anti-Heat Shock Factor Protein 1 (HSF1) Antibodies

The product of HSF1 is a heat-shock transcription factor. Additionally we are shipping HSF1 Kits (53) and HSF1 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSF1 15499 P38532
HSF1 3297 Q00613
HSF1 79245  
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Top anti-HSF1 Antibodies at antibodies-online.com

Showing 10 out of 496 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-HSF1 Antibody Titration: </b>0.06125ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>SP2/0 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-HSF1 Antibody Titration: </b>0.0625ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-HSF1 <br /> Antibody Titration: 0.0625 µg/mL ELISA Titer: 1:12500 <br /> Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-HSF1 Antibody Titration: </b>5.0ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>NIH/3T3 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using HSF1 (Phospho-Thr142) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of HSF1 polyclonal antibody (ABIN389069) in 293 cell line lysates. Non-sumoylated HSF1 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of HSF1 (arrow) using rabbit polyclonal HSF1 Antibody (Sumo) (ABIN389069). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HSF1 gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of HSF1 (arrow) using rabbit polyclonal HSF1 Antibody (N-term) (ABIN658110). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HSF1 gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-HSF1 Polyclonal Antibody, Unconjugated (ABIN703676) at 1:200 followed by conjugation to the secondary antibody and DAB staining Lane 1: mouse embryo lysates Lane 2:rat brain lysates probed with Anti HSF1 Polyclonal Antibody, Unconjugated (ABIN703676) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 57kD. Observed band size: 57kD, 105kD. 100 μL Log in to see 3 to 7 Days
$318.45
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti phospho-HSF1(Ser326) Polyclonal Antibody, Unconjugated (ABIN703466) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti phospho-HSF1(Ser326) Polyclonal Antibody, Unconjugated (ABIN703466) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$340.45
Details
Cow Rat Un-conjugated ELISA, GS, ICC, IF, IHC, IP, WB HSF1 (10H8), HeLa cells mitosis 100 μg Log in to see 2 to 3 Days
$309.10
Details

HSF1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-HSF1 Antibodies

  1. Human Polyclonal HSF1 Primary Antibody for IHC - ABIN966306 : Rafiee, Theriot, Nelson, Heidemann, Kanaa, Horowitz, Rogaczewski, Johnson, Ali, Shaker, Binion: Human esophageal microvascular endothelial cells respond to acidic pH stress by PI3K/AKT and p38 MAPK-regulated induction of Hsp70 and Hsp27. in American journal of physiology. Cell physiology 2006 (PubMed)
    Show all 4 Pubmed References

  2. Human HSF1 Primary Antibody for IHC - ABIN966305 : Takaki, Fujimoto, Sugahara, Nakahari, Yonemura, Tanaka, Hayashida, Inouye, Takemoto, Yamashita, Nakai: Maintenance of olfactory neurogenesis requires HSF1, a major heat shock transcription factor in mice. in The Journal of biological chemistry 2006 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal HSF1 Primary Antibody for IHC - ABIN966307 : Wang, Grammatikakis, Siganou, Calderwood: Regulation of molecular chaperone gene transcription involves the serine phosphorylation, 14-3-3 epsilon binding, and cytoplasmic sequestration of heat shock factor 1. in Molecular and cellular biology 2003 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal HSF1 Primary Antibody for ELISA, WB - ABIN561373 : Scott, Nogueira, Heffernan, van Doorn, Dhakal, Hanna, Min, Jaskelioff, Xiao, Wu, Cameron, Perry, Zeid, Feinberg, Kim, Vande Woude, Granter, Bosenberg, Chu, DePinho, Rimm, Chin: Proinvasion metastasis drivers in early-stage melanoma are oncogenes. in Cancer cell 2011 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal HSF1 Primary Antibody for GS, ICC - ABIN268500 : Rogers, Morris, Wheatley, Archer, McCoin, White, Wilson, Meers, Koch, Britton, Thyfault, Geiger: Deficiency in the Heat Stress Response Could Underlie Susceptibility to Metabolic Disease. in Diabetes 2016 (PubMed)

  6. Human Polyclonal HSF1 Primary Antibody for IF (p), IHC (p) - ABIN703466 : Evert, Frau, Tomasi, Latte, Simile, Seddaiu, Zimmermann, Ladu, Staniscia, Brozzetti, Solinas, Dombrowski, Feo, Pascale, Calvisi: Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value. in British journal of cancer 2013 (PubMed)

  7. Human Polyclonal HSF1 Primary Antibody for IF (p), IHC (p) - ABIN703676 : Zhang, He, Lu, Bian, Yang, Fu, Wu, Li: HSF1 Relieves Amyloid-?-Induced Cardiomyocytes Apoptosis. in Cell biochemistry and biophysics 2015 (PubMed)

  8. Human Polyclonal HSF1 Primary Antibody for IHC, ELISA - ABIN1532015 : Tamaru, Hattori, Ninomiya, Kawamura, Varès, Honda, Mishra, Wang, Benjamin, Sassone-Corsi, Ozawa, Takamatsu: ROS Stress Resets Circadian Clocks to Coordinate Pro-Survival Signals. in PLoS ONE 2013 (PubMed)

  9. Human Polyclonal HSF1 Primary Antibody for ICC, IF - ABIN2482061 : Asai, Kawashima, Katagiri, Takeuchi, Tohnai, Ohtsuka: Protective effect of a molecular chaperone inducer, paeoniflorin, on the HCl- and ethanol-triggered gastric mucosal injury. in Life sciences 2011 (PubMed)
    Show all 12 Pubmed References

More Antibodies against HSF1 Interaction Partners

Caenorhabditis elegans (C. elegans) Heat Shock Factor Protein 1 (HSF1) interaction partners

  1. These functions of HPK-1 (show MAP4K1 Antibodies)/HSF-1 undergo rapid down-regulation once animals reach reproductive maturity. We show that HPK-1 (show MAP4K1 Antibodies) fortifies proteostasis and extends longevity by an additional independent mechanism: induction of autophagy.

  2. Diminution in phenotypic variation for both gene expression and life span at 25 degrees C may be a consequence of low level hsf-1-dependent expression of HSP-16.2 and other chaperones at the higher temperature.

  3. We demonstrate that while DAF-16/FOXO is dispensable, the age-dependent suppression of cilia phenotypes in IFT mutants requires cell-autonomous functions of the HSF1 heat shock factor and the Hsp90 chaperone

  4. HSF-1 is a codeterminant of both alcohol and nicotine sensitivity in C. elegans and that this phenotype requires the small HSP, HSP-16.48. HSP-16.48 function in drug sensitivity is unrelated to a chaperone action during the heat shock stress response.

  5. Heat-stress-enhanced ascaroside production appears to be mediated at least in part by HSF-1, which seems to be important in adaptation strategies for coping with heat stress in this nematode.

  6. FUdR treatment can modulate the HSR and proteostasis, and should be used with caution when used to inhibit reproduction.

  7. Excitation of the AFD thermosensory neurons is sufficient to activate HSF1 in another cell, even in the absence of temperature increase. Excitation of the AFD thermosensory neurons enhances serotonin release.

  8. hsf-1 RNAi suppressed the restoration of thrashing reduced by heat stress. In contrast, hsf-1 knockdown cancelled prevention of movement reduction in a daf-2 (show DAF2 Antibodies) mutant, but didn't suppress thrashing restoration in daf-2 (show DAF2 Antibodies) mutant.

  9. we engaged C. elegans mutants and identified that the p38 MAPK (show MAPK14 Antibodies) signaling, insulin (show INS Antibodies)/IGF-1 (show IGF1 Antibodies) signaling (IIS), and HSF-1 play pivotal roles in the WCESP-mediated host immune response

  10. HSF-1 has a prominent role in cytoskeletal integrity, ensuring cellular function during stress and aging. Overexpression of pat-10 increased actin filament stability, thermotolerance, and longevity, indicating that in addition to chaperone regulation, HSF-1 has a prominent role in cytoskeletal integrity, ensuring cellular function during stress and aging.

Mouse (Murine) Heat Shock Factor Protein 1 (HSF1) interaction partners

  1. HSF1 plays an important role in the occurrence of UVR-B-induced cataracts, possibly via regulation of HSPs such as HSP25 (show HSPB1 Antibodies).

  2. Targeted deletion of HSF1 results in changes of locomotor function associated with changes in cerebellar calbindin (show CALB1 Antibodies) protein levels. These findings suggest a role of HSF1 in regular Purkinje cell calcium homeostasis.

  3. this study shows that HSF1 overexpression protects against TDP-43 (show TARDBP Antibodies) pathology by upregulation of chaperones, especially HSP70 (show HSP70 Antibodies), rather than enhancing autophagy

  4. Acetylation of the protein triggers TDP-43 (show TARDBP Antibodies) pathology in cultured cells and mouse skeletal muscle, which can be cleared through an HSF1-dependent chaperone mechanism that disaggregates the protein.

  5. These findings provide insight into the role of HSF1 in Leydig cell steroidogenesis, suggesting that it maintains cholesterol transport by recovering StAR under chronic heat stress.

  6. In mammalian cell lines, only heat shock-induced but not basal expression of chaperones is dependent on the mammalian Hsf1 homolog.

  7. Upregulating HSF1 relieves the tau toxicity in N2a-TauRD DeltaK280 by reducing CHOP (show DDIT3 Antibodies) and increasing HSP70 (show HSP70 Antibodies) a5 (BiP/GRP78 (show HSPA5 Antibodies)). Our work reveals how the bidirectional crosstalk between the two stress response systems promotes early tau pathology and identifies HSF1 being one likely key player in both systems.

  8. HSF1 translationally augments the proteotoxic stress response.

  9. HSF1 as a central regulator of cellular bioenergetics.

  10. have demonstrated that the levels of HSF1 and heat shock proteins are significantly reduced in affected neuronal tissues from a TDP-43 (show TARDBP Antibodies) transgenic mouse model of amyotrophic lateral sclerosis and patients with sporadic amyotrophic lateral sclerosis.

Human Heat Shock Factor Protein 1 (HSF1) interaction partners

  1. We found that HSF1 activation mediated by 1,4-NQ upregulated downstream genes, such as HSPA6 (show HSPA6 Antibodies). The results suggest that activation of the HSP90 (show HSP90 Antibodies)-HSF1 signal transduction pathway mediated by 1,4-NQ protects cells against 1,4-NQ and that per/polysulfides can diminish the reactivity of 1,4-NQ by forming sulfur adducts.

  2. casein kinase 1 (show CSNK1A1 Antibodies) phosphorylates the SQSTM1 (show SQSTM1 Antibodies) S349 residue when harmful proteins accumulate under HSF1 stress

  3. Evidence for the essential function of HSF1 in the transcriptional activation of TERRA (show DMRT2 Antibodies) and in telomere protection upon stress.

  4. Acetylation of the protein triggers TDP-43 (show TARDBP Antibodies) pathology in cultured cells and mouse skeletal muscle, which can be cleared through an HSF1-dependent chaperone mechanism that disaggregates the protein.

  5. Low glucose culture hampered typical epithelial-mesenchymal transition-like morphological change, "cadherin switching," and cell migration of hepatocellular carcinoma cells through inducing persistent down-regulation of HSF1, resulting in direct inhibition of snail1 (show SNAI1 Antibodies) expression.

  6. piR (show PIR Antibodies)-823 increased the transcriptional activity of HSF1, the common transcription factor of HSPs, by binding to HSF1 and promoting its phosphorylation at Ser326.

  7. Reporter assay showed that HSF1 increased the transcriptional activity of ATG4B (show ATG4B Antibodies) gene promoter, and chromatin immunoprecipitation assay verified that HSF1 bound to the site (-1429 to -1417) in ATG4B (show ATG4B Antibodies) gene promoter region.

  8. Knockdown of HSF1 reduced the proliferation, migration and invasion of osteosarcoma cells, while overexpression of HSF1 promoted the proliferation, migration and invasion of osteosarcoma cells.

  9. Data suggest that hnRNPK plays role in heat shock response of cells by regulating HSF1; hnRNPK inhibits HSF1 activity, resulting in reduced expression of HSP27 and HSP70 mRNAs; hnRNPK also down-regulates binding of HSF1 to heat shock response element. (hnRNPK = heterogeneous-nuclear ribonucleoprotein K; HSF1 = heat shock transcription factor 1; HSP = heat-shock protein)

  10. Studies indicate correlations between heat shock transcription factor 1 (HSF1) activity and the incidence of several cancer types.

Cow (Bovine) Heat Shock Factor Protein 1 (HSF1) interaction partners

  1. As the 4693-T mutation caused the disruption of microRNA target binding (resulting in the relief of the transcriptional repression), the HSF1 gene is useful in dairy cattle thermal tolerant breeding.

Chlamydomonas reinhardtii (C. reinhardtii) Heat Shock Factor Protein 1 (HSF1) interaction partners

  1. HSF1 is a key trans-acting factor for counteracting transgene promoter silencing in Chlamydomonas.

  2. Data show that activated HSF1 and CRR1 transcription factors mediate the acetylation of histones H3/4, nucleosome eviction, remodeling of the H3K4 mono- and dimethylation marks, and transcription initiation/elongation.

  3. data suggest that HSF1 is a key regulator of the stress response in Chlamydomonas

Rabbit Heat Shock Factor Protein 1 (HSF1) interaction partners

  1. Data suggest that myocardial HSF1 and HSP70 (show HSP70 Antibodies) (70 kDa heat-shock protein (show HSPA9 Antibodies)) can be up-regulated by dietary factors (here, antioxidant taurine as a dietary supplement administered to counteract effects of atherogenic diet).

Pig (Porcine) Heat Shock Factor Protein 1 (HSF1) interaction partners

  1. The results indicate that Heat shock protein 70 (Hsp70) mediates distinct stress-related functions in different tissues during transportation. Heat shock factor-1 (HSF-1) levels were reduced at 1 and 4 h only in the hearts of transported pigs.

Zebrafish Heat Shock Factor Protein 1 (HSF1) interaction partners

  1. The transcriptional up-regulation of unc45b, hsp90aa1.1 and smyd1b is specific to zebrafish mutants with myosin folding defects, and is not triggered in other zebrafish myopathy models

  2. data suggest that HSF1 is involved in regulating constitutive lens specific expression of hsp70 (show HSPA1A Antibodies) in the embryonic zebrafish

HSF1 Antigen Profile

Protein Summary

The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene.

Gene names and symbols associated with HSF1

  • heat shock factor (hsf1) antibody
  • Heat Shock Factor (hsf-1) antibody
  • heat shock factor 1 (Hsf1) antibody
  • heat shock transcription factor 1 (HSF1) antibody
  • heat shock transcription factor 1 (Hsf1) antibody
  • heat shock transcription factor 1 (hsf1) antibody
  • heat shock transcription factor 1 S homeolog (hsf1.S) antibody
  • AA960185 antibody
  • HSF antibody
  • HSF1 antibody
  • hsf1a antibody
  • hsf1b antibody
  • HSF1c antibody
  • hstf1 antibody
  • xhsf1 antibody
  • zHSF1a antibody
  • zHSF1b antibody

Protein level used designations for HSF1

heat shock factor protein , HSTF , heat shock transcription factor , Heat Shock Factor family member (hsf-1) , HSF 1 , HSTF 1 , heat shock factor protein 1 , heat shock transcription factor 1

GENE ID SPECIES
399268 Xenopus laevis
173078 Caenorhabditis elegans
15499 Mus musculus
3297 Homo sapiens
506235 Bos taurus
79245 Rattus norvegicus
5720002 Chlamydomonas reinhardtii
100350887 Oryctolagus cuniculus
101787582 Cavia porcellus
475124 Canis lupus familiaris
100511321 Sus scrofa
420362 Gallus gallus
58123 Danio rerio
779172 Xenopus laevis
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