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Heat Shock Protein 90kDa beta (Grp94), Member 1 Proteins (HSP90B1)

HSP90B1 encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. Additionally we are shipping Heat Shock Protein 90kDa beta (Grp94), Member 1 Antibodies (327) and Heat Shock Protein 90kDa beta (Grp94), Member 1 Kits (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HSP90B1 22027 P08113
HSP90B1 362862 Q66HD0
HSP90B1 7184 P14625
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Top Heat Shock Protein 90kDa beta (Grp94), Member 1 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$583.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 50 μg Log in to see 9 to 11 Days
$528.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$3,107.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,297.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$777.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   2 μg Log in to see 6 to 11 Days
$142.86
Details

HSP90B1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Rat (Rattus)

Human , ,
, ,

Top referenced Heat Shock Protein 90kDa beta (Grp94), Member 1 Proteins

  1. Human HSP90B1 Protein expressed in Escherichia coli (E. coli) - ABIN668042 : Li, Dai, Zheng, Liu, Caudill: An integrated view of the roles and mechanisms of heat shock protein gp96-peptide complex in eliciting immune response. in Frontiers in bioscience : a journal and virtual library 2002 (PubMed)
    Show all 2 references for ABIN668042

  2. Human HSP90B1 Protein expressed in Wheat germ - ABIN1307186 : Crane, Han, Ahn, Oehlke, Kivett, Fedoroff, Butowski, Chang, Clarke, Berger, McDermott, Prados, Parsa: Individual patient-specific immunity against high-grade glioma after vaccination with autologous tumor derived peptides bound to the 96 KD chaperone protein. in Clinical cancer research : an official journal of the American Association for Cancer Research 2013 (PubMed)

More Proteins for Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) Interaction Partners

Rabbit Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

  1. GRP94 is tightly associated with the cell surface of parietal cells from rabbit gastric mucosa, where it exhibits high-affinity binding for the adenosine receptor agonist NECA and specific inhibitor radicicol.

Mouse (Murine) Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

  1. binding of PCSK9 (show PCSK9 Proteins) to GRP94 protects LDLR (show LDLR Proteins) from degradation likely by preventing early binding of PCSK9 (show PCSK9 Proteins) to LDLR (show LDLR Proteins)

  2. These data indicate that macrophage gp96 is essential for protective immunity during Gram-negative pneumonia

  3. gp96 participates in the generation of natural Treg cells, which might be involved in the control of liver regeneration in the periphery

  4. These studies imply GRP78 (show HSPA5 Proteins), but not GRP94, is required for mammary gland development.

  5. GRP94 deficiency in the liver led to injury, LPC (show PCSK7 Proteins) expansion, increased proliferation, activation of oncogenic signaling, progressive repopulation of GRP94-positive hepatocytes and HCC (show FAM126A Proteins) development in aged mice.

  6. GP96 serves as an essential chaperone for the cell-surface protein (show CD28 Proteins) glycoprotein A repetitions predominant (GARP (show LRRC32 Proteins)), which is a docking receptor for latent membrane-associated TGF-beta (show TGFB1 Proteins) (mLTGF-beta).

  7. this work uncovered the essential role of gp96 in regulating melanogenesis.

  8. Deletion of CD24 (show CD24 Proteins) impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells.

  9. This study uncovers novel and unique roles of GRP94 in regulating hematopoietic stem cell proliferation.

  10. gp96 is an endoplasmic reticulum heat shock protein that serves as a morphogenetic and immunoregulatory factor in syngeneic pregnancy

Human Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

  1. GRP94 knockdown cells are defective in intracellular transport and, consequently, negatively impact the trafficking of F-actin toward the cellular cortex, integrin alpha2 and integrin alphaL toward the cell membrane and filopodia

  2. Our results indicate that GRP94 and TRAP1 (show TRAP1 Proteins) might contribute more to the carcinogenesis or biology of SCLC than HSP90alpha (show HSP90AA2 Proteins) and HSP90beta (show HSP90AB1 Proteins)

  3. These results demonstrated the pivotal role of HSP90B1 in the proliferation and survival of ovarian cells, suggesting a critical role for HSP90B1 in the pathogenesis of PCOS.

  4. data suggest a role of infection-induced Gp96 shedding in the protection of the chlamydial replicative niche

  5. The authors showed that hepatitis C virus E2 protein (show UBE2B Proteins) triggers the production of TGF-beta1 (show TGFB1 Proteins) by hepatitis C virus-infected cells through overproduction of glucose-regulated protein 94 (GRP94).

  6. Hsp90-beta (show HSP90AB1 Proteins) protein was over-expressed in lung adenocarcinoma tissues and was associated with poor outcomes in early stage tumors and low pathological grade tumors.

  7. Data identified critical players in the pathogenesis of chronic lymphocytic leukemia (CLL) and shows that HSP90B1 expression is modulated by miR (show MLXIP Proteins)-223 in CLL tumor and cell lines and suggest that HSP90B1 overexpression as a new pathogenic mechanism of CLL.

  8. our findings establish GRP94 as progression markers and druggable targets in glioblastoma, relating their oncogenic effects to activation of the Wnt/b-catenin signaling pathway

  9. Grp94 was detected in plasma of type 1 diabetic but not control subjects and found linked with its N-terminus to the IgG heavy chain.

  10. HSP gp96-positive expression is closely correlated with poor survival in gallbladder cancer.

Pig (Porcine) Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

  1. structural maturation of the client protein substrate, rather than ATP binding or hydrolysis, serves as the primary signal for dissociation of GRP94-client protein complexes [GRP94]

  2. These results identify a compact, intertwined quaternary conformation of native GRP94

Cow (Bovine) Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

  1. This study showed that ubiquitinated ALK5 (show TGFBR1 Proteins) and phosphorylated heat shock protein 27 specifically accumulate in the cytoskeleton fraction, and ALK1 (show ACVRL1 Proteins) and ALK5 (show TGFBR1 Proteins) interact with heat shock protein 90(HSP90 (show HSP90 Proteins)).

Xenopus laevis Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

  1. In Xenopus, gp96 can prime CD8(+) T-cell effectors that are not MHC restricted.

Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) Protein Profile

Protein Summary

This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.

Gene names and symbols associated with HSP90B1

  • heat shock protein 90kDa beta (Grp94), member 1 (hsp90b1)
  • heat shock protein Hsp90 family protein (grp94)
  • 94 kD glucose-regulated protein (grp94)
  • heat shock protein 90kDa beta (Grp94), member 1 (HSP90B1)
  • glucose-regulated protein (GRP94)
  • glucose-regulated protein GRP94 (LOC100009456)
  • heat shock protein 90, beta (Grp94), member 1 (Hsp90b1)
  • heat shock protein 90, beta (grp94), member 1 (hsp90b1)
  • heat shock protein 90, beta, member 1 (Hsp90b1)
  • DDBDRAFT_0206450 protein
  • DDBDRAFT_0215015 protein
  • DDB_0206450 protein
  • DDB_0215015 protein
  • ECGP protein
  • endoplasmin protein
  • ERp99 protein
  • fb61d09 protein
  • Gp96 protein
  • Grp94 protein
  • HSP90B1 protein
  • hsp108 protein
  • ppk98 protein
  • TA-3 protein
  • Targ2 protein
  • tra-1 protein
  • Tra1 protein
  • wu:fb61d09 protein
  • wu:fq25g01 protein

Protein level used designations for HSP90B1

tumor rejection antigen (gp96) 1 , 94 kD glucose-regulated protein , endoplasmin , endoplasmin-like protein , Endoplasmin , 94 kDa glucose-regulated protein , endoplasmic reticulum resident protein 99 , heat shock protein 90 kDa beta member 1 , polymorphic tumor rejection antigen 1 , transforming growth factor alpha regulated gene 2 , tumor rejection antigen gp96 , heat shock protein 90kDa beta (grp94), member 1 , GRP-94 , heat shock protein 90kDa beta (Grp94), member 1 , endothelial cell (HBMEC) glycoprotein , stress-inducible tumor rejection antigen gp96 , tumor rejection antigen 1 , 98 kDa protein kinase , PPK 98 , gp96 homolog , GRP94 , heat shock protein 90kDa beta, member 1 , heat shock protein gp96 , HSP 108 , heat shock 108 kDa protein , heat shock protein 108 , transferrin-binding protein

GENE ID SPECIES
734089 Xenopus (Silurana) tropicalis
8622445 Dictyostelium discoideum AX4
100499493 Oncorhynchus mykiss
699568 Macaca mulatta
100033933 Equus caballus
100009456 Oryctolagus cuniculus
22027 Mus musculus
386590 Danio rerio
362862 Rattus norvegicus
7184 Homo sapiens
404019 Canis lupus familiaris
397191 Sus scrofa
282646 Bos taurus
399408 Xenopus laevis
374163 Gallus gallus
452187 Pan troglodytes
100174651 Pongo abelii
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