anti-Heat Shock Protein 70 (HSP70) Antibodies

heat shock protein\; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons [RGD, Feb 2006].. Additionally we are shipping HSP70 Kits (77) and HSP70 Proteins (34) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Human HSP70 HSP70 3308 P34932
Anti-Mouse HSP70 HSP70 15511 P17879
Anti-Rat HSP70 HSP70 266759 O88600
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Top anti-HSP70 Antibodies at antibodies-online.com

Showing 10 out of 786 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Caenorhabditis elegans Mouse Un-conjugated AA, BI, ELISA, FACS, ICC, IEM, IF, IHC, WB Hsp70 (C92) Mouse Melanoma. Hsp70 (C92), cell lines. 50 μg Log in to see 2 to 3 Days
$225.50
Details
Amphibian Mouse Un-conjugated AA, ICC, IF, IHC, IP, WB Hsp70 (2A4), rat tissue copy. 100 μg Log in to see 2 to 3 Days
$365.20
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Generously provided by Merlin Levine from National Institutes of Health as part of the Bioss Discovery Program. Mouse brain labeled with Anti-HSP70 Polyclonal Antibody, Unconjugated (ABIN725360) at 1:100 overnight. The secondary antibody was AlexaFluor 555 goat anti mouse IgG1 used at 1:250 for one hour. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Hsp70 on a HeLa cell lysate (Human cervical epitheloid carcinoma, ATCC CCL-2.2). Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the anti-Hsp70 antibody. Immunofluorescence staining of HeLa cells (Human cervical epitheloid carcinoma, ATCC CCL-2.2). 50 μg Log in to see 6 to 8 Days
$154.07
Details
Cow Rabbit Un-conjugated IHC, WB 100 μg Log in to see 2 to 3 Days
$265.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB The anti-HSP70 Pab (ABIN388133) is used in Western blot to detect HSP70 in mouse liver tissue lysate (LEFT) and HL60 cell lysate (RIGHT). Western blot analysis of anti-hHSP70 Pab (ABIN388133) in HL60 cell line lysates (35 µg/lane).hHSP70(arrow) was detected using the purified polyclonal antibody (1:60dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 6 to 8 Days
$500.50
Details
Amphibian Mouse Un-conjugated AA, ICC, IF, IHC, IP, WB Hsp70 (3A3), Artemia franciscanna  Picture courtesy of Alison King. 100 μg Log in to see 2 to 3 Days
$365.20
Details
Human Chicken Un-conjugated ICC, IF, ELISA, WB Hsp70 (Chicken), Hela Cell Lysate. 100 μg Log in to see 2 to 3 Days
$380.60
Details
Carp Mouse FITC FACS   0.2 mg Log in to see 12 to 15 Days
$375.38
Details

HSP70 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-HSP70 Antibodies

  1. Caenorhabditis elegans (C. elegans) Monoclonal HSP70 Primary Antibody for AA, BI - ABIN361707 : Boorstein, Ziegelhoffer, Craig: Molecular evolution of the HSP70 multigene family. in Journal of molecular evolution 1994 (PubMed)
    Show all 44 Pubmed References

  2. Cow (Bovine) Monoclonal HSP70 Primary Antibody for IHC (fro), IHC (p) - ABIN3043650 : Fan, Jiang, Yang, Liu, Song, Pan: Effects of adrenergic agents on stress-induced brain microstructural and immunochemical changes in adult male Wistar rats. in Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2011 (PubMed)
    Show all 7 Pubmed References

  3. Algae (Desmodesmus subspicatus) Polyclonal HSP70 Primary Antibody for IP, WB - ABIN2487328 : Muralidharan, Oksman, Pal, Lindquist, Goldberg: Plasmodium falciparum heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial fevers. in Nature communications 2012 (PubMed)
    Show all 7 Pubmed References

  4. Plasmodium falciparum Polyclonal HSP70 Primary Antibody for ICC, IF - ABIN361730 : Bork, Sander, Valencia: An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 10 Pubmed References

  5. Fish Polyclonal HSP70 Primary Antibody for WB - ABIN361870 : Brown, Hong-Brown, Doxsey, Welch: Molecular chaperones and the centrosome. A role for HSP 73 in centrosomal repair following heat shock treatment. in The Journal of biological chemistry 1996 (PubMed)
    Show all 8 Pubmed References

  6. Human Monoclonal HSP70 Primary Antibody for IP, WB - ABIN967447 : Craig, Gross: Is hsp70 the cellular thermometer? in Trends in biochemical sciences 1991 (PubMed)
    Show all 3 Pubmed References

  7. Rat (Rattus) Polyclonal HSP70 Primary Antibody for ELISA, WB - ABIN1574053 : Pons, Ferrebuz, Quiroz, Romero-Vasquez, Parra, Johnson, Rodriguez-Iturbe: Immune reactivity to heat shock protein 70 expressed in the kidney is cause of salt-sensitive hypertension. in American journal of physiology. Renal physiology 2013 (PubMed)
    Show all 3 Pubmed References

  8. Human Polyclonal HSP70 Primary Antibody for IF (p), IHC (p) - ABIN725360 : Wang, Wang, Feng, Mi, Chen, Shang, Chen: Comparative vesicle proteomics reveals selective regulation of protein expression in chestnut blight fungus by a hypovirus. in Journal of proteomics 2012 (PubMed)
    Show all 2 Pubmed References

  9. Human Monoclonal HSP70 Primary Antibody for IF, IHC - ABIN966316 : Pang: Hospital-based dermatology: my personal journey. in Singapore medical journal 2009 (PubMed)
    Show all 2 Pubmed References

  10. Chicken Monoclonal HSP70 Primary Antibody for IF, IP - ABIN968060 : Hunt, Morimoto: Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70. in Proceedings of the National Academy of Sciences of the United States of America 1985 (PubMed)
    Show all 2 Pubmed References

More Antibodies against HSP70 Interaction Partners

Human Heat Shock Protein 70 (HSP70) interaction partners

  1. verified the interaction of cellular chaperon HSP70 with Porcine reproductive and respiratory syndrome virus NSP12, and demonstrated that NSP12 could recruit HSP70 to maintain its own stability and benefit for the virus replication

  2. Modulatory action of extracellular HSP70 on A549 inflammatory response through RAGE (show AGER Antibodies) was able to evoke important expression changes in monocyte, showing its relevance in influencing the interaction between cancer and immune system cell.

  3. Here the authors show that in budding yeast, Hsf1 (show HSF1 Antibodies) basally associates with the chaperone Hsp70 and this association is transiently disrupted by heat shock, providing the first evidence that a chaperone repressor directly regulates Hsf1 (show HSF1 Antibodies) activity.

  4. Pharmacological or genetic activation of heat shock protein 70 (Hsp70) protects against loss of parkin (show PARK2 Antibodies) Function. Heat shock protein members may act as compensatory factors for parkin (show PARK2 Antibodies) loss of function and that the exploitation of these factors may be of potential therapeutic value.

  5. targeting the Hsp70 induction in Hsp90 (show HSP90 Antibodies) inhibitor-treated cancer cells and tumor vasculature cells may beneficially enhance the radiosensitizing effect

  6. The interaction of Fas receptor (show FAS Antibodies) with FasL (show FASL Antibodies) leads to an activation of the Tag7 (show PGLYRP1 Antibodies)-Hsp70 complex in the lymphocyte membrane fraction, and here FasL (show FASL Antibodies) acts as a receptor that induces intracellular signaling in lymphocytes.An interaction of the MicA (show MICA Antibodies) stress ligand with the NKG2D (show KLRK1 Antibodies) receptor is necessary for the release of this cytotoxic complex

  7. Triptolide downregulates Sp1 (show PSG1 Antibodies) and HSP70 mRNA in gastric cancer cell lines.

  8. HSP70-TRIM32 (show TRIM32 Antibodies) complex is biochemically distinct from the previously characterized 14-3-3 (show YWHAQ Antibodies)-TRIM32 (show TRIM32 Antibodies) phospho-complex.

  9. There is overwhelming evidence that molecular chaperones such as Hsp27 (show HSPB1 Antibodies), Hsp70 and Hsp90 (show HSP90 Antibodies) are expressed at elevated levels in a wide range of cancers by stabilizing the mutated neoplasm proteins. (Review)

  10. HSP70 is required for the maintenance of a functional mitotic centrosome that supports the assembly of a bipolar mitotic spindle.

Tomato (Solanum lycopersicum) Heat Shock Protein 70 (HSP70) interaction partners

  1. Experimental evidence show: apoptozole forms aggregates under aqueous conditions that could interact with HSP70 proteins in a non-specific manner.

  2. Disrupts the Hsp70-Bag3 (show BAG3 Antibodies) interaction.

  3. Increased Hsp70 expression levels are associated with squamous cell carcinoma of the head and neck.

  4. Hsp70 and Hsp90 (show HSP90 Antibodies) chaperones coregulate heat shock gene expression within a network of mutual, but factor-specific, interactions with heat stress transcription factors.

  5. salicylic acid-mediated potentiation of Hsp70 is due to modulation of heat shock factors by salicylic acid.

Pig (Porcine) Heat Shock Protein 70 (HSP70) interaction partners

  1. There was a significant decrease in the systemic HSP70 levels of trauma groups (moderate and severe hemorrhage) when compared to the sham trauma group, which was significantly decreased compared to baseline values in severe hemorrhage over the entire time course.

  2. Host HSP70 and Classical swine fever virus NS5A protein complex formation is confirmed by coimmunoprecipitation and GST-pulldown studies.

  3. This study evaluated the expression of 70kDa (show RPS6KB1 Antibodies) heat shock proteins and the concentration of thiobarbituric acid reactive substances and nitric oxide ions as markers of oxidative stress in swine.

  4. This study revealed that HSP70 is an essential host factor required for the replication of porcine reproductive and respiratory syndrome virus.

  5. A specific interaction between Hsp70 and porcine circovirus type 2 Cap (capsid protein) was confirmed by colocalization by confocal microscopy and co-immunoprecipitation.

  6. This work investigated the expression of heat shock protein 70 by Western blot in swine liver. Animals in an intensive/indoor confinement system showed significantly higher HSP70 values compared with those in an extensive/outdoor system.

  7. The results indicate that Heat shock protein 70 (Hsp70) mediates distinct stress-related functions in different tissues during transportation. Heat shock factor-1 (HSF-1) levels were reduced at 1 and 4 h only in the hearts of transported pigs.

  8. These results indicated that the expression of Hsp70 in the intestinal piglets was upregulated by IUGR, and different intestinal sites had different responses to stress.

  9. Induction of tolerance to heat shock correlated with the induced expression of heat shock protein 70. HSP70 and compatible osmolytes have distinct roles in cellular adaptation to these stresses.

  10. HSP-70 is an endogenous protectant of which its actions may be unmasked and/or potentiated with exogenous administration before brain injury

Arabidopsis thaliana Heat Shock Protein 70 (HSP70) interaction partners

  1. ability of multiple unrelated Hsp70-binding elements to support protein import verified that the majority of TPs utilize an N-terminal Hsp70-binding domain during translocation and expand the mechanistic view of the import process

  2. temperature regulated expression of AtHSP70-4 may be mediated by cell cycle transcription factors and participate in plant acclimations to non-stress temperature changes

  3. This work describes a detailed quantitative interaction study between the novel plastidial chaperone receptor OEP61 and isoforms of the chaperone types Hsp70 and Hsp90 (show HSP90 Antibodies) using the optical method of total internal reflection ellipsometry.

  4. Hsp70-14 and Hsp70-15 silenced plants display an altered stomatal response and a constitutive heat stress phenotype.

  5. Chloroplasts have two chaperone systems facilitating protein translocation into the stroma: the cpHsc70 system and the Hsp93/Tic40 system.

  6. A working hypothesis is that Hsp70 has a defense-promoting activity(s) that HopI1 or high temperature can subvert.

  7. Hsc70-4 and CHIP were highly induced in ppi2 mutant plants, where they mediated the degradation of chloroplast-targeted precursors through the ubiquitin-26S proteasome (show Psmd4 Antibodies) system.

  8. The MAPK (show MAPK1 Antibodies)-EGR-1 (show EGR1 Antibodies)-HSP70 pathway regulates the cigarette smoke-induced inflammatory process.

Mouse (Murine) Heat Shock Protein 70 (HSP70) interaction partners

  1. interaction between BAG3 (show BAG3 Antibodies) and HSP70 is essential for BAG3 (show BAG3 Antibodies) to stabilize small heat shock proteins and maintain cardiomyocyte protein homeostasis

  2. Data show that Klotho (show KL Antibodies) protein is present in the heart, and reduced levels of myocardial Klotho (show KL Antibodies) in aging mice is accompanied by lower levels heat shock protein 70 (HSP70) in the myocardium.

  3. analysis of the intracellular pathways implicated in Hsp70 regulated signal transduction showed the involvement of both PI3K/AKT (show AKT1 Antibodies) and NF-kappaB (show NFKB1 Antibodies).

  4. HSPA1A (show HSPA1A Antibodies)/B induction is a novel approach to delay thrombus formation with minimal bleeding risk in knockout mice

  5. Hsp70 expression was observed trophoblast cells and decidual cells and was relatively constant throughout the pregnancy.

  6. The results of comparative analysis of interaction between the protein cytotoxic complex Tag 7 (show PGLYRP1 Antibodies)-Hsp70 and the Tag 7 (show PGLYRP1 Antibodies) component of this complex with TNFR1 (show TNFRSF1A Antibodies) receptor in solution and in tumor cells are presented.

  7. the protective effect of HSP70 may be associated with inhibition of NF-kappaB (show NFKB1 Antibodies) and stimulation of NOS (show NOS Antibodies)/NO signaling pathways

  8. activation of the HSP70-TLR4 (show TLR4 Antibodies) axis, stimulated at least in part by albumin (show ALB Antibodies), in the tubular cell is a newly identified mechanism associated with induction of tubulointerstitial inflammation.

  9. Studied the protein expression of BCL2 (show BCL2 Antibodies), FGF-R1, and HSP70 after short-time magnetic thermoablative tumor treatment using immunohistochemistry in a human BT474 breast cancer mouse xenograft model.

  10. Knockdown lines were created for specific DSBs in regions of the chromosome that are coding for HSPA1B (show HSPA1A Antibodies). Clonogenic cell survival was significantly lower in irradiated Hsp70 KD cells with low mHsp70 expression, than in ctrl cells.

Cow (Bovine) Heat Shock Protein 70 (HSP70) interaction partners

  1. A new SNP in the 3'-UTR (show UTS2R Antibodies) of the hsp 70-1 gene in Bos taurus and Bos indicus

  2. The purified 44-kD ATPase domain from HSP70 exhibited intrinsic ATP-ADP exchange activity and acid-stable autophosphorylation at Thr204.

  3. The effect of culture conditions on expression of heat shock protein 70 and Bax (show BAX Antibodies) protein in bovine blastocysts is reported.

  4. that HSC70 (show HSPA8 Antibodies) preconditioning (1) attenuates the TNF-alpha (show TNF Antibodies) response to endotoxin in macrophages in vitro, (2) induces cardiac functional tolerance to endotoxin and (3) reduces NF-kappaB (show NFKB1 Antibodies) activity, and TNF-alpha (show TNF Antibodies) and ICAM-1 (show ICAM1 Antibodies) levels in heart tissue.

  5. the presence of SNPs (C/- and G/T) in the 5'-UTR (show UTS2R Antibodies) region of inducible Hsp70.1 (show HSPA1A Antibodies) ameliorates HS response and tolerance to heat of bovine peripheral blood mononuclear cells

  6. This study showed that Hsp70 concentration is a reliable indicator of chronic stress but is not a reliable indicator of a single stressor when animals are exposed to multiple chronic stressors.

  7. Heat shock increased both HSP70 and IFNT expression in blastocysts.

  8. the promoter region of bovine hsp70.1 (show HSPA1A Antibodies) gene is polymorphic and may be useful in selection of dairy cows for relatively better thermotolerance and higher milk production.

  9. More DNMT1 (show DNMT1 Antibodies) mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (show ASCL2 Antibodies) mRNA was present at highest levels in transgenic SCNT embryos.

  10. In Sahiwal cattle the mRNA expression of HSP70 and its protein concentration were higher (P<0.05) during peak summer (44 degrees C) and winter (10 degrees C) as compared to Frieswal cattle. This investigation supports the earlier information on the higher adaptability of indigenous cattle breeds to hot and humid conditions compared to the crossbreds of temperate cattle breeds.

HSP70 Antigen Profile

Protein Summary

heat shock protein\; may have an important role following forebrain ischemia and may allow astrocytes to protect neurons

Gene names and symbols associated with HSP70

  • heat shock protein family A (Hsp70) member 4 (HSPA4) antibody
  • CG5834 gene product from transcript CG5834-RA (Hsp70Bbb) antibody
  • heat shock protein 70 (HSP70) antibody
  • heat shock protein family A (Hsp70) member 6 (HSPA6) antibody
  • heat shock 70kDa protein 2 (HSPA2) antibody
  • heat shock 70 kD protein cognate (HSP70) antibody
  • chloroplast heat shock protein 70-2 (cpHsc70-2) antibody
  • Heat shock protein 70 (Hsp 70) family protein (Hsp70-15) antibody
  • Hsp70 family chaperone (HSP70) antibody
  • Heat shock protein 70 (PCC7424_2419) antibody
  • Heat shock protein 70 (Isop_1041) antibody
  • Heat shock protein 70, putative (CGB_C3390W) antibody
  • Heat shock protein 70 (Bacsa_1698) antibody
  • heat shock protein 70 (dnaK-B) antibody
  • heat shock protein 70 (LOC100305036) antibody
  • heat shock protein 1B (Hspa1b) antibody
  • heat shock protein family A member 4 (Hspa4) antibody
  • heat shock cognate protein 70a (hsc70a) antibody
  • heat shock 70kDa protein 1A (HSPA1A) antibody
  • heat shock protein 1 (hsp1) antibody
  • Heat Shock Protein (hsp-70) antibody
  • heat shock cognate 70-kd protein (hsp70) antibody
  • APG-2 antibody
  • ARABIDOPSIS HEAT SHOCK PROTEIN 70 antibody
  • ATHSP70 antibody
  • CG5834 antibody
  • CG31354 antibody
  • chloroplast heat shock protein 70-2 antibody
  • cpHsc70-2 antibody
  • DmelCG5834 antibody
  • F19K16.12 antibody
  • F19K16_12 antibody
  • HEAT SHOCK PROTEIN 70 antibody
  • HEAT SHOCK PROTEIN 70-7 antibody
  • HS24/P52 antibody
  • hsc70 antibody
  • HSC70-7 antibody
  • hsc71 antibody
  • hsp68 antibody
  • Hsp70 antibody
  • Hsp70-1 antibody
  • HSP70-2 antibody
  • hsp70-5 antibody
  • Hsp70.1 antibody
  • hsp70B antibody
  • HSP70B' antibody
  • Hsp70Bb antibody
  • hsp70Bb-prime antibody
  • hsp70RY antibody
  • Hsp110 antibody
  • HSPA1 antibody
  • HSPA1B antibody
  • HSPA2 antibody
  • HSPA6 antibody
  • HSPH2 antibody
  • irp94 antibody
  • K9P8.5 antibody
  • K9P8_5 antibody
  • LOC100305036 antibody
  • RY antibody

Protein level used designations for HSP70

heat shock 70 kDa protein 4 , heat shock 70-related protein APG-2 , heat shock 70kD protein 4 , heat shock protein, 110 kDa , hsp70 RY , Hsp70Bbb , CG5834-PA , Hsp70Bbb-PA , heat shock 70 kDa protein 1 , Heat shock 70 kDa protein 6 , heat shock 70 kDa protein , heat shock 70 kDa protein B' , dnaK-type molecular chaperone , heat shock protein 70 , heat shock 70 kD protein cognate , hypothetical protein , Heat shock protein 70 , CF Hsp70 , Heat shock cognate 71 kDa protein , 68 kDa heat shock protein , heat shock 70 kDa protein 1B , heat shock 70kDa protein 1B , heat shock protein 70.1 , heat shock protein, 70 kDa 1 , ischemia responsive 94 kDa protein , HSP70 , heat shock 70kDa protein 8 , heat shock cognate 70 kDa protein , 70 kda heat shock protein-2 , HSP70.2 , chaperone , heat shock 70 kD protein 2 , heat shock 70 kDa protein 2 , heat-shock 70-kilodalton protein 1B , CL45_1 , CL45_1(648) , CL45_1_ov , Heat shock 70 kDa protein , heat shock protein 70 kDa , hsp 70-1 , npi119-hsp1 , heat shock 70 kDa protein 1A/1B , Heat shock cognate 70 kDa protein , heat shock cognate 70-kd protein

GENE ID SPECIES
3308 Homo sapiens
50022 Drosophila melanogaster
403612 Canis lupus familiaris
100134914 Solanum lycopersicum
396906 Sus scrofa
423504 Gallus gallus
692373 Bombyx mori
820438 Arabidopsis thaliana
835054 Arabidopsis thaliana
844332 Arabidopsis thaliana
3636229 Candida albicans SC5314
7095334 Grapevine leafroll-associated virus 10
7110730 Cyanothece sp. PCC 7424
10155152 Isosphaera pallida ATCC 43644
10187290 Cryptococcus gattii WM276
10259602 Bacteroides salanitronis DSM 18170
10889164 Simkania negevensis Z
100305036 Ictalurus punctatus
15511 Mus musculus
266759 Rattus norvegicus
100135841 Oncorhynchus mykiss
282254 Bos taurus
542423 Zea mays
100913152 Ovis aries
172757 Caenorhabditis elegans
100301691 Oncorhynchus mykiss
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