD &, David BuschUniversity of Texas in Austin 100 μL Log in to see 2 to 3 Days
$289.00
Details
Goat Rabbit Un-conjugated IHC, WB WB Suggested Anti-HSPA8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: COLO205 cell lysate Sample Type: 1. Lamprey CNS (20ug)2. Rat Brain Lysate (20ug) Primary Dilution: 1:1000Secondary Antibody: Goat anti-Rabbit HRPSecondary Dilution: 1:4000Image Submitted by: Jennifer Morgan, PhD &, David BuschUniversity of Texas in Austin 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB NB100- (2?g/ml) staining of A431 cell lysate (35?g protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Western Blot: HSPA8/HSC71/Hsc70 Antibody [ABIN1885497] - Analysis of HSPA8 in A431 cell lysate using this antibody at 2 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB   400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), WB Anti-Hsc70 antibody, ICC ICC: HELA Cell Anti-Hsc70 antibody, IHC(F) IHC(F): Rat Intestine Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Hsc70 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details

HSPA8 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-HSPA8 Antibodies

  1. Human Monoclonal HSPA8 Primary Antibody for AA, Bind - ABIN361800 : Boorstein, Ziegelhoffer, Craig: Molecular evolution of the HSP70 multigene family. in Journal of molecular evolution 1994 (PubMed)
    Show all 10 references for 361800

  2. Human Polyclonal HSPA8 Primary Antibody for FACS, IF - ABIN1944844 : Tsukahara, Yoshioka, Muraki: Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70. in Molecular pharmacology 2000 (PubMed)
    Show all 2 references for 1944844

  3. Human Polyclonal HSPA8 Primary Antibody for ELISA, WB - ABIN188549 : Zhang, Fan, Becker, Graff, Lee, Francomano: Comparison of gene expression profile between human chondrons and chondrocytes: a cDNA microarray study. in Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2006 (PubMed)

  4. Human Polyclonal HSPA8 Primary Antibody for FACS, IF - ABIN650754 : Egerton, Moritz, Druker, Kelso, Simpson: Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes. in Biochemical and biophysical research communications 1996 (PubMed)

More Antibodies against HSPA8 Interaction Partners

Xenopus laevis Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. hsp72 (show HSPA1A Antibodies) was more potent than hsc73 in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  2. study demonstrates a critical role of Hsc70 in SV40 endoplasmic reticulum-to-cytosol penetration and reveal how SGTA (show SGTA Antibodies) controls Hsc70 to impact this process

  3. In fact, DnaJC5 (show DNAJC5 Antibodies) overexpression induced tau release in cells, neurons, and brain tissue, but only when activity of the chaperone Hsc70 was intact and when tau was able to associate with this chaperone.

  4. HSPA1A (show HSPA1A Antibodies) and HSPA8 have roles in parturition through stimulating immune inflammatory and estrogen response

  5. These results suggest that Bag1 (show BAG1 Antibodies) and Bag3 (show BAG3 Antibodies) control the stability of the Hsc70-client complex using at least two distinct protein-protein contacts, providing a previously under-appreciated layer of molecular regulation in the human Hsc70 system.

  6. While cerebrospinal fluid Nrf2 (show GABPA Antibodies) and HSPA8 do not appear to offer diagnostic biomarkers for Parkinson's disease (PD), the associations between Nrf2 (show GABPA Antibodies) levels and UPDRS scores in LRRK2 (show LRRK2 Antibodies) + PD patients merit further investigation

  7. HSPA8 maintains pluripotency of human pluripotent stem cells by binding to the master pluripotency regulator OCT4 (show POU5F1 Antibodies) and facilitating its DNA-binding activity.

  8. heat shock cognate 70 (HSC70) is an essential component of Aes (show AES Antibodies) foci in colorectal cancer cells.

  9. Cx43 (show GJA1 Antibodies)-Hsc70 interaction regulates cell cycle G1/S progression through a novel mechanism by which Cx43 (show GJA1 Antibodies)-Hsc70 interaction prevents the nuclear accumulation of p27 (show PAK2 Antibodies) through controlling the nuclear translocation of cyclin D1 (show CCND1 Antibodies)-CDK4 (show CDK4 Antibodies)-p27 (show PAK2 Antibodies) complex.

  10. serum HSC71 was identified as a novel serum biomarker of renal cell carcinoma (show MOK Antibodies), particularly useful in early diagnosis of clear-cell type.

Cow (Bovine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Single-particle fluorescence imaging tracks the dynamics of Hsc70 and its clathrin substrate in real time.

  2. The interaction of the molecular chaperone (show HSP90AA1 Antibodies) Hsc70 (HSPA8) with recombinant PrP (show PRNP Antibodies) was investigated.

  3. Structure of clathrin coat with bound Hsc70 and auxilin (show DNAJC6 Antibodies).

  4. specific association between HSP73 and gentamicin may reduce the chaperone activity of HSP73 in vitro and/or in vivo

  5. report role of HSC70 in the regulation of NMT

  6. studied the process of disassembly by using cryo-electron microscopy to identify the initial binding site of Hsc70 on clathrin-C58J baskets at pH 6, under which conditions disassembly does not proceed further. Hsc70 interactions involve two sites

  7. Coats assembled from recombinant clathrin are good substrates for ATP- and auxilin (show DNAJC6 Antibodies)-dependent, Hsc70-catalyzed uncoating.

  8. The structure of an Hsp110 (show HSPH1 Antibodies):Hsc70 nucleotide exchange complex, is reported.

  9. analysis of the formation of a stable complex between chaperonin-containing TCP-1 (show CCT6A Antibodies) (CCT (show TCP1 Antibodies)) and Hsc70

  10. Elevated expression of bovine heat shock cognate (hsc)70 protein increases diabetes and inflammation following islet beta cell damage in a transgenic mouse model.

Mouse (Murine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  2. Hsc70 interacts with FILIP to mediate its effects on non-muscle myosin IIb (show MYH10 Antibodies) and to regulate spine morphology

  3. HSPA1A (show HSPA1A Antibodies) and HSPA8 have roles in parturition through stimulating immune inflammatory and estrogen response

  4. intracellular Salmonella recruit the host proteins LAMP-2A and Hsc73, key components of the host protein turnover pathway known as chaperone-mediated autophagy involved in transport of cytosolic proteins to the lysosome for degradation.

  5. these data demonstrate a novel interaction between Hsc70 and TH that regulates the activity and localization of the enzyme to synaptic vesicles, suggesting an important role for Hsc70 in dopamine homeostasis.

  6. C terminus of the hsc-70 LID domain as the structural interface interacting with endosomal Phosphatidylserine

  7. the association of MNSFbeta (show FAU Antibodies) with HSPA8 may promote RANKL (show TNFSF11 Antibodies)-induced osteoclastogenesis.

  8. Hspa8 plays a vital role in genetic differences in responses to stress and ethanol and their interactions

  9. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

  10. mass spectrometry-based proteomic analysis identified heat shock cognate 70 (HSC70) as a novel binding protein of FSP27 (show CIDEC Antibodies)

HSPA8 Antigen Profile

Protein Summary

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HSPA8

  • heat shock 70kDa protein 8 (hspa8) antibody
  • heat shock 70kDa protein 8 (HSPA8) antibody
  • heat shock 70kDa protein 8 (Hspa8) antibody
  • heat shock protein 8 (Hspa8) antibody
  • heat shock protein 8 (hspa8) antibody
  • 2410008N15Rik antibody
  • HSC54 antibody
  • Hsc70 antibody
  • Hsc71 antibody
  • Hsc73 antibody
  • HSP71 antibody
  • Hsp73 antibody
  • Hspa10 antibody
  • LAP1 antibody
  • NIP71 antibody
  • wu:fb01g06 antibody
  • wu:fi48b06 antibody

Protein level used designations for HSPA8

LPS-associated protein 1 , N-myristoyltransferase inhibitor protein 71 , constitutive heat shock protein 70 , heat shock 70kd protein 10 , heat shock cognate 71 kDa protein , heat shock cognate protein 54 , lipopolysaccharide-associated protein 1 , Hsc70 ATPase , heat shock 70 kDa protein 8 , heat shock 70kd protein 10 (HSC71) , heat shock cognate 71 kD protein , Heat shock cognate protein 70 , heat shock 70kD protein 8 , heat shock protein 8 , heat shock protein A8 , heat shock cognate 70 , heat shock cognate 71 kDa protein-like protein , heat shock protein 70 cognate , heat shock cognate hsc73 , heat shock protein cognate 70 , heat shock 70kDa protein 8 , heat shock cognate 71-kd protein

GENE ID SPECIES
379319 Xenopus laevis
3312 Homo sapiens
281831 Bos taurus
24468 Rattus norvegicus
395853 Gallus gallus
479406 Canis lupus familiaris
100009679 Equus caballus
100172711 Pongo abelii
15481 Mus musculus
573376 Danio rerio
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