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anti-Hect Domain and RLD 5 (HERC5) Antibodies

HERC5 is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Additionally we are shipping Hect Domain and RLD 5 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HERC5 51191 Q9UII4
HERC5 514373  
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Top anti-Hect Domain and RLD 5 Antibodies at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HERC5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HERC5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB HERC5 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB HERC5 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IHC (p)   50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$639.83
Details

HERC5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,

Cow (Bovine)


Top referenced anti-Hect Domain and RLD 5 Antibodies

  1. Human Polyclonal HERC5 Primary Antibody for ELISA, WB - ABIN565561 : Woods, Kelly, Hattlmann, Tong, Xu, Coleman, Quest, Smiley, Barr: Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag. in Retrovirology 2011 (PubMed)
    Show all 2 references for ABIN565561

  2. Cow (Bovine) Polyclonal HERC5 Primary Antibody for WB - ABIN2774739 : Salon, Merdzhanova, Brambilla, Brambilla, Gazzeri, Eymin: E2F-1, Skp2 and cyclin E oncoproteins are upregulated and directly correlated in high-grade neuroendocrine lung tumors. in Oncogene 2007 (PubMed)

More Antibodies against Hect Domain and RLD 5 Interaction Partners

Human Hect Domain and RLD 5 (HERC5) interaction partners

  1. HERC5 plays a crucial role in HCC (show FAM126A Antibodies) immune evasion and has clinical relevance as a reproducible prognostic marker for risk of tumor recurrence and survival in patients.

  2. The inhibitory effect of ISG15 (show ISG15 Antibodies) on HCV RNA replication does not require its conjugation to substrates by HERC5.

  3. vIRF1 association with HERC5 altered ISG15 (show ISG15 Antibodies) modification of cellular proteins, and knockdown of ISG15 (show ISG15 Antibodies) augmented reactivation of KSHV from latency.

  4. The study reports on the NMR solution structure of a G-quadruplex formed by the CEB1 DNA G-rich fragment d(AGGGGGGAGGGAGGGTGG), harboring several G-tracts including one with six continuous guanines.

  5. Results show that HERC5 gene may be involved in regulating the spread of non-small cell lung cancer tumors where the methylation of its promoter is correlated with number increase of disseminated tumor cells and metastases as well as survival decreased.

  6. Authors identified a second distinct mechanism by which HERC5 inhibits HIV-1 replication and demonstrate that HERC5 is evolving under strong positive selection.

  7. Data indicate that income was inversely related to smoking behavior, and paternally derived CEB1 mutations were dose dependently increased when the father smoked in the 6 mo before pregnancy, 0.21 vs. 0.05 in smoking and nonsmoking fathers, respectively.

  8. The E3 ligase activity of HERC5 was required for blocking HIV-1 Gag particle production and correlated with the post-translational modification of Gag with ISG15 (show ISG15 Antibodies).

  9. This study characterizes HERC5 as a positive regulator of innate antiviral responses, and show that it sustains IRF3 (show IRF3 Antibodies) activation via a novel posttranslational modification, ISG15 (show ISG15 Antibodies)-ylation.

  10. Data show that HERC5, a functionally active HECT ubiquitin ligase, exhibits a tightly controlled cytosolic level under inflammatory conditions in endothelial cells.

Hect Domain and RLD 5 (HERC5) Antigen Profile

Protein Summary

This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

Gene names and symbols associated with HERC5

  • hect domain and RLD 5 (HERC5) antibody
  • HECT and RLD domain containing E3 ubiquitin protein ligase 5 (HERC5) antibody
  • CEB1 antibody
  • CEBP1 antibody
  • HERC5 antibody

Protein level used designations for HERC5

E3 ISG15--protein ligase HERC5 , hect domain and RLD 5 , probable E3 ubiquitin-protein ligase HERC5-like , HECT domain and RCC1-like domain-containing protein 5 , cyclin-E-binding protein 1 , probable E3 ubiquitin-protein ligase HERC5

GENE ID SPECIES
514373 Bos taurus
461369 Pan troglodytes
478474 Canis lupus familiaris
100063774 Equus caballus
100410536 Callithrix jacchus
100438710 Pongo abelii
100480303 Ailuropoda melanoleuca
100584608 Nomascus leucogenys
51191 Homo sapiens
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