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heat shock protein; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons.
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Cow (Bovine) Polyclonal HSPA4 Primary Antibody for IHC, WB - ABIN2481920
Lee-Yoon, Easton, Murawski, Burd, Subjeck: Identification of a major subfamily of large hsp70-like proteins through the cloning of the mammalian 110-kDa heat shock protein. in The Journal of biological chemistry 1995
Show all 3 references for ABIN2481920
Cow (Bovine) Polyclonal HSPA4 Primary Antibody for IHC, WB - ABIN2481918
Dragovic, Broadley, Shomura, Bracher, Hartl: Molecular chaperones of the Hsp110 family act as nucleotide exchange factors of Hsp70s. in The EMBO journal 2006
Show all 3 references for ABIN2481918
Cow (Bovine) Polyclonal HSPA4 Primary Antibody for IHC, WB - ABIN2481913
Nakamura, Fujimoto, Yasuda, Takeda, Akira, Hatayama, Takagi, Nozaki, Hosokawa, Nagata: Targeted disruption of Hsp110/105 gene protects against ischemic stress. in Stroke; a journal of cerebral circulation 2008
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Dog (Canine) Monoclonal HSPA4 Primary Antibody for IF, IP - ABIN968011
Moore, Scheinman, Bellgrau: The identification of a novel T cell activation state controlled by a diabetogenic gene. in Journal of immunology (Baltimore, Md. : 1950) 2001
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Data show that heat shock protein 70 (HSP70 (show HSP70 Antibodies)) induction by geranylgeranylacetone (GGA) was effective against N-methyl-N-nitrosourea (MNU-induced photoreceptor cell loss.
Upregulation of HSPA4 would control apoptosis of inflammatory cells and immune response in the gut (show GUSB Antibodies), which might develop treatment resistance in inflammatory bowel disease.
regulates the expression of SDF-1 (show CXCL12 Antibodies) and Twist in fibroblasts, thereby controlling gastric ulcer healing
Inhibition of Apg-2 by shRNA not only decreased cell proliferation, but also induced cell apoptosis in BCR/ABL (show ABL1 Antibodies) positive chronic myeloid leukemia (show BCL11A Antibodies) cells (BaF3-BCR/ABL (show ABL1 Antibodies), BaF3-BCR/ABL (show ABL1 Antibodies)(T315I)).
PSMB8 (show PSMB8 Antibodies), ALDH1A1 (show ALDH1A1 Antibodies), and HSPA4 were identified to be located in ovarian tissues, to regulate 12 cellular pathways, and demonstrate age-dependent dynamic changes in expression profiling.
HSPA4L (show HSPA4L Antibodies) and HSPA4 collaborate in embryonic lung maturation, which is necessary for adaptation to air breathing at birth.
study demonstrates that lack of HSPA4 leads to cardiac hypertrophy and fibrosis; data reveal the distinct, non-redundant role of HSPA4 in the protein quality control that maintains the proper protein folding and homeostasis in cardiomyocytes
Data suggest HSPA4 is required for spermatogenesis. All homozygous HSPA4-deficient mice are apparently healthy; HSPA4 is expressed as early as E13.5 in male gonad; increased number of HSPA4-deficient males are infertile, whereas females are fertile.
Findings provide in vivo evidence that Hsp110 (show HSPH1 Antibodies) plays a critical function in tau phosphorylation state through maintenance of efficient PP2A (show PPP2R2B Antibodies) activity, confirming its role in pathogenesis of Alzheimer's disease and other tauopathies.
Overexpression of Apg-2 in proB-BCR/ABL (show ABL1 Antibodies) cells increases cell proliferation and protects cells from oxidative damage.
heat shock protein\; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons
heat shock 70 kDa protein 4
, heat shock 70-related protein APG-2
, heat shock protein, 110 kDa
, ischemia responsive 94 kDa protein