anti-Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) Antibodies

HSPA9 encodes a member of the heat shock protein 70 gene family. Additionally we are shipping HSPA9 Proteins (16) and HSPA9 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSPA9 3313 P38646
HSPA9 15526 P38647
HSPA9 291671  
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Top anti-HSPA9 Antibodies at antibodies-online.com

Showing 10 out of 171 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IP, IHC, WB Sample Type: 3. rat brain extract (80ug) Primary Antibody Dilution: 2ug/ml Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience Secondary Antibody Dilution: 1: 20,000 Image Submitted by: Yuzhi Chen University of Arkansas for Medical Science Sample Type: Mouse Brain Slices Red: primaryBlue: DAPIPrimary Dilution: 1:400 Secondary Antibody: Anti-Rabbit IgG Alexa 594Secondary Dilution: 1:400 Image Submitted By: Adahir Labrador-Garrido and Cintia Roodveldt University of Seville 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Grp75 / HSPA9 Antibody (Center) in K562 cell line lysates (35ug/lane). This demonstrates the HSPA9 antibody detected the HSPA9 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Caenorhabditis elegans Mouse Un-conjugated ICC, IF, IP, IHC, ELISA, WB Grp75(S52A 42) human cell lines mix. 100 μg Log in to see 2 to 3 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunofluorescence analysis of COS7 cells, using GRP75 Antibody. The picture on the right is treated with the synthesized peptide. Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- Grp75 Picoband antibody,IHC(P) IHC(P): Rat Kidney Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Caenorhabditis elegans Mouse HRP ICC, IF, IP, IHC, ELISA, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Grp75 Monoclonal Antibody, Clone S52A-42 . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Mouse Anti-Grp75 Monoclonal Antibody  at 1:100 for 12 hours at 4°C. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Mitochondria. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-Grp75 Antibody. (C) Composite. Western Blot analysis of Human HeLa cell lysates showing detection of Grp75 protein using Mouse Anti-Grp75 Monoclonal Antibody, Clone S52A-42 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Grp75 Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 2 to 3 Days
$418.00
Details
Caenorhabditis elegans Mouse FITC ICC, IF, IP, IHC, ELISA, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Grp75 Monoclonal Antibody, Clone S52A-42 . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Mouse Anti-Grp75 Monoclonal Antibody  at 1:100 for 12 hours at 4°C. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Mitochondria. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-Grp75 Antibody. (C) Composite. Western Blot analysis of Human HeLa cell lysates showing detection of Grp75 protein using Mouse Anti-Grp75 Monoclonal Antibody, Clone S52A-42 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Grp75 Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 2 to 3 Days
$422.40
Details
Caenorhabditis elegans Mouse Alkaline Phosphatase (AP) ICC, IF, IP, IHC, ELISA, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Grp75 Monoclonal Antibody, Clone S52A-42 . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Mouse Anti-Grp75 Monoclonal Antibody  at 1:100 for 12 hours at 4°C. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Mitochondria. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-Grp75 Antibody. (C) Composite. Western Blot analysis of Human HeLa cell lysates showing detection of Grp75 protein using Mouse Anti-Grp75 Monoclonal Antibody, Clone S52A-42 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Grp75 Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 2 to 3 Days
$424.60
Details
Caenorhabditis elegans Mouse Biotin ICC, IF, IP, IHC, ELISA, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Grp75 Monoclonal Antibody, Clone S52A-42 . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Mouse Anti-Grp75 Monoclonal Antibody  at 1:100 for 12 hours at 4°C. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Mitochondria. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-Grp75 Antibody. (C) Composite. Western Blot analysis of Human HeLa cell lysates showing detection of Grp75 protein using Mouse Anti-Grp75 Monoclonal Antibody, Clone S52A-42 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Grp75 Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 2 to 3 Days
$426.80
Details

HSPA9 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HSPA9 Antibodies

  1. Caenorhabditis elegans (C. elegans) Monoclonal HSPA9 Primary Antibody for ICC, IF - ABIN361740 : Kaul, Wadhwa, Komatsu, Sugimoto, Mitsui: On the cytosolic and perinuclear mortalin: an insight by heat shock. in Biochemical and biophysical research communications 1993 (PubMed)
    Show all 12 references for 361740

  2. Human Polyclonal HSPA9 Primary Antibody for EIA, IF - ABIN784589 : Leustek, Dalie, Amir-Shapira, Brot, Weissbach: A member of the Hsp70 family is localized in mitochondria and resembles Escherichia coli DnaK. in Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)
    Show all 10 references for 784589

  3. Human Polyclonal HSPA9 Primary Antibody for EIA, WB - ABIN952636 : Li, Xu, Ling, Yang, Wang, Li, Zhou, Wang, Liu: mot-2-Mediated cross talk between nuclear factor-B and p53 is involved in arsenite-induced tumorigenesis of human embryo lung fibroblast cells. in Environmental health perspectives 2010 (PubMed)
    Show all 5 references for 952636

  4. Cow (Bovine) Polyclonal HSPA9 Primary Antibody for IP, IHC - ABIN2779292 : Shi, Liu, Zhang, Qin, Zhang, Li, Chen: [Cloning and sequence analysis of the Meq gene of 4 Marek's disease virus isolates from China]. in Bing du xue bao = Chinese journal of virology / [bian ji, Bing du xue bao bian ji wei yuan hui] 2008 (PubMed)
    Show all 2 references for 2779292

  5. Caenorhabditis elegans (C. elegans) Monoclonal HSPA9 Primary Antibody for ICC, IF - ABIN2481675 : Schneider, Berthold, Bauer, Dietmeier, Guiard, Brunner, Neupert: Mitochondrial Hsp70/MIM44 complex facilitates protein import. in Nature 1994 (PubMed)

More Antibodies against HSPA9 Interaction Partners

Xenopus laevis Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. Hspa9 is an important mediator for pronephros development through modulation of pax8 (show PAX8 Antibodies). Mitochondrial functions of hspa9 are likely to be involved in specification of pronephric cell fate.

Human Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. these findings indicate that reduced levels of HSPA9 may contribute to TP53 (show TP53 Antibodies) activation and increased apoptosis observed in del(5q)-associated MDS (show PAFAH1B1 Antibodies).

  2. phosphorylation by ERK (show EPHB2 Antibodies) also regulates the association of HIF-1alpha (show HIF1A Antibodies) with a so-far-unknown interaction partner identified as mortalin (also known as GRP75 and HSPA9), which mediates non-genomic involvement of HIF-1alpha (show HIF1A Antibodies) in apoptosis.

  3. mortalin is an oncogenic factor.

  4. endocytosis vesicle enrichment of GRP75 by mitochondria trafficking upregulates clathrin-independent endocytosis through an actin cytoskeleton reorganization mechanism mediated by the concurrent activation of Cdc42 (show CDC42 Antibodies) and RhoA (show RHOA Antibodies).

  5. Mortalin is up-regulated in non-small cell lung cancer, and it may be a potential biomarker of prognostic evaluation and a molecular therapeutic target for patients with early stage of non-small cell lung cancer

  6. the mitochondrial stress chaperone mortalin is crucial for melanogenesis. the hyperpigmented keloid skin possesses significantly higher level of mortalin expression. mortalin is increased during oxidative stress and drug-induced melanogenesis. overexpression of mortalin causes an increase in pigmentation and its compromise leads to reduction in melanin content.

  7. These findings suggest a regulatory role of human miRNA pathway especially GRP75 protein and hsa (show CD24 Antibodies)-mir (show MLXIP Antibodies)-126 in dengue virus replication.

  8. UBXN2A binds to mortalin's binding pocket within the substrate-binding domain of mortalin. UBXN2A increases stability of p53 (show TP53 Antibodies) protein targeted by the mortalin-CHIP E3 ubiquitin ligase (show MUL1 Antibodies).

  9. Thus Hspa9 regulates erythroid differentiation through ISC cluster assembly, providing a pathophysiological mechanism for an MDS (show PAFAH1B1 Antibodies) subtype characterized by HSPA9 haploinsufficiency

  10. Study shows that Mortalin is upregulated in breast cancer, and may be a useful poor prognostic biomarker for patients with breast cancer.

Mouse (Murine) Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. Thus Hspa9 regulates erythroid differentiation through ISC cluster assembly, providing a pathophysiological mechanism for an MDS (show MECOM Antibodies) subtype characterized by HSPA9 haploinsufficiency

  2. This study demonstred that Mortalin expression in brain astrocytes.

  3. data imply a role for Hspa9 in B lymphopoiesis and Stat5 (show STAT5A Antibodies) activation downstream of IL-7 (show IL7 Antibodies) signaling

  4. Matrin 3 (show MATR3 Antibodies) interacts specifically with the heat shock proteins glucose-regulated protein 78 (show HSPA5 Antibodies), GRP75 and glutathione S-transferase (show GSTa2 Antibodies) pi isoform 2.

  5. down-regulation of mortalin may potentiate Abeta (show APP Antibodies)-mediated mitochondrial fragmentation and dysfunction in AD.

  6. the mortalin/DJ-1 (show PARK7 Antibodies) complex guards against mitochondrial oxidative stress and is indispensable for the maintenance of hematopoietic stem cells

  7. Inflammatory response of microglial cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein (show HSP90B1 Antibodies) 75/mortalin.

  8. Knockdown of Hspa9 results in a decrease in hematopoietic progenitors resulting in myelodysplastic syndromes.

  9. Data show that RNAi-mediated down-regulation of GRP75 and GRP75-blocking antibodies, both of which inhibited macromolecular endocytosis.

  10. The asymmetric segregation of mortalin in the bipotent cell line and its uniform distribution in a committed, lineage-restricted cell line raises the possibility that it may play a role in cell fate determination

HSPA9 Antigen Profile

Protein Summary

This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.

Gene names and symbols associated with HSPA9

  • heat shock 70kDa protein 9 (mortalin) (hspa9-a) antibody
  • heat shock 70kDa protein 9 (mortalin) (hspa9) antibody
  • heat shock 70kDa protein 9 (mortalin) (HSPA9) antibody
  • stress-70 protein, mitochondrial-like (HSPA9) antibody
  • heat shock protein 9 (Hspa9) antibody
  • 74kDa antibody
  • Csa antibody
  • GRP-75 antibody
  • Grp75 antibody
  • Hsc74 antibody
  • Hsp74 antibody
  • Hsp74a antibody
  • hspa9 antibody
  • Hspa9a antibody
  • HSPA9B antibody
  • Mortalin antibody
  • MOT antibody
  • Mot-2 antibody
  • Mot2 antibody
  • Mthsp70 antibody
  • MTHSP75 antibody
  • Pbp74 antibody

Protein level used designations for HSPA9

heat shock 70kDa protein 9 (mortalin) , heat shock 70kDa protein 9B , Stress-70 protein, mitochondrial-like protein , heat shock 70 kDa protein 9B , stress-70 protein, mitochondrial , GRP-75 , heat shock 70 kDa protein 9 , 75 kDa glucose-regulated protein , stress-70 protein, mitochondrial-like , heat shock 70kD protein 9B , mortalin, perinuclear , mortalin-2 , p66-mortalin , peptide-binding protein 74 , GRP 75 , heat shock 70kDa protein 9B (mortalin-2) , C3H-specific antigen , heat shock protein 9A , heat shock protein cognate 74 , heat shock protein, 74 kDa, A , heat shock protein, A , p66 MOT , PBP74 , heat shock 70kDa protein 9A , mortalin , mtHSP70 , 70 kDa heat shock protein , Heat shock 70 kDa protein 9

GENE ID SPECIES
379314 Xenopus laevis
407910 Xenopus (Silurana) tropicalis
577721 Strongylocentrotus purpuratus
714506 Macaca mulatta
100020208 Monodelphis domestica
100034032 Equus caballus
100173869 Pongo abelii
100406895 Callithrix jacchus
100521183 Sus scrofa
100590864 Nomascus leucogenys
416183 Gallus gallus
3313 Homo sapiens
517535 Bos taurus
474697 Canis lupus familiaris
15526 Mus musculus
291671 Rattus norvegicus
100689405 Cricetulus griseus
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