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anti-Heat Shock Factor 1 (HSF1) Antibodies

DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse HSF1 HSF1 15499 P38532
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More Antibodies against Heat Shock Factor 1 Interaction Partners

Mouse (Murine) Heat Shock Factor 1 (HSF1) interaction partners

  1. have demonstrated that the levels of HSF1 and heat shock proteins are significantly reduced in affected neuronal tissues from a TDP-43 (show TARDBP Antibodies) transgenic mouse model of amyotrophic lateral sclerosis and patients with sporadic amyotrophic lateral sclerosis.

  2. HSF-1 ablation not only eliminates heat shock response, but it also transcriptionally up-regulates CYP7A1 (show CYP7A1 Antibodies) and MDR1/P-gp (show ABCB4 Antibodies) axis in WD-diet fed HSF-1(-/-)/LDLr (show LDLR Antibodies)(-/-) mice to reduce atherosclerosis.

  3. Role of HSF1 in heart failure.HSF1 up-regulation of AC6 (show ADCY6 Antibodies).

  4. Findings suggest that PGC1alpha protects against hyperthermia by cooperating with HSF1 in the induction of a transcriptional program devoted to the cellular protection from thermal insults.

  5. Heat stress-associated increase in skeletal muscle mass may be induced by heat shock transcription factor 1 (HSF1) and/or HSF1-mediated stress response that activates muscle satellite cells and Akt (show AKT1 Antibodies)/p70S6K (show RPS6KB1 Antibodies) signalling pathway

  6. Defective Hsf1 inhibits the growth of fibrosarcoma derived from simian virus 40/T antigentransformed mouse embryonic fibroblasts.

  7. Suggest that the early activation of Hsf1 dependent cell stress pathway by mono-allelic mutations in APC (show APC Antibodies) can affect cell programming in a way that contributes to cancer onset.

  8. The pharmacological activation of HSF1 promotes thermogenic and mitochondrial gene programs in brown and beige (show LYST Antibodies) cells and in skeletal muscle, with profound impact on metabolic parameters.

  9. HSF1 is required for myocardial fibrosis in ISO-treated mice, and the underlying molecular mechanism may involve the regulation of HSP47 (show SERPINH1 Antibodies).

  10. Authors have concluded that at the physiological temperature HSF1 and HSF2 cooperate in spermatogenic cells. However, temperature elevation causes remodeling of chromatin binding and interactions between HSFs are disrupted.

Heat Shock Factor 1 (HSF1) Antigen Profile

Protein Summary

DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.

Gene names and symbols associated with HSF1

  • heat shock factor 1 (Hsf1) antibody
  • AA960185 antibody

Protein level used designations for HSF1

HSF 1 , HSTF 1 , heat shock factor protein 1 , heat shock transcription factor 1

15499 Mus musculus
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